1,721,247 research outputs found

    Sutherland, I, VX39328

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/420060Surname: SUTHERLAND. Given Name(s) or Initials: I. Military Service Number or Last Known Location: VX39328. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 39150.244640 Item: [2016.0049.52321] "Sutherland, I, VX39328

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Countercurrent chromatography of proteins using aqueous two-phase systems

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    This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The biotechnology industry requires high - capacity protein manufacturing processes that retain protein functionality. Large - scale countercurrent J- type centrifuges have been developed by the Brunel Institute for Bioengineering that successfully purify small organic molecules using aqueous - organic phase systems. Aqueous two - phase systems (ATPS) have been used historically to purify bio-molecules whilst retaining their biological function. This thesis focuses on extending CCC to the separation of proteins, using a model ATPS of PEG-1000 and potassium dihydrogen phosphate to separate a mixture of lysozyme and myoglobin. Initial studies were on the behaviour of this phase system in aJ- type CCC centrifuge fitted with a multilayer column; the variable parameters examined were centrifuge rotational speed, mobile phase flow rate and direction, and type of mobile phase. A set of optimum conditions were identified that gave good retention and stability of the phases in the column. These conditions were applied to separate a mixture of the proteins lysozyme and myoglobin in the same centrifuge. However, the proteins did not elute as predicted from their equilibrium distribution ratios. It appears that the wave - like mixing and settling behaviour of the phases in the centrifuge was insufficient for the proteins to achieve equilibrium partitioning. A centrifugal partition chromatography (CPC) centrifuge was introduced to the study. This provided full protein separation, credited to the cascade phase mixing created by this design of centrifuge. The experimental parameters were used in an experiment on a pilot - scale CPC instrument. The CPC study was extended to the isolation of a target protein (phosphomannose isomerase) from a fermentation supernatant. CPC gave partial purification of the protein with retention of enzyme activity. This thesis demonstrates the importance of phase mixing in CCC, which has led to a new column design by BIB with the potential of industrial - scale protein purifications

    Advanced modelling and visualisation of liquid-liquid separations of complex sample components, with variable phase distribution and mode of operation

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    This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research is about liquid-liquid chromatography modelling. While the main focus was on liquid-liquid chromatography, where the stationary and mobile phases are both liquid, theory of different types of chromatography, including the currently most used techniques, were considered as well. The main goal of this research was to develop a versatile liquid-liquid separation model, able to model all potential operating scenarios and modes of operation. A second goal was to create effective and usable interfaces to such a model, implying primarily information visualisation, and secondarily educative visualisation. The first model developed was a model based on Counter-Current Distribution. Next a new more elemental model was developed, the probabilistic model, which better models continuous liquid-liquid chromatography techniques. Finally, a more traditional model was developed using transport theory. These models were used and compared to experimental data taken from literature. The models were demonstrated to model all main liquid-liquid chromatography techniques, incorporated the different modes of operation, and were able to accurately model many sample components and complex sample injections. A model interface was developed, permitting functional and effective model configuration, exploration and analysis using visualisation and interactivity. Different versions of the interface were then evaluated using questionnaires, group interviews and Insight Evaluation. The visualisation and interactivity enhancements have proven to contribute understanding and insight of the underlying chromatography process. This also proved the value of the Insight Evaluation method, providing valuable qualitative evaluation results desired for this model interface evaluation. A prototype of a new graphical user interface developed, and showed great potential for combining model parameter input and exploring the liquid-liquid chromatography processes. Additionally, a new visualisation method was developed that can accurately visualise different modes of operation. This was used to create animations, which were also evaluated. The results of this evaluation show the new visualisation helps understanding of the liquid-liquid chromatography process amongst CCC novices. The model software will be a valuable tool for industry for predicting, evaluating and validating experimental separations and production processes. While effective models already existed, the use of interactive visualisation permits users to explore the relationship between parameters and performances in a simpler yet more powerful way. It will also be a valuable tool for academia for teaching & training, both staff and students, on how to use the technology. Prior to this work no such tool existed or existing tools were limited in their accessibility and educational value.This study was supported by Brunel University and the Royal Academy of Engineering

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

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