326 research outputs found
Health Hazard Evaluation Determination Report HE 79-114-717: Earl Scheib Auto Painting Inc.: Denver, Colorado
No full textEnvironmental surveys were conducted and blood samples collected on August 8, 1979, to evaluate hazards from lead (7439921), chromium (7440473), nuisance dust, and paint solvents at the Earl Scheib Auto Paint Shop (SIC-7535) in Denver, Colorado. The evaluation was requested by the shop manager on behalf of the approximately 10 affected employees. Paint solvent sample concentrations were all below maximum allowable concentrations. Airborne lead concentrations ranged from undetectable to 80 micrograms per cubic meter (/m3), exceeding the OSHA standard of 50 micrograms/m3. Chromium concentrations ranged from 10 to 200 micrograms/m3, which were below the OSHA standard of 500 micrograms/m3. The particulate dust concentrations ranged from 0.4 to 2.7 milligrams (mg)/m3, which were below the OSHA standard of 15mg/m3. All blood test results were within normal ranges indicating no evidence of excessive lead exposure. The author concludes that atmospheric concentrations of chromium were above the evaluation criteria. Due to the infrequency of the exposure and the use of respirators, workers did not suffer from overexposure to lead. He recommends that the painter position himself so that air blows the spray away from him, that employees be discouraged from eating and smoking in the work area, and that clean up operations use devices that will not create additional airborne dust. [Description provided by NIOSH
The Genetic Origin of Daunians and the Pan-Mediterranean Southern Italian Iron Age Context
No full textThe geographical location and shape of Apulia, a narrow land stretching out in the sea at the South of Italy, made this region a Mediterranean crossroads connecting Western Europe and the Balkans. Such movements culminated at the beginning of the Iron Age with the Iapygian civilization which consisted of three cultures: Peucetians, Messapians, and Daunians. Among them, the Daunians left a peculiar cultural heritage, with one-of-a-kind stelae and pottery, but, despite the extensive archaeological literature, their origin has been lost to time. In order to shed light on this and to provide a genetic picture of Iron Age Southern Italy, we collected and sequenced human remains from three archaeological sites geographically located in Northern Apulia (the area historically inhabited by Daunians) and radiocarbon dated between 1157 and 275 calBCE. We find that Iron Age Apulian samples are still distant from the genetic variability of modern-day Apulians, they show a degree of genetic heterogeneity comparable with the cosmopolitan Republican and Imperial Roman civilization, even though a few kilometers and centuries separate them, and they are well inserted into the Iron Age Pan-Mediterranean genetic landscape. Our study provides for the first time a window on the genetic make-up of pre-Roman Apulia, whose increasing connectivity within the Mediterranean landscape, would have contributed to laying the foundation for modern genetic variability. In this light, the genetic profile of Daunians may be compatible with an at least partial autochthonous origin, with plausible contributions from the Balkan peninsula
Equal Employment Opportunity Commission vs. Earl Scheib, Inc., d/b/a Earl Scheib Paint & Body
No full textEEOC_v__Earl_Scheib__Inc_SCANNED.pdf: 29 downloads, before Oct. 1, 2020
Equal Employment Opportunity Commission vs. Earl Scheib, Inc., d/b/a Earl Scheib Paint & Body
No full textA fresh perspective on infrared spectroscopy as a prescreening method for molecular and stable isotopes analyses on ancient human bones
No full textFollowing the development of modern genome sequencing technologies, the investigation of museum osteological finds is increasingly informative and popular. Viable protocols to help preserve these collections from exceedingly invasive analyses, would allow greater access to the specimens for scientific research. The main aim of this work is to survey skeletal tissues, specifically petrous bones and roots of teeth, using infrared spectroscopy as a prescreening method to assess the bone quality for molecular analyses. This approach could overcome the major problem of identifying useful genetic material in archaeological bone collections without resorting to demanding, time consuming and expensive laboratory studies. A minimally invasive sampling of archaeological bones was developed and bone structural and compositional changes were examined, linking isotopic and genetic data to infrared spectra. The predictive model based on Infrared parameters is effective in determining the occurrence of ancient DNA (aDNA); however, the quality/quantity of aDNA cannot be determined because of the influence of environmental and local factors experienced by the examined bones during the burial period
Armando Ghitalla : orchestral trumpeter, soloist, and pedagogue (1925-2001)
No full textThis study documents the performing and teaching career of Armando Ghitalla (1925-2001), and describes his pedagogical approach with an emphasis on understanding his approach to teaching embouchure. It includes as appendices a comprehensive discography of his solo, chamber, and orchestral recordings, a listing of his solo performances with the Boston Symphony Orchestra, a selected list of former students, and copies of his advanced flexibility and transposition studies.The personal interview served as the primary source of data for this study. The subject, Armando Ghitalla, participated in an in-depth interview with the author which was recorded and transcribed. Subsequent data was gathered from former students through the use of an open-ended questionnaire. Follow-up interviews were held with several of the respondents. Previously published articles, interviews, reviews, and an unpublished recording of a trumpet clinic were also consulted.Ghitalla was a member of the Boston Symphony Orchestra for twenty-eight years, serving as solo trumpet of the Boston Pops Orchestra from 1951-1965 and principal trumpet of the Boston Symphony Orchestra from 1965-1979. He was active as a virtuoso trumpet soloist and had a distinguished career as a trumpet professor following his retirement from the Boston Symphony. His success as an orchestral performer, solo performer, and noted pedagogue distinguish him from many of his contemporaries.Thesis (D.A.)School of Musi
Juvenile homicide : a criminological study on the possible causes of juvenile homicidal delinquency in Jamaica
