1,246 research outputs found
From hypertext to hype and back again: exploring the roots of social media in the early web
No full textPreprint of chapter from the SAGE Handbook of Social Media (Burgess, Marwick and Poell, eds., 2018). "How should we think of the relationship between social media and the early web, and what can we learn from this history?
Pratulum quinarium Marwick 1944
No full textPratulum quinarium (Marwick, 1944) (Fig. 6) Nemocardium (Pratulum) quinarium Marwick, 1944: 266; pl. 36, figs. 10, 16. Material. Sixteen specimens, 12 numbered: two from Moonlight North (Y16/f0694), L4653 (Fig. 6 A), L4654 (Fig. 6 D); 14 from Tauwhareparae (Y16/f0539), L4655 (Fig. 6 C), L4656–4663, L4664 (Fig. 6 B), UOA. Remarks. Details of the muscle scars of Pratulum quinarium (Marwick, 1944) remained unobserved or unreported before this study, and are described here from a single small specimen (Fig. 6 A). The anterior adductor scar is elongate dorsoventrally, rather thin anteroposteriorly; posterior adductor scar arcuate, about twice as wide (anteroposteriorly) as anterior adductor scar, ca. 50% longer dorsoventrally, situated slightly lower than anterior adductor scar; pallial line entire, parallel to (antero- and postero-) ventral margin and rather distant from it (ca. 60– 70% towards margin from shell centre). The occurrence of P. quinarium at two Lillburnian-age New Zealand fossil seep sites extends the stratigraphic range of this species back from its previous earliest report in the Tongaporutuan. In fact, none of the species currently assigned to Pratulum have ever been recorded from the Lillburnian, but the genus is known throughout the Cenozoic from Danian to Recent (Beu & Maxwell 1990). P. quinarium is morphologically close to Pratulum pulchellum (Gray, 1843), distinguished from it by the finer and more numerous ribs, and by the narrow interstices, well developed transverse bars and absence of tubercles on the posterior area (Marwick 1944). At 11–13 mm in length, P. quinarium is among the smallest of New Zealand cardiids. The specimens were predominantly found in a single aggregation at Tauwhareparae, reflecting a gregarious habit that is typical for the genus.Published as part of Saether, Kristian P., Jingeng, Sha, Little, Crispin T. S. & Campbell, Kathleen A., 2016, New records and a new species of bivalve (Mollusca: Bivalvia) from Miocene hydrocarbon seep deposits, North Island, New Zealand, pp. 1-26 in Zootaxa 4154 (1) on pages 11-12, DOI: 10.11646/zootaxa.4154.1.1, http://zenodo.org/record/27215
Rationale and design of a trial to personalize risk assessment in familial coronary artery disease
No full textAbstract not availableThomas H Marwick, Kristyn Whitmore, Stephen J Nicholls, Tony Stanton, Geoffrey Mitchell, Andrew Tonkin, Christopher Blizzard, Amanda Neil, Catherine Jones and Gerald F Watts, on behalf of the CAUGHT-CAD investigator
Assessment of subendocardial structure and function
No full textThe combination of high energy expenditure and the borderline adequacy of perfusion make the subendocardium uniquely vulnerable to injury. Selective subendocardial involvement is usually a marker of subclinical disease. Technical advances in new noninvasive imaging modalities, especially in spatial resolution, now permit qualitative and quantitative assessment of subendocardial structure, function, and perfusion. Many newer techniques have the potential to provide superior prognostic information to current standard assessment methods. This review describes the contemporary capabilities of multiple imaging modalities for assessment of the subendocardium, and seeks to guide the clinician regarding the information and technical deficiencies of each modality. © 2010 American College of Cardiology Foundation.No Full Tex
Impact of a coronary artery calcium-guided statin treatment protocol on cardiovascular risk at 12 months: Results from a pragmatic, randomised controlled trial
No full textBackground and aims Coronary artery calcium (CAC) may encourage patients to adhere to primary prevention recommendations. This study sought to evaluate the benefit of a CAC-guided risk-management protocol in those with a family history of premature coronary artery disease (FHCAD). Methods In this Australian multi-centre, randomized controlled trial (Coronary Artery Calcium score: Use to Guide management of Hereditary Coronary Artery Disease, CAUGHT-CAD), asymptomatic, statin-native participants at low-intermediate cardiovascular risk with FHCAD underwent CAC assessment. Those with CAC between 1 and 400 were randomized (1:1) to disclosing the CAC result to both patient and physician and commencing atorvastatin (intervention) or blinding the CAC result with risk factor education only (control). The primary endpoint of this sub-study was change in Pooled Cohort Equation (PCE) at 12 months. Results Of 1088 participants who were scanned, 450 were randomised and 214 in both groups completed 1-year follow-up. At 1 year, PCE-risk decreased by 1.0% (95% CI 0.13 to 1.81) in the CAC-disclosed group and increased by 0.43% (95%CI 0.11-0.75) in the CAC-blinded group. LDL-C decreased in the CAC-disclosed group in both those who continued (1.5 mmol/L; 95% CI 1.36 to 1.74) and discontinued statins (0.62 mmol/L; 95% CI 0.32 to 0.92) but was unchanged in the CAC-blinded group.ConclusionParticipants unblinded to their CAC showed reductions in LDL irrespective of statin continuation when compared to controls at 12 months. Improvements in individual risk factors and PCE risk were also noted. CAC assessment may positively influence patients and physicians to improve risk factor control.Prasanna Venkataraman, Quan Huynh, Stephen J. Nicholls, Tony Stanton, Gerald F. Watts, Thomas H. Marwick, on behalf of theCAUGHT-CAD investigator
