86,813 research outputs found
Esercizi di ANALISI DIFFERENZIALE e CALCOLO INTEGRALE
No full textEsercizi di ANALISI DIFFERENZIALE e CALCOLO INTEGRALE per gli studenti di Economia e Commerci
Enhancement of structural rearrangement in glassy systems under shear flow
No full textWe extend the analysis of the mean field schematic model
recently introduced (see Corberi F., Nicodemi M., Piccioni M. and Coniglio A.
Phys. Rev. Lett., 83 (1999) 5054)
for the description of
glass forming liquids to the case of a supercooled fluid
subjected to a shear flow
of rate γ.
After quenching the system to a low temperature T,
a slow glassy regime is observed before
stationarity is achieved at the characteristic
time \tau _\ab{g}.
\tau _\ab{g} is of the order of the
usual equilibration time without shear \tau _\ab{g}^0
for weak shear,
\gamma \tau _\ab{g} ^0<1. For larger
shear, \gamma \tau _\ab{g} ^0>1,
local rearrangement of dense regions is instead enhanced
by the flow, and \tau_\ab{g} \simeq 1/(T\gamma)
Empirical antimicrobial therapy and qtc interval prolongation in emergency medicine
No full textBackground: QTc prolongation is a common though dangerous clinical condition, associated with increased risk of life-threatening arrhythmia torsades de pointes. The goal of this short communication is to evaluate the principal causes of risk of QTc prolongation that are observed in an emergency department and discuss the differences between drug- and non-drug-associated factors.
Methods: The retrospective analysis is carried out on 130 patients that presented a QTc prolongation (>480 ms for man and >470 for female, respectively), admitted to the emergency department of a single Italian hospital. Patients with pace-maker (22) were excluded from this study. For each patients a minimum of 3 ECGs (12 leads) were recorded. Attention is paid on electrolytes disturbances and to the pharmacotherapy, with a particular emphasis to the use of antibiotics.
Results: Mean age of the patients was 79.6 years (SD=11.3) and female and man were almost equally present (46.6 % F, 53.7 % M). The average QTc value is 492.2 ms (493.3 ms F, 492.8 M). The patients were divided in those with electrolytes disturbances (24.0 %), antimicrobial therapy (35.2%), both antimicrobial therapy and electrolytes disturbances (24.1 %), and other causes of QTc prolongation (16.7 %).
Conclusions: This analysis shows the relevance of the empirical therapy established at the admission, in particular for infective diseases, as an important risk factor for the prolongation of QTc. Other factors that can increase the risk are electrolytes alterations, advanced age, cardiovascular diseases, drug-drug interaction
Critical-comparative analysis of the historical theatres in Emilia damaged by the 2012 Earthquake.
No full textThis contribution aims to highlight the results of the critical-comparative analysis applied to the sample of theatres of the Emilia crater damaged by the 2012 earthquake. This aspect is a substantial part of the methodological framework of the PhD research conducted within the 34th cycle of the IDAUP program - International Doctorate in Architecture and Urban Planning - of the University of Ferrara and funded by the Emilia-Romagna Region program "Three-year high skills plan for research, technology transfer and entrepreneurship" according to Legislative Assembly and Representative Deliberation N. 38, 20/10/2015, ERDF ESF 2014/2020 thematic objective 10. Through the integrated documentation of the Historical Theatres of Emilia-Romagna affected by the 2012 earthquake, the research aims to elaborate on one hand a meta-form- expeditious protocol- for the survey of seismic damage for the specific architectural typology, intended as an implementation of the current MiC procedures, on the other hand, the development of the integrated protocol of seismic damage survey, specific for the analysed architectural typology. The integrated protocol starting from the systematization of data and metadata archived by the Agency for the reconstruction of the Emilia-Romagna Region proposes the digital implementation of the same within the H-BIM platform developed under the INCEPTION project, funded by the European Commission and coordinated by the Department of Architecture of the University of Ferrara, to ensure the mitigation and management of seismic risk in both emergency and routine programmatic maintenance
Corrigendum: Plasticity Induced in the Human Spinal Cord by Focal Muscle Vibration
No full textCorrigendum: Plasticity Induced in the Human Spinal Cord by Focal Muscle Vibration by Rocchi, L., Suppa, A., Leodori, G., Celletti, C., Camerota, F., Rothwell, J., et al. (2018). Front. Neurol. 9:935. doi: 10.3389/fneur.2018.00935
Transcranial magnetic stimulation as a tool to induce and explore plasticity in humans
