57 research outputs found
Data on eNOS T786 and G894T polymorphisms and peripheral blood eNOS mRNA levels in Sickle Cell Disease
No full textIn this article, we present data on endothelial Nitric Oxide Synthase (eNOS) gene T786C and G894T polymorphisms in Greek steady-state Sickle Cell Disease patients in comparison to healthy controls. Moreover, eNOS mRNA levels were determined in peripheral blood samples from 18 patients and 9 controls. This article complements our recently published article named “Prognostic value of eNOS T786C and G894T polymorphisms in Sickle Cell Disease” (I. Armenis, V. Kalotychou, R. Tzanetea, Z. Kontogeorgiou, D. Anastasopoulou, M. Mantzourani, M. Samarkos, K. Pantos, K. Konstantopoulos, I. Rombos, 2016) [1]. © 2016 The Author
Vista frontal cajonera.
No full textSacristía.-Anónimo español.- Cajonera con decoración tallada de cruces, de rombos y de rectángulos con forma de "L" y de "T"; mientras que en el centro se aprecia una decoración de rocalla enmarcada en un cuadrado
The role of IL-15 in central nervous system disorders
No full textIL-15 is a proinflammatory cytokine. It is produced by activated blood monocytes, macrophages, dendritic cells, and activated glial cells. It promotes T-cell proliferation, induction of cytolytic effector cells including natural killer and cytotoxic cells and stimulates B-cell to proliferate and secrete immunoglobulins. Little information is available on the exact role of IL-15 in the neurological diseases. Microglial cells are the main regulators of both innate and adaptive immune responses in the central nervous system (CNS). IL-15 may be involved in the inflammatory reactions and microglial activation of some common CNS disorders such as multiple sclerosis, Alzheimer’s and Parkinson’s disease, but its exact role in their pathogenesis is not clear
Tarentola protogigas PROTOGIGAS JOGER 1984
No full text<i>TARENTOLA PROTOGIGAS</i> JOGER 1984 B <p> <i>Diagnosis:</i> Medium to large-sized gecko [maximum SVL 98.5 mm (Schleich, 1987); 71.9 mm on average, see Appendix 2]; eye/ear opening ratio averages 1.69; ear–eye/eye–snout distance ratio averages 0.75. Eight to 12 supralabials; seven to nine infralabials; ten to 13 enlarged lamellae under the 4th finger; 144–181 midbody scales (Joger, 1984b); conical to apical prominent dorsal tubercles with a narrow central keel (Fig. 5D 4), especially on the sacral region, with 12–15 transverse rows and 15–21 longitudinal rows; several enlarged tubercles between the eye and the ear opening. Grey, brownish to yellowish dorsal pattern with a series of four (sometimes five) light middorsal patches, each preceded by a more indistinct and lighter W-shaped dark mark, usually connected by a light middorsal line (Figs 6D 3–5 and 7D 3–5); goldenyellowish grey ventral parts; dark spots on the labials, sometimes creating an alternating light and dark pattern; eye iris grey with an indistinct broad horizontal dark area.</p> <p> It differs from <i>T. bocagei</i>, <i>T. fogoensis</i>, <i>T. darwini</i>, <i>T. substituta</i>, <i>T. raziana</i>, <i>T. caboverdiana</i>, and <i>T. nicolauensis</i> by having prominent conical dorsal tubercles, enlarged tubercles between the eye and ear opening and a different dorsal pattern (Fig. 6), and from <i>T. gigas</i> by the presence of a narrow wellmarked central keel, especially on the sacral region. It also differs from <i>T. gigas</i> by having important morphological, bioacustical, ecological, and behavioural differences. It differs from <i>T. boavistensis</i>, <i>T. rudis</i>, and <i>Tarentola</i> from Maio by its yellower ventral coloration. It also differs from <i>T. rudis</i> by a higher number of scales around midbody and interorbital scales [18–21 versus 16–19 (Joger, 1984b)], by having four to five more indistinct and lighter W-shaped dorsal bands (Fig. 6), fader spots on the labials and less contrasted eye iris coloration (Fig. 7). It differs from <i>Tarentola</i> from Maio by a higher number of scales and lamellae under the fifth toe [22–26 versus 19–21, rarely 22 (Joger, 1984b)] and interorbital scales [19–21 versus 16–18 (Joger, 1984b)].</p> <p> <i>Distribution:</i> The southern islands of Fogo, Brava, and Rombos Islets, Cape Verde.