4,652 research outputs found
Swathi Reddy
No full textSwathi Reddy
Student and 2010 alumnahttps://sophia.stkate.edu/catherineportrait/1039/thumbnail.jp
Supramolecular chirality: a caveat in assigning the handedness of chiral aggregates
No full textThe handedness of a supramolecular chiral aggregate is often assigned based on the sign of circular dichroism spectra, adopting the exciton chirality method. However, the method does not properly account for the nature of intermolecular interactions. We introduce a generalized picture on the use of the sign of chiral signals in determining the helicity of chiral aggregates, rooted in the exciton model, supported by TD-DFT results
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Semantic Complexity In Treatment Of Naming Deficits In Aphasia: Evidence From Well-Defined Categories
No full textPurpose: Our previous work on manipulating typicality of category exemplars during treatment of naming deficits has shown that training atypical examples generalizes to untrained typical examples but not vice versa. In contrast to natural categories that consist of fuzzy boundaries, well-defined categories (e.g., shapes) have rigid category boundaries. Whether these categories illustrate typicality effects similar to natural categories is under debate. The present study addressed this question in the context of treatment for naming deficits in aphasia. Methods: Using a single-subject experiment design, 3 participants with aphasia received a, semantic feature treatment to improve naming of either typical or atypical items of shapes, while generalization was tested to untrained items of the category. Results: For 2 of the 3 participants, training naming of atypical examples of shapes resulted in improved naming of untrained typical examples. Training typical examples in 1 participant did not improve naming of atypical examples. All 3 participants, however, showed weak acquisition trends. Conclusions: Results of the present study show equivocal support for manipulating typicality as a treatment variable within well-defined categories. Instead, these results indicate that acquisition and generalization effects within well-defined categories such as shapes are overshadowed by their inherent abstractness.Communication Sciences and Disorder
Orbital relapse of retinoblastoma in patients with high-risk histopathology features
No full textAim: To describe the clinical picture of orbital relapse of retinoblastoma following uncomplicated enucleation. Methods: Case series of two patients with group E retinoblastoma with high-risk features on histopathology, namely, post-laminar optic nerve extension in one patient, and massive choroidal tumor infiltration in the other. Neither of them received adjuvant chemotherapy post enucleation. Results: Both patients had orbital relapse of tumor within 4 months from enucleation, manifesting as implant migration and unstable conformer. Systemic chemotherapy and external beam radiotherapy to the orbit resulted in complete tumor regression. Both patients were tumor free at the last follow up. Conclusion: Implant migration post enucleation should raise the suspicion for orbital relapse of retinoblastoma. High-risk histopathology features should increase the alert in an otherwise uncomplicated enucleation for retinoblastoma
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