420 research outputs found
Adaptive Uncertainty-Penalized Model Selection for Data-Driven PDE Discovery
No full textThanasutives P., Morita T., Numao M., et al. Adaptive Uncertainty-Penalized Model Selection for Data-Driven PDE Discovery. IEEE Access 12, 13165 (2024); https://doi.org/10.1109/ACCESS.2024.3354819.We propose a new parameter-adaptive uncertainty-penalized Bayesian information criterion (UBIC) to discover the stable governing partial differential equation (PDE) composed of a few important terms. Since the naive use of the BIC for model selection yields an overfitted PDE, the UBIC penalizes the found PDE not only by its complexity but also by its quantified uncertainty. Representing the PDE as the best subset of a few candidate terms, we use Bayesian regression to compute the coefficient of variation (CV) of the posterior PDE coefficients. The PDE uncertainty is then derived from the obtained CV. The UBIC follows the premise that the true PDE shows relatively lower uncertainty when compared with overfitted PDEs. Thus, the quantified uncertainty is an effective indicator for identifying the true PDE. We also introduce physics-informed neural network learning as a simulation-based approach to further validate the UBIC-selected PDE against the other potential PDE. Numerical results confirm the successful application of the UBIC for data-driven PDE discovery from noisy spatio-temporal data. Additionally, we reveal a positive effect of denoising the observed data on improving the trade-off between the BIC score and model complexity
Lectin binding patterns in normal, metaplastic, and neoplastic gastric mucosa.
No full text We investigated lectin binding patterns on tissue specimens of normal and metaplastic gastric surface mucosae, gastric adenomas, and intestinal and diffuse-type gastric carcinomas. Compared with normal gastric mucosa, metaplastic mucosa exhibited an increase of ConA binding and decreases of WGA, PNA, UEA-1, and DBA binding in the cytoplasm, and decreases of ConA, PNA, and UEA-1 binding at the luminal surface. Intestinal carcinomas were similar to metaplastic gastric surface mucosa in ConA, WGA, and UEA-1 binding in the cytoplasm, while diffuse-type carcinomas were similar to normal gastric mucosa in WGA and UEA-1 binding in the cytoplasm. Adenomas were similar to intestinal carcinomas in ConA and UEA-1 binding in the cytoplasm, but were different from intestinal carcinomas in Con A and UEA-1 binding at the luminal surface. For UEA-1, normal and metaplastic gastric surface mucosae did not show a significant difference between the blood type A, AB, B group and the O group. Intestinal and diffuse carcinomas and adenomas also did not show such a difference between the blood groups. For DBA, normal gastric surface mucosa showed a significant difference between the blood type B, O group and the A, AB group. Normal gastric mucosa of the blood type A, AB group was frequently positive for DBA binding in the cytoplasm and at the luminal surface. Metaplastic mucosa did not show a significant difference between the blood groups. Intestinal and diffuse-type carcinomas and adenomas also did not show a difference between the blood groups. DBA binding in the cytoplasm of intestinal carcinomas and adenomas was more frequently positive than that of normal and metaplastic mucosae, except for normal gastric mucosa of the blood type A, AB group. Compared with diffuse-type carcinomas, intestinal carcinomas were accompanied by a significant increase of ConA binding and decreases of WGA and PNA binding in the cytoplasm. </jats:p
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No full textOptimum utilization of fly ash for achieving properties of high performance concrete
No full textCoal fly ash is obtained as final product by combustion of coal in power plants during process of producing electrical energy. In Kosovo electricity production and its generation is dependent largely based on coal burning power plants. Currently 97% of electrical energy is produced only from coal and based on reserves of this mine and the situation of other resources it seems that for long time coal will be the only source of energy. As result average of coal fly ash is around 1,16million t/year. [1] So, considering this situation, idea of substituting different percentage of cement with coal fly ash in producing concrete will help to reach the point of recycling waste material, reducing amount of cement production, increasing quality of concrete, protecting environment and it has positive effect in economical aspect too. The literature is rich in publications regarding influence of fly ash in concrete, especially for low-calcium fly ash (less than 10% of CaO) [2-4] but suitability of high-calcium fly ash in concrete still is considered with skepticism.[5] These happen especially related to chemical compositions high content of CaO and SO3 can effect volume stability and concrete stability.[6,7,8] Following this approach, an experimental investigation of quality of concrete with different percentage of content of high-calcium fly ash is carried out. In focus is high performance concrete C 50/60 and all work took place in concrete lab according to EN 206-1
INFLUENCE OF PHYSICAL PROPERTIES OF WATER BARRIER PENETRANTS ON PERMEABILITY INTO MORTAR
No full textEvaluation of cutoff scores for the Parkinson's disease sleep scale-2
No full textBackgroundThe Parkinson's Disease Sleep Scale (PDSS)-2 is a recently developed tool for evaluating disease-related nocturnal disturbances in patients with Parkinson's disease (PD). However, its cutoff score has not been clinically assessed. We determined the optimal cutoff score of the Japanese version of the PDSS-2. MethodsPatients with PD (n=146) and controls (n=100) completed the PDSS-2 and the Pittsburgh Sleep Quality Index (PSQI). Poor sleepers were defined as having global PSQI scores >5. Optimal cutoff scores for determining poor sleepers were assessed using the receiver operating characteristic curve. ResultsA PDSS-2 total score 14 exhibited 82.0% sensitivity and 70.6% specificity, whereas a PDSS-2 total score 15 provided 72.1% sensitivity and 72.9% specificity in distinguishing poor sleepers (PSQI score >5) from good sleepers (PSQI 5). Nocturnal disturbances were more frequently observed in patients with PD than in controls (PDSS-2 total score 14 or 15; 51.4% vs 20%; 45.9% vs 19%). Nocturnal disturbances were associated with higher Hoehn and Yahr stages and Unified Parkinson's Disease Rating Scale motor scores, impaired quality of life, daytime sleepiness, and depressive symptoms. ConclusionWe suggest that PDSS-2 total scores 15 are useful for detecting poor sleepers among patients with PD
Comment on Numao et al.: Clinical correlates of serum insulin-like growth factor-1 in patients with Parkinson's disease, multiple system atrophy and progressive supranuclear palsy.
No full text[no abstract available
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