1,372 research outputs found
Goed geregelde jeugdzorg?
No full textHoofdstuk in Zorgen dat het werkt: werkzame factoren in de zorg voor jeugd.
'Waarom is er zoveel kritiek op de moderne jeugdzorg, die verkokerd, bevoogdend en niet vraaggericht zou zljn? Vaak wordt er gewezen op de gefragmenteerde organisatie, op de niet heldere verdeling van
bestuurliike verantwoordelijkheden, op de bureaucratische processen en op de perverse prikkels in het financieringssysteem.Zonder twijfel is er in al die bestuurlijke tuintjes nogal wat onkruid te wieden en kan het hele stelsel eenvoudiger en transparanter. In dit hoofdstuk wordt echter de stelling betrokken dat bestuurlijke reparaties de problemen niet zullen oplossen. Er ligt een dieper, meer zorginhoudelijk problem ten grondslag aan de genoemde problemen
Acute ingestion of dimethylformamide results in extensive formation of methylcarbamoylated hemoglobin - A case report
No full textAcute ingestion of dimethylformamide results in extensive formation of methylcarbamoylated hemoglobin - A case report
No full textJarlmanns saga og Hermanns: A Translation
No full textAgnete Lothʼs edition of the longer version of Jarlmanns saga og Hermanns included an accompanying English paraphrase (by Gillian Fellows Jensen), but there has never been a full translation into English, much less of the shorter version as edited by Hugo Rydberg. We rectify that omission here, providing a normalized text of Rydbergʼs edition with an English translation alongside in the hopes of making this entertaining saga more accessible to a wider audience
Can multicentre urodynamic studies provide high quality evidence for the clinical effectiveness of urodynamics? ICI-RS 2019
No full textAims Lower urinary tract (LUT) function can be investigated by urodynamic studies (UDS) to establish underlying functional abnormalities in the LUT. A multicentre registry could present an opportunity to improve the scientific evidence base for UDS. During the International Consultation on Incontinence Research Society (ICI-RS) meeting in Bristol, United Kingdom 2019, an expert panel discussed the potential of a multicentre urodynamic registry to improve the quality of urodynamic output. Methods the potential importance of a multicentre urodynamic registry, parameter inclusion, quality control, and pitfalls during a registry roll-out were reviewed and discussed. Results and Conclusions The clinical utility, evaluation, and effectiveness of UDS remain poorly defined due to a lack of high quality evidence and large study populations. Therefore, the ICI-RS proposes formation of a urodynamic panel for future roll-out of a registry. The inclusion of basic parameters was discussed and the essential parameters were defined as well as the potential pitfalls of a registry roll-out. The discussion and recommendations in this paper form the base for future urodynamic registry development
Assessing attitudes towards insulin pump therapy in adults with type 1 diabetes: Italian validation of the Insulin Pump Attitudes Questionnaire (IT-IPA questionnaire)
No full textAims: The aim of the study was to adapt the German version of the insulin pump therapy (IPA) questionnaire to Italian (IT-IPA) and to evaluate its psychometric properties in adults with type 1 diabetes. Methods: We conducted a cross-sectional study, data were collected through an online survey. In addition to IT-IPA, questionnaires evaluating depression, anxiety, diabetes distress, self-efficacy, and treatment satisfaction were administered. The six factors identified in the IPA German version were assessed using confirmatory factor analysis; psychometric testing included construct validity and internal consistency. Results: The online survey was compiled by 182 individuals with type 1 diabetes: 45.6% continuous subcutaneous insulin infusion (CSII) users and 54.4% multiple daily insulin injection users. The six-factor model had a very good fit in our sample. The internal consistency was acceptable (Cronbach’s α = 0.75; 95% IC [0.65–0.81]). Diabetes treatment satisfaction was positively correlated with a positive attitude towards CSII therapy (Spearman’s rho = 0.31; p < 0.01), less Technology Dependency, higher Ease of Use, and less Impaired Body Image. Furthermore, less Technology Dependency was associated with lower diabetes distress and depressive symptoms. Conclusions: The IT-IPA is a valid and reliable questionnaire evaluating attitudes towards insulin pump therapy. The questionnaire can be used for clinical practice during consultations for shared decision-making to CSII therapy
The effect of adding ethanol on the ignition properties of fast pyrolysis bio oils
No full textIn this paper, the ignition behaviour of droplets composed by crude FPBO and FPBO/EtOH blends at normal pressure is discussed. The tests were carried out, in a closed single droplet combustion chamber with optical accesses, on droplets of diameter in the range 0.8 mm-1.4 mm. FPBO/EtOH blends with percentage of alcohol varying between 5 % v/v and 50 % v/v were tested. To analyse the effectiveness of the addition of ethanol on the ignition properties of FPBOs, the study was also carried out on the crude FPBO used to form the blends. 1D modelling of the evaporation and ignition of droplets of crude FPBO and blends FPBO/EtOH is also discussed. The comparison of numerical and experimental results shows that the model is able to capture the main features of the heating phase of the complex fuels forming the droplets
N11-01: Arthroskopie des Kniegelenks bei Gonarthrose [Arthroscopy of the knee joint for gonarthrosis]
No full textImproved survival in metastatic germ-cell cancer
No full textBackground: The prognostic score of the International Germ Cell Cancer Collaborative Group (IGCCCG) in metastatic germ-cell cancers (mGCC) relies on treatments delivered before 1990. It is unclear, if this score is still relevant to contemporary cohorts of patients who receive modern-type chemotherapy and supportive care.
Patients and Methods: All patients who underwent cisplatin/etoposide based first-line chemotherapy for mGCC at the University Hospital Zurich (USZ) between 1991 and 2016 were identified retrospectively. Clinical characteristics were extracted from medical charts and patients classified according to the IGCCCG score (J Clin Oncol 1997;15:594). Progression-free survival (PFS) and overall survival (OS) probabilities at 5 years served as outcome parameters.
Results: The study cohort consisted of 204 patients at a median age of 32 years and a median follow-up of 4.2 years. According to the IGCCCG score, PFS in the contemporary USZ cohort was 71% overall; 83% for good risk, 69% for intermediate risk and 30% for poor risk patients, p < 0.001. OS for the entire cohort was 88%. In respect to OS, we observed no difference between good risk and intermediate risk patients (94% vs. 91%, p = 0.62), but a statistically significant difference between those two risk groups and poor risk patients, who had an OS of only 65%, p < 0.001.
Conclusions: Within the contemporary USZ cohort of mGCC patients no improvements in PFS probabilities were observed compared to the ones predicted by the IGCCCG score for any prognostic category, but marked improvements in OS probabilities for intermediate risk and poor risk patients, possibly due to better salvage treatments
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