4 research outputs found
RELATIONSHIP BETWEEN THE ACNE CLINICAL COURSE AND SEVERITY AND THE STATE OF MICROBIOTA OF THE SKIN AND LARGE INTESTINE
No full textA high incidence of acne, tendency to its chronic course with the formation of resistance to treatment and frequent development of deep forms determine an important medical and social significance of the problem.
Aim. To study and evaluate the degree of changes in the microbiocenosis of the skin and large intestine in patients with acne, depending on their clinical course.
Materials and Methods. We examined 85 patients with acne, aged 18 to 45 years, 49 (57.65±5.36%) women, 36 (42.35±5.36%) men and 35 apparently healthy persons who made up the control group. The composition of microbiota of the skin and large intestine was examined using a bacteriological method.
Results and Discussion. It was found that there is a significantly lower content of bifidobacteria and lactobacilli, bacterioids and total E. coli count in the large intestine in patients with acne associated with a higher amount of E. coli with enzyme properties, conditionally pathogenic enterobacteria, enterococci and fungi of the genus Candida. When using Friedman's non-parametric analysis of variance, it was found that there is a statistically significant difference between the frequency of detection of normocenosis and the stage of the large intestinal dysbiosis and the development of clinical forms of acne. At that, normocenosis was detected more often in patients with comedonal acne, while papular and nodular acne occurred more often in patients with manifestations of different stages of dysbiosis. An increase in seeding with associations of the alpha-hemolytic streptococcus + Staphylococcus haemolyticus + Micrococcus, beta-hemolytic streptococcus + Staphylococcus aureus + E.Coli + Candida albicans and a significant increase in the growth of alpha-hemolytic streptococcus, Staphylococcus haemoliticus and Staphylococcus aureus were found in the microbiocenosis of the skin in patients with acne. At that, all of the above microorganisms were not cultured in the patients of the control group.
Conclusion. The qualitative and quantitative changes in the parameters of microbiocenosis of the skin and large intestine, which depend on the clinical course of dermatosis, were found in the examined patients with acne. This indicates the need for additional examination of such patients with the aim of prescribing a pathogenetically substantiated therapy
Cechy metrologiczne do określania stężenia cholesterolu, trójglicerydów i fosfolipidów w celu wykrywania łuszczycy
No full textThe article is dedicated to the study of promising methods for determining the concentration of cholesterol, triglycerides, and phospholipids for the detection of psoriasis. It demonstrates that when interacting with cholesterol and triglycerides, the cholesteric-nematic mixture alters its spectral characteristics, in particular, which leads to a wavelength shift in the direction of the long-wavelength region. It is also shown that the liquid crystal mixture can serve as a sensitive element in an optical sensor for cholesterol and triglycerides and be one of the rapid diagnostic methods for detecting psoriasis.Artykuł poświęcony jest badaniu obiecujących metod określania stężenia cholesterolu, trójglicerydów i fosfolipidów w celu wykrycia łuszczycy. Wykazano, że podczas interakcji z cholesterolem i trójglicerydami mieszanina cholesterol-nematyczna zmienia swoją charakterystykę spektralną, w szczególności powodując przesunięcie minimalnej długości fali w kierunku obszaru o dużej długości fali. Wykazano również, że mieszanina ciekłych kryształów może służyć jako element czujnikowy w optycznym czujniku cholesterolu i trójglicerydów i być jedną z szybkich metod diagnostycznych do wykrywania łuszczycy
(Ukrainian Citizen and refugee electronic support in Respiratory diseases, Allergy, Immunology and Dermatology) action plan
No full textEight million Ukrainians have taken refuge in the European Union. Many have asthma and/or allergic rhinitis and/or urticaria, and around 100,000 may have a severe disease. Cultural and language barriers are a major obstacle to appropriate management. Two widely available mHealth apps, MASK-air® (Mobile Airways Sentinel NetworK) for the management of rhinitis and asthma and CRUSE® (Chronic Urticaria Self Evaluation) for patients with chronic spontaneous urticaria, were updated to include Ukrainian versions that make the documented information available to treating physicians in their own language. The Ukrainian patients fill in the questionnaires and daily symptom-medication scores for asthma, rhinitis (MASK-air) or urticaria (CRUSE) in Ukrainian. Then, following the GDPR, patients grant their physician access to the app by scanning a QR code displayed on the physician's computer enabling the physician to read the app contents in his/her own language. This service is available freely. It takes less than a minute to show patient data to the physician in the physician's web browser. UCRAID-developed by ARIA (Allergic Rhinitis and its Impact on Asthma) and UCARE (Urticaria Centers of Reference and Excellence)-is under the auspices of the Ukraine Ministry of Health as well as European (European Academy of Allergy and Clinical immunology, EAACI, European Respiratory Society, ERS, European Society of Dermatologic Research, ESDR) and national societies
UCRAID (Ukrainian Citizen and refugee electronic support in Respiratory diseases, Allergy, Immunology and Dermatology) action plan
No full text25812595Eight million Ukrainians have taken refuge in the European Union. Many have asthma and/or allergic rhinitis and/or urticaria, and around 100,000 may have a severe disease. Cultural and language barriers are a major obstacle to appropriate management. Two widely available mHealth apps, MASK-air® (Mobile Airways Sentinel NetworK) for the management of rhinitis and asthma and CRUSE® (Chronic Urticaria Self Evaluation) for patients with chronic spontaneous urticaria, were updated to include Ukrainian versions that make the documented information available to treating physicians in their own language. The Ukrainian patients fill in the questionnaires and daily symptom-medication scores for asthma, rhinitis (MASK-air) or urticaria (CRUSE) in Ukrainian. Then, following the GDPR, patients grant their physician access to the app by scanning a QR code displayed on the physician's computer enabling the physician to read the app contents in his/her own language. This service is available freely. It takes less than a minute to show patient data to the physician in the physician's web browser. UCRAID—developed by ARIA (Allergic Rhinitis and its Impact on Asthma) and UCARE (Urticaria Centers of Reference and Excellence)—is under the auspices of the Ukraine Ministry of Health as well as European (European Academy of Allergy and Clinical immunology, EAACI, European Respiratory Society, ERS, European Society of Dermatologic Research, ESDR) and national societies.781