</p> <p> <i>Genetic and phylogeographical remarks: Tarentola protogigas</i> is monophyletic (Fig. 2) and presents a considerable level of genetic divergence from other sister taxa from clade D, as <i>T. gigas</i>, <i>T. rudis</i>, and <i>Tarentola</i> from Maio: D3–D1, D3–D2, and D3–D6 <i>p-</i> dist (cyt <i>b</i>) = 2.5 ± 1.2, 2.6 ± 0.9, and 5.3 ± 1.2%, respectively (Table 5). The population from Fogo presents a considerable level of genetic divergence with the populations from Brava and Rombos: D3–D4 and D3–D5 <i>p-</i> dist (cyt <i>b</i>) = 2.1 ± 0.8 and 2.3 ± 0.8%, respectively. However, the <i>Snn</i> test values for PDC, ACM4, and MC1R are not significant between <i>T. protogigas</i> from Fogo versus Brava and Rombos (Appendix 5). The population from Brava presents very low values of genetic divergence with the population from Rombos: D4–D5 <i>p-</i> dist (cyt <i>b</i>) = 0.4 ± 0.3%. Therefore, only one of the three lines of evidence (morphology) differentiates the population of Fogo from Brava and Rombos. Consequently, according to the IPC protocol, <i>T. p. protogigas</i> and <i>T. p. hartogi</i> comb. nov. are considered only distinct subspecies (Fig. 2). The lack of differentiation in at least two of the three lines of evidence precludes any further differentiation between the island populations from Brava and Rombos.</p> <p> <i>TARENTOLA PROTOGIGAS PROTOGIGAS</i> JOGER,</p>Published as part of <i>Vasconcelos, Raquel, Perera, Ana, Geniez, Philippe, Harris, D. James & Carranza, Salvador, 2012, An integrative taxonomic revision of the Tarentola geckos (Squamata, Phyllodactylidae) of the Cape Verde Islands, pp. 328-360 in Zoological Journal of the Linnean Society 164 (2)</i> on page 353, DOI: 10.1111/j.1096-3642.2011.00768.x, <a href="http://zenodo.org/record/5406490">http://zenodo.org/record/5406490</a>
Aconibe
No full textDestinatario: Población localPoblado experimental de agrupación de población rural compuesto de 50 viviendas adosadas, con plantas en forma de T y de Z. Las viviendas conforman varias manzanas organizadas en rombos con pasos peatonales a su interior. En el centro se halla una iglesia, una junta vecinal (o casa de la palabra) y una fuente. En el frontal, junto a la carretera, se hallan varias tiendas. Las viviendas son de diferentes tipos, con dos, tres y cuatro dormitorios. Su desarrollo es en planta baja, con techos a dos aguas, y porche de entradaEstado actual: Aparentemente no construid
Alterations of T-cell subpopulations in patients with ALS. Evidence of systemic immune response?
No full textERYTHROCYTOSIS DUE TO A COMBINATION OF THE HIGH OXYGEN AFFINITY HEMOGLOBIN VARIANT, Hb OLYMPIA [beta 20(B2)VAL -> MET] WITH beta- AND alpha-THALASSEMIA MUTATIONS: FIRST CASE IN THE LITERATURE
No full textA 40-year-old Greek male was admitted to the hospital because of acute respiratory infection. The patient has been undergoing regular venesection for erythrocytosis for 20 years; he has also been taking oral anticoagulants for thrombosis for 15 years. The molecular defect for erythrocytosis was detected together with the rare Hb Olympia (HBB:c.61G>A) variant. This hemoglobin (Hb) variant was found in combination with two thalassemia-type globin gene defects, namely beta(0)-thalassemia (beta(0)-thal), HBB:c.118C>T and alpha(0)-thal (–(MED)). This combination of three molecular defects is the first such case reported in the literature
Elektrophoretische Untersuchungen der verschiedenen Gerinnungsfaktoren des Blutes
No full textZusammenfassungWir haben elektrophoretische Untersuchungen der Gerinnungsfaktoren mit der Methode der Papierelektrophorese durchgeführt. Dabei konnten wir feststellen, daß die Wanderungsorte dieser Faktoren auf dem elektrophoretischen Streifen folgende sind:1. Das Prothrombin wandert zum α-Globulin und bleibt zwischen diesem und dem Albumin liegen.2. der Faktor V (Proaccelerin), der Faktor VII (Prokonvertin), der Anti-Hämophilie-Faktor A und der Antihämophilie-Faktor B sind zwischen β- und γ-Globulin näher am ß-Globulin zu finden.3. Der fehlende Faktor bei zwei hämophilieähnlichen Fällen, welche weder zur Form A noch zur Form A gehören, und bei denen wahrscheinlich der P. T. F.-D- oder ein anderer auch temperaturempfindlicher Faktor fehlt (da eine Hämophilie C ebenfalls mit Wahrscheinlichkeit auszuschließen ist), besteht aus zwei Fraktionen, wie die elektrophoretischen Untersuchungen ergaben. Die eine nimmt bei der Elektrophorese eine Stelle zwischen β- und γ-Globulin und die andere zwischen β- und α-Globulin ein.</jats:p
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