50,300 research outputs found
Class fields from the fundamental Thompson series of level N = o(g)
No full textThompson series is a Hauptmodul for a genus zero group which lies between Gamma(0)(N) and its normalizer in PSL2(R) ([1]). We construct explicit ring class fields over an imaginary quadratic field K from the Thompson series T-g(alpha) (Theorem 4), which would be an extension of [3], Theorem 3.7.5 (2) by using the Shimura theory and the standard results of complex multiplication. Also we construct various class fields over K, over a CM-field K(zeta(N) + zeta(N)(-1)), and over a field K(zeta N). Furthermore, we find an explicit formula for the conjugates of T-g (alpha) to calculate its minimal polynomial where alpha(is an element of h) is the quotient of a basis of an integral ideal in K
Missing equation in Piketty’s r-g theory
No full textAlthough Thomas Piketty has revolutionized our understanding of inequality, logic behind his r-g theory is not developed formally in his researches. The present paper, by finding out the missing part of Piketty’s r-g theory, attempts to construct a model to show the condition where β (capital/income ratio) increases over time when r (rate of return on capital) is greater than g (growth rate of output). It is revealed that necessary and sufficient condition for the r-g theory is SY(t)=CF(t). That is, savings (left hand side) are equal to the consumption using financial capital (right hand side). We also reveal that the problem is not in the Second Fundamental Law of Capitalism, but in the formulation of capital accumulation dynamics. Furthermore, it is demonstrated that the two Fundamental Laws of Capitalism are not necessary for deriving the r-g theory
Missing equation in Piketty’s r-g theory
No full textAlthough Thomas Piketty has revolutionized our understanding of inequality, logic behind his r-g theory is not developed formally in his researches. The present paper, by finding out the missing part of Piketty’s r-g theory, present a complete version of Piketty’s framework. It is revealed that necessary and sufficient condition for the r-g theory is SY(t)+AY(t)=CF(t). That is, savings in a broad sense (left hand side) is equal to the consumption using financial capital (right hand side). We also reveal that the problem is not in the Second Fundamental Law of Capitalism, but in the formulation of capital accumulation dynamics. Furthermore, it is demonstrated that the two Fundamental Laws of Capitalism are not necessary for deriving the r-g theory
The dialogue between the author and the hero in the “Notes” of G. R. Derzhavin
No full textВ центре внимания автора статьи «Записки» Г. Р. Державина, представляющие по своей сути его автобиографию. Труд этот был создан на закате жизни, он включает все важнейшие события жизни Г. Р. Державина, поэта и государственного деятеля. Рассказ ведется от третьего лица, что придает особую атмосферу повествованию, выстраивается своеобразный диалог между автором и героем, все это и является предметом исследования автора статьи.The focus of the author of the article “Notes” G. R. Derzhavin, representing in essence his autobiography. This work was created at the end of his life; it includes all the most important events in the life of G. R. Derzhavin, poet and statesman. The story is told in a third person, which gives a special atmosphere to the story, a certain dialogue emerges between the author and the hero, all this is the subject of the author's research
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Level maintenance for Tank 101-SY mitigation-by-mixing test
No full textThis document provides the procedure to be followed to implement the requirements of the Mixer Pump Long-Term Operations Plan for Tank 241-SY-101 Mitigation, WHC-SD-WM-PLN-081. The test is divided into 2 distinct sequences, named Single Position Pump Run and Tank Sweep. Instructions for all sequences are defined within the procedure. All safety requirements as defined in LA-UR-92-3196, A Safety Assessment for Proposed Mixing Operations to Mitigate Episodic Gas Releases in Tank 241-101-SY have been implemented into this procedure
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Criticality safety analysis of Hanford Waste Tank 241-101-SY
No full textAs part of a safety assessment for proposed pump mixing operations to mitigate episodic gas releases in Tank 241-101-SY at the Hanford Site, Richland, Washington, a criticality safety analysis was made using the Sn transport code ONEDANT. The tank contains approximately one million gallons of waste and an estimated 910 G of plutonium. the criticality analysis considers reconfiguration and underestimation of plutonium content. The results indicate that Tank SY-101 does not present a criticality hazard. These methods are also used in criticality analyses of other Hanford tanks
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A biomarker-directed phase 2 trial of SY-1425, a selective retinoic acid receptor alpha agonist, in adult patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)
