1,721,570 research outputs found
suppl_2_table_goodness_of_fit – Supplemental material for Nursing Faculties’ Knowledge of and Attitudes Toward Research Ethics According to Demographic Characteristics and Institutional Environment in Korea
No full textSupplemental material, suppl_2_table_goodness_of_fit for Nursing Faculties’ Knowledge of and Attitudes Toward Research Ethics According to Demographic Characteristics and Institutional Environment in Korea by Sukhee Ahn, Geum Hee Jeong, Hye Sook Shin, Jeung-Im Kim, Yunmi Kim, Ju-Eun Song, Sun-Hee Kim, Ju Hee Kim, Yun Jung Lee, Young A. Song, Eun Hee Lee and Myoung-Hee Kim in SAGE Open</p
suppl__enquette – Supplemental material for Nursing Faculties’ Knowledge of and Attitudes Toward Research Ethics According to Demographic Characteristics and Institutional Environment in Korea
No full textSupplemental material, suppl__enquette for Nursing Faculties’ Knowledge of and Attitudes Toward Research Ethics According to Demographic Characteristics and Institutional Environment in Korea by Sukhee Ahn, Geum Hee Jeong, Hye Sook Shin, Jeung-Im Kim, Yunmi Kim, Ju-Eun Song, Sun-Hee Kim, Ju Hee Kim, Yun Jung Lee, Young A. Song, Eun Hee Lee and Myoung-Hee Kim in SAGE Open</p
dataset_Coding_2 – Supplemental material for Nursing Faculties’ Knowledge of and Attitudes Toward Research Ethics According to Demographic Characteristics and Institutional Environment in Korea
No full textSupplemental material, dataset_Coding_2 for Nursing Faculties’ Knowledge of and Attitudes Toward Research Ethics According to Demographic Characteristics and Institutional Environment in Korea by Sukhee Ahn, Geum Hee Jeong, Hye Sook Shin, Jeung-Im Kim, Yunmi Kim, Ju-Eun Song, Sun-Hee Kim, Ju Hee Kim, Yun Jung Lee, Young A. Song, Eun Hee Lee and Myoung-Hee Kim in SAGE Open</p
Potentiation of antidepressant effect of imipramine by repeated treatment with ethaverine.
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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Abstract 3967: High microsomal PGE2synthase-1 levels associate with low CD8 T cells and poorer melanoma patient survival
No full textAbstract
COX-2 and its product PGE2 are reported to enhance carcinogenesis and tumor progression and to support immunosuppression, as reported by others in melanoma and other cancers. As most COX-2 inhibitors result in cardiotoxicity, the downstream microsomal PGE2 synthase-1 (mPGES1) is now also an alternative consideration for therapeutic targeting. Our previously published results (Kim, et al., 2016) showed that mPGES1 protein increased with melanoma patient clinical stage and that its intense expression was associated with reduced patient survival. We also reported that mPGES1 inhibition attenuated cell survival and increased apoptosis in human melanoma cells and significantly suppressed tumor growth in melanoma xenografts. This current study was designed to evaluate whether expression of mPGES1 contributes to immune evasion. Tumors in a Stage III melanoma TMA analysis demonstrated that high mPGES1 expression (intensity 3) was significantly associated with low CD8 levels (lower than median CD8 percent value) (r=-0.2722, p=0.0128). Importantly, stage III melanoma patients with this high mPGES1 and low CD8 signature had significantly increased risk of death as determined by Kaplan-Meier method and Univariate Cox proportional hazards regression models, and compared with patients with low mPGES1/low CD8 and low mPGES1/high CD8. Furthermore, the differential levels of several chemokines including CXCL1 and CXCL2 to regulate T cell migration were correlated the mPGES1 expression in the TCGA melanoma data set. Collectively, our study continues to resolve the potential role of mPGES1 in regulation of immune evasion and is designed as a preclinical approach to develop a rational therapeutic strategy targeting PGE2-driven inflammatory mediators as useful adjuvants for immune-based therapy.
Citation Format: Sun-Hee Kim, Jason Roszik, Weiyi Peng, Suhendan Ekmekcioglu, Elizabeth A. Grimm. High microsomal PGE2synthase-1 levels associate with low CD8 T cells and poorer melanoma patient survival [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3967. doi:10.1158/1538-7445.AM2017-3967</jats:p
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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