No full textActivity-dependent synaptic plasticity is the main theoretical framework to explain mechanisms of learning and memory. Synaptic plasticity can be explored experimentally in animals through various standardized protocols for eliciting long-term potentiation and long-term depression in hippocampal and cortical slices. In humans, several non-invasive protocols of repetitive transcranial magnetic stimulation and transcranial direct current stimulation have been designed and applied to probe synaptic plasticity in the primary motor cortex, as reflected by long-term changes in motor evoked potential amplitudes. These protocols mimic those normally used in animal studies for assessing long-term potentiation and long-term depression. In this chapter, we first discuss the physiologic basis of theta-burst stimulation, paired associative stimulation, and transcranial direct current stimulation. We describe the current biophysical and theoretical models underlying the molecular mechanisms of synaptic plasticity and metaplasticity, defined as activity-dependent changes in neural functions that modulate subsequent synaptic plasticity such as long-term potentiation (LTP) and long-term depression (LTD), in the human motor cortex including calcium-dependent plasticity, spike-timing-dependent plasticity, the role of N-methyl-D-aspartate-related transmission and gamma-aminobutyric-acid interneuronal activity. We also review the putative microcircuits responsible for synaptic plasticity in the human motor cortex. We critically readdress the issue of variability in studies investigating synaptic plasticity and propose available solutions. Finally, we speculate about the utility of future studies with more advanced experimental approaches
A Course of Architectural Documentation Through the Clouds. The Challenge of Teaching Survey Techniques During the Pandemic Emergency
No full textIs it possible to teach architectural documentation techniques without being in contact with the artefact? This was the challenge when, in February 2020, at the beginning of an Architectural Survey and Representation Techniques course, the pandemic forced lecturers and students to work from their own homes.
The course was structured to provide the students with an effective methodology able to make the scholars aware of architectural documentation techniques through a learning by doing process using as subject of investigation their own houses and online materials.
After a first phase of identification of possible mitigation actions to fill the gap of on-line teaching in a discipline that needs a strong contact with the architectural space, the education staff conceived a teaching methodology based on a digital architectural space, a point cloud of Palazzo del Merenda, an historical building located in Forlì city center, in Italy.
In this way by the exploration of the point cloud the students became familiar with a more complex architecture, simulating a direct survey and then describing spaces, decoration features, and developing spatial analyses.
The analysis of the point cloud, using the open-source software CloudCompare, allowed the students to investigate and examine the Palazzo del Merenda’s spatial and formal survey’s complexity. The segmentation of the point cloud and the subsequent reconstitution in AutoCAD allowed the students to know, verify and control the logical process from the acquisition to the elaboration of 3d data, understanding the spatial/architectural relationships and achieving the final documentation goal by technical drawings
Classification and systematisation of digital documentation
No full textDocumentation and digital representation represented the crucial nodes of the doctoral thesis “Optimisation of survey pro- cedures and application of integrated digital tools for seismic risk mitigation of cultural heritage: The damaged theatres of Emil- ia-Romagna” developed within the XXXIV cycle of the IDAUP International Doctorate, University of Ferrara. These two aspects underlie and feed the procedural workflow developed in the research iter, whose goal is to provide an application methododology for the collection, acquisition, and hierarchisation of data and information related to seismic damage for the complex typology of historic theatres. The primary purpose of the integrated workflow of damage survey procedures is to provide multi-criteria, multi-level systematic documentation that ensures the optimised mitigation, management, and monitoring of seismic damage by systematising multiple layers of information (MIC damage forms, archival historical information, iconographic and photographic data, and morphometric digital 3D models) within a single HBIM information “container”. The operation of systematisation of the information and data collected represents a knowledge step to discretising the geometric components and quantitative and qualitative parameters necessary and valuable for the information populating the parametric model so that it can be an interpretable, interoperable documentation tool that can be used by all the actors operating in the post-emergency and reconstruction phase. This contribution illustrates, in particular, the integrated application methodological workflow of the damage survey on two case studies of the doctoral research: the Borgatti Theater and the Theater of Novi di Modena
- …
