3,053 research outputs found
Introduction: Framing the methodology of justice, injustice and Brexit
No full textThis chapter explores, and attempts make more explicit, the diversity of methodological and analytical approaches within legal studies to Brexit as to its just or unjustness. It asks what are the diversity of perspectives and methodological approaches to Brexit and what do they tell us about the intellectual robustness of our study of Brexit? The chapter makes the case that legal issues of Brexit are challenging to explore because of different approaches to justice and injustice, and seeks to be more explicit about the existence and nature of these approaches in our study of Brexit
Recensione a: Alber J.,Fahey, T. and Saraceno C. (eds.) Hanbook of quality of life in the Enlarged European Union
No full textRecensione al volume: Alber J.,Fahey, T. and Saraceno C. (eds.) (2008) Hanbook of quality of life in the Enlarged European Union, Abindon: Routledge
Primary health care models and suitability for provision of e-services: an overview
No full textWe present an overview of the most frequently distributed types of primary health care (PHC) models of delivery across different countries and cultural environments. We summarise and describe most important definitions, principles of classification, attributes, necessary conditions (e.g., patient-management systems, electronic health records, ICT platforms) and organisation and key performance indicators (KPI) for functioning of the primary health care systems. We review and explore the suitability of different PHC models for provision of electronic (e-)services.</p
New simplified approach to the pooled analysis of calibration of clinical prediction rules for systematic reviews of validation studies
No full textAppropriateness of prescribing for childhood eczema: evidence from a community-based study
No full textData on dispensed prescriptions of topical corticosteroids and emollients were analysed in a population of 25 484 children aged ? 6 years in Tayside, Scotland. Over a 17-month period, 5818 (22.8%) children were prescribed a topical corticosteroid; half of this group, (2946; 50.6%) were not prescribed any emollient. In the group of children prescribed topical corticosteroids, 3505/5818 (60.2%) received combined preparations of topical corticosteroids with antimicrobials over this time period, and potent or very potent preparations were prescribed for 923/5818 (15.9%
Effects of centrifugation speed and freez-ing on the composition of ruminal bacterial samples collected from defaunated _TTS.DATE
No full textA concept for a long-term scalable bioengineering model of primary care
No full textWe present a concept for development of a unified bioengineering framework that consolidates efforts in extending the geographical boundaries and outreach of primary care in Ireland and ensure its long-term scalability. This framework encompasses infrastructures, devices, systems, techniques, materials, engineering practices and socio-technical set-ups for improved access, safety and quality of care at national and global levels. In particular, we address the development of special purpose solutions, technologies and devices for healthcare from a bioengineering perspective, within the wider healthcare and biotechnology agendas in Ireland
A simplified approach to the pooled analysis of calibration of clinical prediction rules for systematic reviews of validation studies
No full textObjective: Estimating calibration performance of clinical prediction rules (CPRs) in systematic reviews of validation studies is not possible when predicted values are neither published nor accessible or sufficient or no individual participant or patient data are available. Our aims were to describe a simplified approach for outcomes prediction and calibration assessment and evaluate its functionality and validity.Study design and methods: Methodological study of systematic reviews of validation studies of CPRs: a) ABCD2 rule for prediction of 7 day stroke; and b) CRB-65 rule for prediction of 30 day mortality. Predicted outcomes in a sample validation study were computed by CPR distribution patterns (“derivation model”). As confirmation, a logistic regression model (with derivation study coefficients) was applied to CPR-based dummy variables in the validation study. Meta-analysis of validation studies provided pooled estimates of “predicted:observed” risk ratios (RRs), 95% confidence intervals (CIs), and indexes of heterogeneity (I2) on forest plots (fixed and random effects models), with and without adjustment of intercepts. The above approach was also applied to the CRB-65 rule.Results: Our simplified method, applied to ABCD2 rule in three risk strata (low, 0–3; intermediate, 4–5; high, 6–7 points), indicated that predictions are identical to those computed by univariate, CPR-based logistic regression model. Discrimination was good (c-statistics =0.61–0.82), however, calibration in some studies was low. In such cases with miscalibration, the under-prediction (RRs =0.73–0.91, 95% CIs 0.41–1.48) could be further corrected by intercept adjustment to account for incidence differences. An improvement of both heterogeneities and P-values (Hosmer-Lemeshow goodness-of-fit test) was observed. Better calibration and improved pooled RRs (0.90–1.06), with narrower 95% CIs (0.57–1.41) were achieved.Conclusion: Our results have an immediate clinical implication in situations when predicted outcomes in CPR validation studies are lacking or deficient by describing how such predictions can be obtained by everyone using the derivation study alone, without any need for highly specialized knowledge or sophisticated statistics
Tony Fahey, Helen Russell & Christopher T. Whelan eds., Best of Times ? The Social Impact of the Celtic Tiger
No full textGuillaumond Julien. Tony Fahey, Helen Russell & Christopher T. Whelan eds., Best of Times ? The Social Impact of the Celtic Tiger. In: Études irlandaises, n°32 n°2, 2007. Les nouveaux irlandais, sous la direction de Karin Fischer et Anne Goarzin. pp. 214-215
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