No full textJamaica, the so-called land of wood and water, normally is the embodiment of a dream holiday destination with white sandy beaches, tropical palm trees, dazzling sunshine and the typical Caribbean flair. Generally, murder and manslaughter are not associated with Jamaica. However, international comparisons of crime rates reveal that Jamaica has persistently had one of the highest homicide rates in the world. Jamaica has been described as the murder capital of the world in 2006 by the BBC news after more than 1’600 people were killed in the year 2005; a tally of at least five people murdered a day. The majority of the homicides are caused by young men. Despite the dimension and severity of the homicidal problem in Jamaica, it is astonishing that literature on this phenomenon in Jamaica is very sparse and the literature that is available either doesn’t conform to the current homicide situation in Jamaica anymore or is inconsistent with other studies. The aim of the present research study was thus to close this gap and to help the process of comprehending the problem of fatal juvenile delinquency by engaging empirical research in serious efforts to describe and explain the epidemic. According to the author, understanding juvenile homicidal delinquents and their actions and thus ascertaining a plausible explanation for their high homicide rate can only be achieved by going back to those whose acts are to be explained: The juvenile homicidal delinquents themselves. The findings of the present study are therefore based upon the data gathered by means of 20 face-to-face, semi-standardised interviews with young men who have committed at least one homicide during the last five years prior to the interview and were aged between 12 and 25 years at the time of the respective homicide(s). The author acts on the assumption that homicides by juveniles can be understood as a reaction that emerges situationally and is based on a complex bundle of causes which leads to an increased susceptibility to homicides. The aim of the present study was to generate a plausible and scientifically substantiated hypothesis to explain the high proportion of male juveniles responsible for the homicide rate in Jamaica. Three groupings were examined: The individual personality characteristics of the homicide delinquents, the social context influencing the individual’s thoughts and actions and the triggering factors in the homicide context.
The study comes to the conclusion that the homicides of the respondents of the present study – additionally to the basic prerequisites of the occurrence of homicides in general such as a life in deprivation and the failure of the institutions of socialisation to sufficiently socialise their members – can be explained in high gear by the widely dispread culture of violence. Within this culture, violence constitutes a part of every-day behaviour and killing is perceived as a legitimate form of dispute resolution to which one has adapted because it utterly works. This is an instrumental understanding of violent behaviour. This apparent culture of violence of the underclass society with the deeply embedded willingness to apply violence to solve even seemingly minor disputes is intensified by a high gun prevalence and easy firearm accessibility as well as the wide distribution of and attachment to gangs. Firearms as well as delinquent gangs are two powerful factors that accord power, a feeling of strength and superiority to the individual. Status, power and respect rank high within the impecunious underclass society in Jamaica. Violence is perceived as a necessary instrument to sustain the own identity, status and respect. Thus, the fight for respect in the street culture of Jamaica’s urban inner-city youth depicts an act in self-defence for the parties involved. And such an act in self-defence legitimises to kill
The geochemistry of niobium and its distribution and relative mobility in agricultural soils of Europe
No full textIt is reported and discussed the distribution of niobium in agricultural soils of Europe, as a result of a research conducted within the GEMAS project
Characterizing the Evolution of a Cadherin Bond Involved in Sensory Perception
No full textMy work on this project was catalyzed by a previous graduate student, Dr. Collin Nisler, who selected the non-mammalian species I worked with and ordered the template DNA of my construct. The protein structure that I determined was published in a paper with Dr. Nisler, where he is first author, and I am co-second author.
https://doi.org/10.1093/molbev/msad057Vertebrate hair cells have evolved over 500 million years to function as the exquisitely precise and robust mechanosensors that we see in humans today. These hair cells transform mechanical stimuli into electrochemical signals for brain processing, ultimately allowing hearing to occur. Facilitating this process are bundles of small hair-like structures referred to as stereocilia that are present at the apical surface of hair cells in the inner ear. Connecting each stereocilium to its neighbor on this bundle is the tip link, a protein filament which gates ion channels. When sound vibrations stimulate the inner ear, these bundles are deflected, and tip links are stretched. This stretching triggers the flow of potassium ions through ion channels, which ultimately allows for sound waves to be converted into electrical impulses for the brain to interpret.
In vertebrates, two proteins, cadherin-23 (CDH23) and protocadherin-15 (PCDH15) interact with one another to form tip links. Each of these proteins has numerous extracellular cadherin (EC) repeats crucial for adhesion. X-ray crystal structures of mouse protein fragments have demonstrated that this interaction is mediated by the protein tips (EC1-2), which engage in an antiparallel "handshake complex". Additional in vivo and in vitro experiments along with genetic analyses illustrate that this handshake complex is essential for hearing to occur for both mice and humans. However, our understanding of this vital filament in non-mammalian species remains limited.
Here, a range of biochemical techniques were utilized to begin to characterize the evolutionary path of this protein complex. Our results suggest a fundamental binding mechanism between CDH23 and PCDH15 throughout all vertebrates and paralogs, despite evolutionary sequence variations. Our work asserts that while the CDH23 and PCDH15 interaction seems to be universally conserved, distinct biophysical properties, such as complex strength and rate of binding, may vary among different vertebrate lineages. Furthermore, high-speed atomic force microscopy imaging was utilized to characterize full-length PCDH15 ectodomain paralogs in fish, revealing intriguing structural attributes.Beckman Foundation, Beckman Scholars ProgramA one-year embargo was granted for this item.Academic Major: Biochemistr
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