3 research outputs found
Gegar Budaya di Era New Normal
No full textPenelitian dengan judul “Gegar Budaya Di Era New Normal” dilatar belakangi oleh kemunculan istilah new normal di masa pandemi ini yang menyebabkan masyarakat mengalami gegar budaya dan “dipaksa” untuk beradaptasi dengan kebiasaan baru di era new normal tersebut. Penelitian ini berfokus pada bagaimanakah pengalaman adaptasi masyarakat Kota Kupang dalam menghadapi gegar budaya di era new normal dengan tujuan untuk menganalisis pengalaman dan pemaknaan masyarakat kota Kupang dalam menghadapi gegar budaya di era new normal. Metode penelitian adalah fenomenologi. Hasil penelitian menunjukkan bahwa pada umumnya pengalaman adaptasi masyarakat di era new normal ini adalah mereka mengalami stress dan perasaan tersiksa karena kebiasaan-kebiasaan baru di era new normal yang terjadi karena masyarakat dihadapkan dengan kebiasaan-kebiasaan baru yang berbeda dengan kebiasaan-kebiasaan sebelumnya dan interaksi yang harusnya bisa berlangsung tatap muka harus dilakukan melaui media sehingga pada era new normal muncul ketergantungan terhadap teknologi. Namun pada akhirnya mereka harus menerima dan mulai terbiasa dan menyeseuaikan diri dengan hal kondisi tersebut. Selain itu juga berkaitan dengan pemaknaan masyarakat tentang gegar budaya di era new normal terdapat dua makna yang diberikan masyarakat yaitu new normal meningkatkan pola hidup sehat masyarakat, new normal sebagai sebuah keniscayaan, dan new normal semakin menyadarkan manusia sebagai makhluk yang saling membutuhkan
Pengembangan Media Promosi Kesehatan Tentang Isolasi Mandiri Bagi Orang Positif Covid-19
No full textPasien COVID-19 saat dinyatakan positif dan direkomendasikan untuk melakukan isolasi mandiri perlu dibekali dengan pengetahuan yang cukup tentang teknik pelaksanaan isolasi mandiri. Tujuan dari penelitian ini adalah mengembangan produk video sebagai media promosi kesehatan tentang isolasi mandiri bagi orang positif Covid-19. Metode yang digunakan dalam penelitian ini menggunakan model pengembangan “The Four Phase Media Development Model to Tell Your Research Story”. Penelitian ini merupakan penelitian Research and Development di mana penelitian ini menitikberatkan pada pengembangan video. Terdapat 4 fase yang diterapkan dalam pengembangan video tersebut yaitu fase penjajakan, fase pengembangan, fase rilis dan fase review. Semua Fase ini didiskusikan oleh informan dalam tahapan Focus Group Discussion (FGD). Secara garis besar penelitian ini mengangkat cerita pasien isolasi mandiri yang mempunyai latar belakang ekonomi lemah dan merupakan tulang punggung keluarga. Gaya pendekatan yang digunakan adalah pendekatan soft approach di mana informasi atau pesan kesehatan yang disampaikan dikemas sehalus dan sesederhana mungkin sehingga tidak ada kesan menggurui. Masyarakat sebagai audiens akan lebih mudah untuk dipengaruhi apabila ada keberpihakan pada masyarakat. Harapannya pesan kesehatan yang dikemas dalam video ini bisa memberikan dampak kognitif, afektif dan konatif. Selain itu, audiens yang terpapar pesan kesehatan melalui video diharapkan menjadi agent of change terkait upaya penanggulangan Covid-19
Obtenção de extrato de erva baleeira (Cordia verbenacea D.C.) por diferentes técnicas: medida da atividade biológica, modelagem matemática e determinação do equilíbrio de fases
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Alimentos.A erva baleeira (Cordia verbenacea) é uma planta da Família das Borraginaceae, encontrada nas restingas marítimas de quase todo o litoral brasileiro, sendo mais comumente encontrada no trecho compreendido entre os Estados de Santa Catarina e São Paulo. Devido ao seu perfil de composição, a erva baleeira possui propriedades antiinflamatória e cicatrizante sendo indicada para o tratamento de reumatismo, artrite reumatóide, tendinite, dores lombares e musculares e nevralgias. Os compostos da classe dos sesquiterpenos encontrados em seus extratos como a-humuleno e trans-cariofileno são os principais responsáveis pela sua atividade antiinflamatória. Assim, o presente trabalho tem como objetivo avaliar a qualidade dos extratos de erva baleeira obtidos a partir da tecnologia supercrítica através da comparação, em termos de rendimento de processo, composição dos extratos e atividade biológica, com os extratos obtidos a partir das técnicas convencionais de extração (maceração seguida de fracionamento com solventes orgânicos, extração soxhlet e hidrodestilação) e também com o uso de etanol e acetato de etila como co-solventes junto à ESC. Os extratos supercríticos de erva baleeira foram obtidos numa faixa de pressão de 100 a 300 bar e temperatura de 30, 40 e 50ºC com densidade do solvente variando de 0,385 a 0,948 g/cm3 sendo o maior rendimento de 5,0% para a condição de extração de 300 bar e 50ºC. Foram utilizados solventes orgânicos de diferentes polaridades na extração convencional como: hexano, diclorometano, acetato de etila, etanol, acetona e misturas aquosas de 25 e 50% (etanol/água). O etanol e o acetato de etila foram utilizados nas concentrações de 2, 5 e 8% em massa como co-solventes na ESC, proporcionando rendimentos de até 8,6%. Foram identificados importantes compostos nos extratos de erva baleeira como