52 research outputs found
Re-interpreting the Poems and Paintings of the Lotus Sutra by a Correspondence Analysis and the Visualization of a Dimension Reduction: The Philosophy of Aristocratic Life during the Japanese Medieval Age
No full textThis presentation intends to explore the correlation between Waka literature and the paintings of the whole Lotus Sutra in Japan from the eleventh to fourteenth centuries, as derived from a correspondence analysis between the two, using extracted vocabularies of annotation and visualization by applying a dimension reduction. In addition, I mainly analyze the twenty-one imperially commissioned poetry anthologies for the literature of the Lotus Sutra, and for paintings, I focus on the frontispieces of the Lotus Sutras written in gold and silver inks on indigo-dyed papers. In particular, I attempt to reinterpret the visualization of dimension reduction by using a new method such as t-SNE (t-distributed Stochastic Neighbor Embedding）in addition to conventional PCA (principal component analysis) to emphasize the differences instead of similarities. This may further reveal the literary peculiarities of the rhetoric, the nature of the “narrative”, or the visual arts-specific rhetoric such as “decoration” and newer contexts
Renal artery embolism treated by selective intra-arterial infusion of tissue plasminogen activator: report of 2 cases
No full text組織プラスミノーゲンアクチベータにて選択的腎動脈線溶療法を施行した腎動脈塞栓症2例(74歳女, 66歳女)を報告した.1例は発症後3日目の治療にもかかわらず塞栓が溶解され腎機能が回復したTwo cases of renal artery embolism treated by selective intra-arterial infusion of tissue plasminogen activator (t-PA) are reported. A 74-year-old woman with atrial fibrillation presented with left flank pain of 54-hour duration. Selective renal angiography revealed embolic obstruction of multiple segmental arteries in the left kidney. She was treated by one-shot intra-arterial t-PA infusion (8, 000, 000 units) and intravenous heparinization (25, 000 units/3 days). Although fibrinolysis was successful except for most distal arterial branches, complete recovery of renal function was not obtained. A 66-year-old man presented with complete obstruction of left main renal artery. He had hyperthyroidism and atrial fibrillation. At 75 hours after onset of left flank pain, he was treated by one-shot intra-arterial t-PA infusion (18, 000, 000 units) and intravenous heparinization (4, 000 units/24 hours). His renal function was recovered completely. Selective intraarterial t-PA infusion is considered an effective treatment for renal artery embolism
Fundamental differentiation and growth characterization of murine embryonic stem cells in varied culture conditions
No full textThesis (M. Eng.)--Massachusetts Institute of Technology, Biological Engineering Division, 2004.Includes bibliographical references (leaves 81-83).Although embryonic stem (ES) cells and their pluripotent capability have been elucidated for decades, little study has been done on obtaining the pluripotency profile of ES cells in the incipient stages of differentiation. In this research, an ES cell line with transfected green fluorescent protein (GFP) co-expressed by an Oct-4 promoter was analyzed by fluorescence-activated cell sorter (FACS) to obtain such profile. As Oct-4 is an ES cell differentiation marker whose expression varies with pluripotency, GFP expression could simply be measured in these cells to determine how pluripotent they are as a population. The differentiation characterization of ES cells was also conducted with different culture conditions of reduced serum and glucose concentrations both in the presence and absence of leukemia inhibitory factor (LIF) which prevents spontaneous differentiation, as well as at varied LIF concentrations and seeding densities. In addition, fundamental growth kinetic and metabolic profiles were obtained to get a more complete picture of how ES cells behave under these varied culturing conditions. The doubling time (t[sub]d) of R1 Oct4-GFP cell line was found to be 13 hours in LIF⁺ culture and 8 hours in culture with LIF addition after 7 days of LIF withdrawal, implying that cell proliferation rate is higher for cells receiving a sudden upregulation of genes controlling cell division through LIF addition. Although the upregulation of the genes is rapid, the downregulation of these genes through LIF withdrawal was found to take 6-7 days, while 3-4 days were required to downregulate the pou5f gene (which controls Oct4 expression). Higher concentration of LIF resulted in higher ES cell proliferation rate, but GFP⁺ expression was unaffected by(cont.) concentration. Higher seeding density resulted in greater improvement in GFP⁺ expression for LIF⁺ culture but lower non significant reduction in GFP⁺ expression in LIF⁻ culture. Low level of glucose in medium led to reduction in the rate of ES cellular mechanisms and lower Y[sub]lac/gluc (8-49 % versus 40-60 % in high glucose), but metabolic rates were consistent with cells grown in high glucose medium, implying more efficient glucose metabolism through oxidative phosphorylation. The level of serum in medium had no effect on GFP⁺ expression or cell proliferation rate in LIF⁺ cultures, but reduction in GFP⁺ expression level was higher and t[sub]d was longer in low-serum culture (71 [plus-minus] 33 hours versus 35 [plus-minus] 9 hours) in the absence of LIF.by Yasunori Hashimura.M.Eng
Difference in effects of end-plate potentials between procaine and lidocaine as revealed by voltage-clamp experiments.
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Elastic Bending Behavior of Aluminum Alloy Foam
No full textAbstractAluminum alloy foam has been an attractive material to be used in many engineering applications due to its novel properties and behaviors in combination with the light-weight structure. Many researches had been conducted to enable and explore more widespread engineering applications of this material; however, its mechanical responses are yet to be fully understood. The work presented in this paper is aimed at studying the elastic bending behavior of aluminum alloy foam by experimental investigations and theoretical analysis. From the experiments, the measured flexural moduli are found to be significantly larger than the corresponding Young's moduli. Moreover, the foam's stiffness equation introduced by Ashby et al. for the design-guide is found to be not suitable for estimation of the flexural moduli. The theoretical analysis was carried out to identify the mechanism responsible for generating the discrepancy. We found that the different in cell local-deformation under uniaxial loading and bending condition plays a prominent role in the discrepancy, where in particular, the effect of cell-face stretching was found to be dominant in bending condition
Estudo da formação de rebarbas no processo de furação
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnologicoInvestigação da formação de rebarbas na usinagem, mais precisamente na furação, com o objetivo de adequar o processo, visando a minimização das rebarbas. Estudo dos efeitos da velocidade de corte, do avanço e da geometria da broca sobre o tamanho e a forma das rebarbas produzidas. Experimentos realizados em chapas de alumínio 6063-O com 3 mm de espessura. Análise das rebarbas da saída do furo; por serem maiores, de mais difícil acesso, e conseqüentemente mais problemáticas em termos de facilidade de remoção. As brocas utilizadas nos experimentos são de aço rápido, com ângulos de ponta de 100º, 118º e 135º, e ângulos de hélice de 25º, 35º e 45º, todas com 10 mm de diâmetro. A avaliação das rebarbas é feita pela suas dimensões, pelo peso e pela forma que esta apresenta. Verifica-se a ocorrência de uma diminuição substancial no tamanho da rebarba quando são empregados avanços pequenos e quando se aumenta o ângulo de hélice da broca
Flexion-extension motion assistance using an upper limb motion-assist robot based on trajectory estimation of reaching movement
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