2,122 research outputs found
P. Stanislaus De Backer, S. J., Institutiones Metaphysicae specialis, t. II et III : Psychologia
No full textFaelens Gaston. P. Stanislaus De Backer, S. J., Institutiones Metaphysicae specialis, t. II et III : Psychologia. In: Revue néo-scolastique. 12ᵉ année, n°46, 1905. pp. 279-280
P. Stanislaus De Backer, S. J., Institutiones Metaphysicae specialis, t. II et III : Psychologia
No full textFaelens Gaston. P. Stanislaus De Backer, S. J., Institutiones Metaphysicae specialis, t. II et III : Psychologia. In: Revue néo-scolastique. 12ᵉ année, n°46, 1905. pp. 279-280
A short history of the European Association of Preventive Cardiology (EAPC)
No full textDe Backer G, Perk J, Wood D, et al. A short history of the European Association of Preventive Cardiology (EAPC). European Journal of Preventive Cardiology . 2022: zwac027.The history of the EAPC is closely related to the history of the European Society of Cardiology (ESC). The ESC decided at the turn of the century to overcome the splitting into 27 topic related Working Groups with great differences in size and activities and to create a new organizational concept based on Associations, each having an official ESC scientific journal and an annual ESC connected congress. The European Association for Cardiovascular Prevention and Rehabilitation was built on the fundaments of epidemiology and prevention, exercise physiology, cardiac rehabilitation and sports cardiology. The official journal of the Association was launched in 2003 and the first EuroPRevent Congress was held in Athens in 2006. During the following years, the different interests of the founding working groups came closer together, which resulted in a name change of the Association into "European Association of Preventive Cardiology" and of the journal into "European Journal of Preventive Cardiology". The name change marked the migration of Preventive Cardiology to centre stage in the ESC. This document summarizes how and from where the EAPC started and where it stands now. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2022. For permissions, please email: [email protected]
't Hollandts Venezoen in Engelandt gebacken Wederleyt door d'Amsterdamse Pastey-Backer Tegen sijn Buyrman Brandt
No full textTiele: "Gesprek tussen Pasteybacker en (Geeraert) Brandt. Van den Venezoen zegt de eerste: "Sy seggen datse op de Singel gemengt, en op de Keysersgracht by de Heere straet gekneet, en in de Dirck-van-assens-steegh gebacken is".Knuttel, W.P.C. Catalogus van de pamfletten-verzameling berustende in de Koninklijke Bibliotheek, 10618Toegeschreven aan Joachim Oudaan of Pieter de GrootKolumnentitel: Buur-Praetjen Tusschen een Pastey-Backer,en sijn Buyrman Brandt, Klagende aen de selve over 't Bederf van sijn NeeringeKnuttel 10618Tiele, P. A. Bibliotheek van Nederlandsche pamfletten 1,3,6533STCN 86315726
Music Therapy Training:a Process to Develop the Musical and Therapeutic Identity of the Music Therapist
No full textReplication Data for: Metaphor analysis meets lexical strings: Finetuning the Metaphor Identification Procedure for quantitative semantic analyses
No full textDataset Abstract:
This is the data that serves as the basis for a methodological article which proposes and illustrates two ways to extend the Metaphor Identification Procedure in such a way as to allow it to capture (metaphorical) lexical strings, in addition to (simple) metaphor-related lexical units. It includes a sample of 25 linguistic metaphors which stem from a larger corpus compiled by the first author, between October 2021 and May 2023. The corpus contains newspaper articles published in the Spanish-language, US-based newspaper El Diario (the El Paso and Juárez local editions). These articles revolve around the DACA (Deferred Action for Childhood Arrivals program) immigration program and were published between November 2020 and May 2023.Article abstract:
Recent years have witnessed the development of the Metaphor Identification Procedure (MIP/VU), a step-by-step protocol designed to identify metaphorically-used words in discourse. However, MIP(VU)’s merits notwithstanding, the procedure poses a problem to scholars intending to use its output as the basis for a semantic field analysis involving a quantitative component. Depending on the research question, metaphor analysts may be interested in chunks of language situated above the procedure’s standardized level of analysis (i.e, the lexical unit), including phrases and sentences. Yet, attempts to decenter the method’s exclusive focus on metaphor-related words have been the target of critique, among others on the grounds of their lack of clear unit-formation guidelines and, hence, their inconsistent unit of analysis and measurement. Drawing on data derived from a Spanish-language US-based newspaper’s coverage of the migration program known as DACA (Deferred Action for Childhood Arrivals), this article describes challenges that analysts can run into when attempting to use a dataset containing atomized metaphor-related words as the input for subsequent quantitative semantic analyses. Its main methodological contribution consists in a proposal and illustration of two possible ways to extend the existing MIP(VU)-protocol in such a way as to allow it to catch metaphorical strings, on top of words, in a reliable and systematic manner. One approach is procedural, and entails formulating a-priori grouping-directives based on the research question(s). The other is exploratory, involving the ad hoc grouping of units and adding a descriptive parameter meant to keep track of grouping-decisions made by the analyst, thereby safeguarding transparency at all time
Konsthistoriepodden, avsnitt 35: Harriet Backer, Barndop i Tanum kyrka