a-humuleno, trans-cariofileno, espatulenol, cariofileno óxido, b-sitosterol e artemetina. Também foi avaliada, através do método DPPH (2,2-difenil-1-picrilhidrazil), método ABTS (2,2#-azino-bis-(3-etil-benzotiazolna-6-ácido sulfônico), radical ânion superóxido e proteção contra a peroxidação lipídica a atividade antioxidante dos extratos obtidos com as diferentes tecnologias. O conteúdo de compostos fenólicos presente nos extratos foi determinado através do método de Folin-Ciocalteau. A erva baleeira se mostrou uma importante fonte de compostos com atividade antioxidante com destaque para os extratos: fração acetato de etila da maceração, misturas aquosas etanol/água e extrato acetato de etila da soxhlet que apresentaram as maiores capacidades antioxidantes. A atividade antimicrobiana foi avaliada e os extratos supercríticos mostraram forte inibição antimicrobiana principalmente contra bactérias Gram-positivas com destaque para o extrato obtido com CO2 puro a 30ºC e 300 bar. Para a descrição da cinética de extração do sistema extrato de erva baleeira + CO2 supercrítico foram empregados diferentes modelos de transferência de massa apresentados na literatura. O modelo de Sovová (1994) foi o que melhor se ajustou aos dados experimentais e a convecção se mostrou como principal mecanismo de transferência de massa e a difusão como fator limitante. Foi investigado experimentalmente o comportamento de fases dos sistemas binários contendo a-humuleno + CO2 e trans-cariofileno + CO2 e do sistema ternário formado por a-humuleno + trans-cariofileno + CO2, através do método estático sintético. Os resultados experimentais obtidos no estudo do equilíbrio de fases apresentaram transições de fases do tipo líquidovapor, líquido-líquido e líquido-líquido-vapor. Cordia verbenacea is a plant from the Borraginaceae family, widely find along the southeastern coast of Brazil, especially between the states of Santa Catarina and São Paulo. Due to its composition profile, Cordia verbenacea presents anti-inflammatory and healing properties, being indicated for treatment of rheumatism, rheumatoid arthritis, tendonitis, muscle and back pain and neuralgia. The compounds from the sesquiterpene class present in Cordia verbenacea extracts, such as a-humulene and trans-caryophyllene, are the main responsible for its antiinflammatory activity. Therefore, the aim of this study is to evaluate the quality of Cordia verbenacea extracts obtained by supercritical technology and compare, in terms of process yield, extracts composition and biological activity, with extracts obtained by conventional extraction techniques (maceration followed by fractionation with organic solvents, soxhlet extraction and hydrodistillation). The supercritical method was also improved by using ethanol and acetate ethyl as co-solvents. The supercritical extracts of Cordia verbenacea were obtained in a range of pressure from 100 to 300 bar and 30, 40 and 50°C of temperature with density of solvent varying from 0.385 a 0.948 g/cm3, being the largest extraction yield of 5.0% for the extraction condition of 300 bar and 50°C. The organic solvents of different polarity, used in conventional methods were: hexane, dichloromethane, ethyl acetate, ethanol, acetone and aqueous mixtures of 25 and 50% (ethanol / water). Ethanol and ethyl acetate were used in concentrations of 2.5 and 8% in mass as co-solvents in the supercritical extraction, providing yields up to 8.6%. Relevant compounds were identified in extracts of Cordia verbenacea as a-humulene, trans-caryophyllene, spathulenol, caryophyllene oxide, b-sitosterol and artemetin. The potential of the extracts were evaluated by the methods DPPH (2,2 - diphenyl - 1 - picrylhydrazyl), ABTS (2,2#- azinobis - 3 - ethylbenzothiazoline 6 - ulfonate), superoxide anion radical and protection against lipid peroxidation, in order to detect the antioxidant activity of extracts obtained by the different extraction technologies. The content of phenolic compounds present in the extracts was determined by the method of Folin-Ciocalteau. Cordia verbenacea has showed itself an important source of compounds with antioxidant activity, especially for the ethyl acetate fraction (maceration), ethanol/water mixtures and ethyl acetate from soxhlet method which presented the highest antioxidant capacity. The antimicrobial activity was evaluated and the supercritical extracts showed high antimicrobial inhibition, especially against gram-positive bacteria with emphasis to the extract obtained by CO2 at 30ºC and 300 bar. The kinetic description of the system Cordia verbenacea + supercritical CO2 was performed by different mass transfer models, presented in literature. The Sovová (1994) model show the best adjustment with experimental data and the convection was indicated as the main mass transfer mechanism, with diffusion as a limiting factor. The phase behavior was investigated for the binary systems containing a-humulene + CO2 and trans-caryophyllene + CO2 and for the binary system formed by a-humulene + trans-caryophyllene + CO2, through the static synthetic method. The experimental results obtained in the study of equilibrium phases showed transition of phases of the type liquid-vapour, liquid-liquid and iquid-liquid-vapour