No full textTPS7071
Background: SY-1425 (tamibarotene) is an orally available, synthetic retinoid approved in Japan for the treatment of relapsed/refractory (R/R) APL. SY-1425 is a more potent and selective retinoic acid receptor alpha (RARα) agonist with improved pharmacologic properties compared to all-trans retinoic acid (ATRA) including increased half-life and lack of metabolism by CYP26A1 resulting in extended relative exposures. SY-1425 binding to RARα relieves pathogenic repression of myeloid differentiation. Super-enhancers associated with RARA and upregulation of RARA expression correlate with increased sensitivity to SY-1425 in vitro and predict for response to SY-1425 with induced differentiation and reduced proliferation in RARA-high PDX AML models, but not in RARA-low models. SY-1425 also induces the RARα target gene DHRS3 in RARA-high AML cell lines. This study is designed to demonstrate pharmacodynamic (PD) and clinical effects of SY-1425 in non-APL AML and MDS patients (pts) positive for the RARA super-enhancer associated biomarker or exploratory RARA pathway biomarker, IRF8. Methods: This study is enrolling pts with R/R AML, R/R higher-risk MDS, newly-diagnosed AML ≥60 yrs unlikely to respond to or tolerate standard therapy, and transfusion dependent lower-risk MDS pts without del 5q who are unlikely to respond to or have failed ESAs. Pts must be biomarker positive based on centralized testing of tumor cells from blood. All pts receive SY-1425 at 6 mg/m
2
/day PO with continuous twice daily dosing. Primary objectives are to characterize the activity of SY-1425 by ORR in AML and higher-risk MDS pts or transfusion independence in lower-risk MDS pts. Secondary objectives include event-free and relapse-free survival, duration of response, overall survival, hematologic improvement and safety. PD evaluation includes induction of DHRS3 and expression of myeloid differentiation markers. Target enrollment is 80 pts. This trial opened in September 2016. Through a protocol amendment, SY-1425 treatment in combination with azacitidine will also be evaluated. ClinicalTrials.gov identifier: NCT02807558
Gravastars in f(R, G) gravity
No full textThis paper is focused on the study of gravitational vacuum stars or, briefly, gravastars in f(R, G) gravity, where R and G stand for the Ricci scalar and Gauss–Bonnet invariant term, respectively. Due to the involvement of highly non-linear differential equations, solutions are found by using some appropriate numerical techniques. The main structure of gravastars has been discussed according to core, shell, and exterior regions for a well-known f(R, G) gravity cosmological model. Mass–radius evolution is described graphically for the considered gravastar, and it is shown that the mass is directly proportional to the radius.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author
Introduction: Starring the Author
No full textLiterary celebrity is by now a familiar feat of contemporary literary culture, but it continues to raise complex questions about the history and development of fame, the interplay between the cultural marketplace and the official culture of critics and the canon, and the relation between authorial agency and public appropriation. This introduction addresses these questions by approaching literary celebrity as a merging of two discursive constructions: the celebrity-function and the author-function. By combining insights from celebrity studies, literary history and cultural memory studies, the introduction conceptualizes literary celebrity as a discursive construction with several variables, such as the author’s self-presentation, the circulation of his public identity, changing opinions on literature and writership, and the public afterlife of the author’s image
Spherically symmetric solution of f(R,G) gravity at low energy
No full textThe weak-field and slow-motion limit of f(R,G) gravity is developed up to (v/c)(4) order in a spherically symmetric background. Considering the Taylor expansion of a general function f around vanishing values of R and G, we present general vacuum solutions up to (v/c)(4) order for the gravitational field generated by a ball-like source. The spatial behaviors at (v/c)(2) order are the same for f(R,G) gravity and f(R) gravity, and their corresponding real valued static behaviors are presented and compared with the one in general relativity. The static Yukawa-like behavior is proved to be compatible with the previous result of the most general fourth-order theory. At (v/c)(4) order, the static corrections to the Yukawa-like behavior for f(R,G) gravity, f(R) gravity, and the Starobinsky gravity are presented and compared with the one in general relativity.National Natural Science Foundation of China [11120101004, 11475006]SCI(E)[email protected]; [email protected]
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