1,720,967 research outputs found
Movie 6 and 7
No full text
Movie 6 and 7: FIB-SEM visualizations of the basolateral compartment of type II VHCs with corresponding 3D segmentations.
Movies scanning through the FIB-SEM z-stacks of P15 (Movie 6) and 8-month-old (Movie 7) type II VHCs. The corresponding 3D models depict VHC contours (transparent gray), part of the nuclei (dark gray), innervating nerve fibers (blue), mainly single attached ribbon synapses (red) and their corresponding SVs (yellow). Additionally, some afferent fibers possess multiple ribbons per bouton (Movie 6).</p
Movie 4 and 5
No full text
Movie 4 and 5: FIB-SEM visualizations of type I VHCs with 3D segmentation of single ribbons and ribbon clusters.
Movies scanning through the representative FIB-SEM z-stacks of P15 (Movie 4) and 8-month-old (Movie 5) type I VHCs, showing 3D reconstruction of the VHC contours (transparent gray), part of the nuclei (dark gray), synaptic ribbons (red) and their corresponding SVs (yellow). Movie 4 displays two neighboring P15 type I VHCs likely from the striola that are enclosed by one complex calyx. </p
Movie 1
No full textMovie 1-3: Electron tomography with 3D segmentation of ribbon cluster and single attached ribbons.
Tomograms and their corresponding 3D models of mature (3 months) type I/II VHCs depicting several disc-shaped floating ribbons in type I VHCs and typical single attached ribbons in type II VHCs. The different SV pools, membrane-proximal (MP)-SVs and ribbon-associated (RA)-SVs, are defined as displayed in Fig. S1A.
Red: ribbon, magenta: presynaptic density, dark blue: postsynaptic density, light blue: HC membrane, yellow: SVs, orange: MP-SVs, green: RA-SVs, brown: SV not associated with the ribbon but part of the cluster “cloud”. Scale bars: 200 nm. </p
Movie 10 and 11
No full textMovie 10 and 11: 3D visualization of mitochondria from FIB-SEM z-stacks of P15 and 8-month-old type I and type II VHCs.
Movies show 3D reconstructions of VHC contours (transparent gray), part of the nuclei (dark gray) and mitochondria (randomly colored). </p
Movie 9
No full text
Movie 9: Filamentous network at the nucleus level can be traced in a partial FIB-SEM z-stack of an 8-month-old type I VHC.
Movie displays a large microfilament network (highlighted with arrowheads) proximal to a ribbon cluster (highlighted by a red circle).</p
Movie 3
No full text
Movie 1-3: Electron tomography with 3D segmentation of ribbon cluster and single attached ribbons.
Tomograms and their corresponding 3D models of mature (3 months) type I/II VHCs depicting several disc-shaped floating ribbons in type I VHCs and typical single attached ribbons in type II VHCs. The different SV pools, membrane-proximal (MP)-SVs and ribbon-associated (RA)-SVs, are defined as displayed in Fig. S1A.
Red: ribbon, magenta: presynaptic density, dark blue: postsynaptic density, light blue: HC membrane, yellow: SVs, orange: MP-SVs, green: RA-SVs, brown: SV not associated with the ribbon but part of the cluster “cloud”. Scale bars: 200 nm. </p
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Movie 8
No full textMovie 8: Ribbon cluster formation of a type I VHC.
Overview of a partial FIB-SEM z-stack showing a typical ribbon cluster formation at higher magnification of an 8-month-old type I VHC. Several floating ribbons can be observed in close proximity to the VHC membrane exhibiting no membrane attachment. </p
Movie 2
No full text
Movie 1-3: Electron tomography with 3D segmentation of ribbon cluster and single attached ribbons.
Tomograms and their corresponding 3D models of mature (3 months) type I/II VHCs depicting several disc-shaped floating ribbons in type I VHCs and typical single attached ribbons in type II VHCs. The different SV pools, membrane-proximal (MP)-SVs and ribbon-associated (RA)-SVs, are defined as displayed in Fig. S1A.
Red: ribbon, magenta: presynaptic density, dark blue: postsynaptic density, light blue: HC membrane, yellow: SVs, orange: MP-SVs, green: RA-SVs, brown: SV not associated with the ribbon but part of the cluster “cloud”. Scale bars: 200 nm. </p
- …