Swaziland's relations with Britain and South Africa since 1968
No full textThis work looks into Swaziland's political, economic, social and cultural relations with Britain (its former colonial master) and South Africa (its big and rich neighbour) in the period since Swaziland's Independence in 1968. The focus is on how Swaziland's relations with Britain and South Africa influence its socio-economic and political developments, and its internal and external security. As a micro-state, with a population of less than 0.7 million people, the assumption is made that Swaziland's progress and security can be reasonably assessed by examining its relations with the two powerful states with whom it has close links. This assumption arises from the fact that (i) Swaziland inherited political institutions from Britain, (ii) there were strong economic links (investments, trade, aid) between it and Britain at Independence and these ties continue today, (iii) there were, and still are, economic links in almost every aspect between Swaziland and South Africa at Independence and (iv) South Africa dominates the Southern Africa region - militarily and economically. The main arguments in the Thesis are (a) that the economic links between Swaziland and the two states provide economic growth for the former, thus helping to maintain stability, although South African domination threatens to undermine Swaziland's independence (b) that Swaziland has pursued a "tightrope policy" in Southern Africa, and that this regional strategy has, on the whole, succeeded in helping the country's survival; and (c) that the political system of Swaziland has an in-built tension in that the traditional institutions exist alongside modern ones and this is a threat to political stability
Evaluation of the Dallas freeway corridor system.
No full textDistributed by NTIS.Prepared for U.S. Traffic Systems Division ; DOT-FH-11-9611.Prepared by Bart Cima et al. ; Peat, Marwick, Mitchell & Co. et al.Spine title: Dallas freeway corridor evaluation.Cover title.Final report.Includes bibliographical references.Mode of access: Internet
Hemodynamic benefit of rest and exercise optimization of cardiac resynchronization therapy
No full textThe optimal method of cardiac resynchronization therapy (CRT) optimization is as yet unknown. We sought to investigate the responses of optimization at rest and on exercise. This 2 stage study involved 59 patients (age 65 ± 10, 75% male), who had all recently undergone successful CRT implantation. In the first stage, the 6-month response was compared between 30 individuals who underwent resting echocardiographic optimization of CRT [atrioventricular (AV delay) plus ventriculo-ventricular delays (VV delay)], compared with the 29 who did not. In the second stage, a subset of 37 patients from the original cohort were randomized (double-blind) to either resting echocardiographic optimization (n = 20) or exercise echocardiographic optimization (n = 17) and followed for a further 6 months. Clinical and echocardiographic data were collected at each stage. Patients undergoing rest optimization demonstrated improvement in almost all variables and significantly in B-type natriuretic peptide (BNP) in contrast to those without optimization. In a linear regression model, the only significant predictor of BNP change was whether an individual underwent resting optimization or not (β = 0.38, P = 0.04). In those undergoing resting optimization, the degree of change in AV delay was correlated with improvement in left ventricle (LV) end-diastolic volume (r2 = 0.33, P < 0.01). Optimization on exercise was associated with a significant decrease in 6-minute walk test compared to those randomized to rest optimization possibly due to inducing nonoptimization at rest. In conclusion, echocardiographic optimization of CRT at rest is superior to no optimization or optimization on exercise. Patients with the greatest change in AV delay to reach optimal may undergo greater LV remodeling.No Full Tex
Prediction of all-cause mortality from global longitudinal speckle strain: Comparison with ejection fraction and wall motion scoring
No full textBackground-Although global left ventricular systolic function is an important determinant of mortality, standard measures such as ejection fraction (EF) and wall motion score index (WMSI) have important technical limitations. The aim of this study was to compare global longitudinal speckle strain (GLS), an automated technique for measurement of long-axis function, with EF and WMSI for the prediction of mortality.Methods and Results-Of 546 consecutive individuals undergoing echocardiography for assessment of resting left ventricular function, 91 died over a period of 5.2±1.5 years. In addition to Simpson biplane EF, WMSI was determined by 2 experienced readers and GLS was calculated from 3 standard apical views using 2D speckle tracking. The incremental value of EF, WMSI, and GLS to significant clinical variables was assessed in nested Cox models. Clinical factors associated with outcome (model x22=20.2) were age (hazard ratio [HR], 1.46; P35% and those with and without wall motion abnormalities. A GLS ≥-12% was found to be equivalent to an EF ≤35% for the prediction of prognosis. Intraobserver and interobserver variations for EF and GLS were similar. Conclusions-GLS is a superior predictor of outcome to either EF or WMSI and may become the optimal method for assessment of global left ventricular systolic function. (Circ Cardiovasc Imaging. 2009;2:356-364.) Copyright © 2009 American Heart Association, Inc.No Full Tex
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