No full textI detta poddavsnitt förenar vi våra forskningsintressen, 1800-talsmåleri och medeltida kyrkor: vi pratar om den norska konstnären Harriet Backers målning ”Barndop i Tanum Kyrka” från 1892. Vanligtvis finns konstverket att beskåda på Nasjonalmuseet i Oslo, men just nu kan man se det på den stora Harriet Backer-utställningen på Nationalmuseum i Stockholm. Harriet Backer är en av de mest kända norska konstnärerna. Hennes yrkeskarriär spänner över 50 år och en tid då konstvärlden ändrade sig radikalt för kvinnor. När Harriet Backer började sina konstnärliga studier på 1870-talet var det ett mansdominerat fält. Hon blev framgångsrik och erkänd, men hon var likväl “bara” en kvinna. Jens Thiis, som var direktör för Nasjonalgalleriet i Oslo från 1908-1941, skrev om henne i sin bok om norska målare och bildhuggare 1907: “Fröken Backer är i själva verket den av alla norska målarinnor som är mest née peintre [alltså: född till målare] och även i sina manliga kollegors lag intar hon en hög ställning som målare.” I poddavsnittet berättar vi mer om Harriet Backers karaktäristiska intima och självupplevda sätt att skildra norska kyrkorum som är unikt i den norska konsthistorien. Vi berättar hur interiörsgenren blev populär på 1800-talet och hur Backer anknöt till 1800-talets olika nationalromantiska skildringar av kyrkorummet eller psykologiserande närstudier av kyrkobesökare, men också den hårda kritiken hon mötte. Samspelet av färgerna, ljus och skuggan som skapar den stämningsfulla atmosfären i hennes målningar åstadkom hon genom sitt noggranna arbete på plats, t ex i den iskalla kyrkan i Tanum. Eftersom hon antog sig sina motiv på samma sätt som en friluftsmålare, kan man med all rätt kalla hennes målningar för ett “inomhus-friluftsmåleri”. Avsnittet handlar också om Harriet Backers konstnärliga utveckling från hennes tidiga måleri i Düsseldorfsskolans anda tills friluftsmåleriet och impressionismen satte sina spår på hennes naturalistiska färgmåleri under hennes år i Paris
Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene
No full textThe MAGE1 gene codes for an antigen recognized on melanoma cell line MZ2-MEL by autologous cytolytic T lymphocytes. It is expressed in a number of tumors of different histological origins, but not in normal tissues except in testis. The MAGE1 promoter region was analyzed by performing transient transfections in MZ2-MEL cells with luciferase reporter plasmids. A fragment extending from nucleotide -792 to +118 exhibited high transcriptional activity. By deletional analysis of this fragment, we identified five activating regions designated C, A, B', B, and D. The activity of region A depends on the presence of region B' and vice versa. Two inverted Ets motifs contained in regions B' and B were found to drive 90% of the activity of the MAGE1 promoter in MZ2-MEL cells. Electrophoretic mobility shift assays performed with a nuclear extract from MZ2-MEL cells and with competitor oligonucleotides containing an Ets consensus site showed that nuclear proteins bind to the Ets motif of regions B' and B. Similar experiments suggested that region A binds transcription factors of the Sp1 family. The MAGE1 promoter was found to exert transcriptional activity in tumor cells where the MAGE1 gene is not expressed, suggesting that other mechanisms, such as demethylation, may contribute to the tumor-specific expression of the gene
Averting a pandemic health crisis in Europe by 2020: what physicians need to know regarding cholesterol management
No full textBACKGROUND: Cardiovascular disease (CVD) represents a major cause of premature death, disability, and escalating healthcare costs throughout Europe. According to a recent report by the Stockholm Network (an independent European 'think tank'), major political, economic, social, and medical changes are urgently needed with respect to cholesterol management to help prevent CVD. METHODS: To identify key cholesterol management issues that practitioners should consider to help prevent an impending European health crisis, our collective experience of policies and practices relating to CVD and cholesterol management in our respective countries was consolidated and used to develop this commentary. RESULTS: Physicians and healthcare workers are uniquely positioned to make immediate and meaningful improvements in preventing and treating CVD if they recognize and address a handful of key clinical issues pertaining to cholesterol management. These issues include utilizing newer combination therapies and realizing the limitations of statins, improving compliance with cholesterol-lowering therapies, promoting a healthy lifestyle and diet, making treatment decisions based on patients' total CVD risk, fostering communication between primary and secondary providers, and soliciting governmental funding to implement disease management programmes. CONCLUSIONS: By promptly and effectively addressing these cholesterol management issues, physicians and other healthcare professionals have an unprecedented opportunity to help reduce CVD in Europe to lessen the personal, social, and economic impact of this devastating disease
How sample handling distorts telomere studies
No full textTelomere length (TL) is investigated as a biomarker for aging and disease-susceptibility, but
measurement using quantitative polymerase chain reaction (qPCR) faces challenges in accuracy
and reproducibility. The potential impact of pre-analytical factors on TL measurements remains
underexplored. We evaluated the impact of delayed blood processing, a typical feature in population
studies. Blood samples from 35 adults were processed for buffy coat extraction either immediately or
kept at 4 °C and processed after three and seven days (total n=105). After processing, samples were
stored at -80 °C. Relative TL was measured via qPCR and expressed as T/S ratio. Strikingly, delayed
blood processing led to a significant increase in TL: the mean T/S ratio was 0.886±0.205 at day 0, rising
to 1.022±0.240 at day 3 (p=0.03) and to 1.190±0.205 at day 7 (p<0.001), corresponding to increases
of 15% and 34%, respectively. Notably, TL correlated inversely with DNA integrity. These findings
underscore the critical impact of delayed sample processing on TL measurements, emphasizing the
need for consistent pre-analytical protocols to ensure accurate and reliable research outcomes. The
impact of our findings is considerable as it may overshadow not only previously reported results but
also real biological differences in TL between studied groups of patients.This work is funded in part by the Research Foundation Flanders (grant number G072022N to JDB and grant
number 12X9623N to DSM)
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