328 research outputs found
Identification and characterization of a novel Shigella flexneri serotype Yv in China.
Shigella flexneri is the major cause of bacterial shigellosis in developing countries. S. flexneri is divided into at least 19 serotypes, the majority of which are modifications of the same basic O-antigen by glucosylation and/or O-acetylation of its sugar residues by phage encoded serotype-converting genes. Recently, a plasmid encoded phosphoethanolamine (PEtN) modification of the O-antigen has been reported, which is responsible for the presence of the MASF IV-1 determinant and results in conversion of traditional serotypes X, 4a and Y to novel serotypes Xv, 4av and Yv, respectively. In this study, we characterized 19 serotype Yv strains isolated in China. A variant of the O-antigen phosphoethanolamine transferase gene opt (formerly called lpt-O) carried by a pSFxv_2-like plasmid was found in serotype Yv strains, which specifies the phosphorylation pattern on the O-antigen of this serotype. For the majority of the O-antigen units, the PEtN modification occurs on Rha(III), while for a minority, modifications occur on both Rha(II) and Rha(III). Serotype-specific gene detection and PFGE analysis suggested that these serotype Yv isolates were originated from serotypes Y, Xv and 2a by acquisition of an opt-carrying plasmid and/or inactivation of serotype-specific gene gtrII or gtrX. These data, combined with those of serotypes Xv and 4av reported earlier, demonstrate that the plasmid-encoded PEtN modification is an important serotype conversion mechanism in S. flexneri, in addition to glucosylation and O-acetylation
Assessment of Strengths in Criminal Justice System-Impacted Youth: A Retrospective Validation Study of the SAPROF-YV
This is an online first open access publication.The Structured Assessment of Protective Factors for Violence Risk-Youth Version (SAPROF-YV; de Vries Robbé et al., 2015) was designed specifically to assess strengths as a complement to risk assessment tools. We retrospectively examined its reliability and validity in 305 Canadian community-sentenced youth, both in the overall sample and in male and female, and Black and White, subgroups. In all groups, the total score had strong internal consistency, inter-rater reliability, and convergent validity, and significantly predicted general recidivism at 3-year fixed follow-up. The SAPROF-YV showed incremental validity over the YLS/CMI only in Black youth. In the total sample, a moderation effect was identified whereby strengths were protective at lower levels of risk but not for moderate or high risk youth. The SAPROF-YV shows promising reliability and validity; however, more research is needed before clear guidance can be provided regarding the use of this measure in clinical practice.Funding for this research was supported in part by a SSHRC Doctoral Scholarship to the first author
Schematic diagram of the putative origins of the serotype Yv isolates.
<p>The serotypes, serotype-converting phages and the plasmid gene involved are indicated in ellipses. The O-antigen structures of different serotypes are shown below the ellipses. Sugar residues and modifications are displayed in symbols as shown. The order of occurrence of the gene inactivation and acquisition of the <i>opt</i>-carrying plasmid is unknown and alternative orders are thus depicted. Putative intermediate serotypes between 2a and Yv are indicated in dashed ellipses.</p
California recession and recovery
California ; Economic conditions - United States ; Recessions
A review of solar collectors and thermal energy storage in solar thermal applications
Thermal applications are drawing increasing attention in the solar energy research field, due to their high performance in energy storage density and energy conversion efficiency. In these applications, solar collectors and thermal energy storage systems are the two core components. This paper focuses on the latest developments and advances in solar thermal applications, providing a review of solar collectors and thermal energy storage systems. Various types of solar collectors are reviewed and discussed, including both non-concentrating collectors (low temperature applications) and concentrating collectors (high temperature applications). These are studied in terms of optical optimisation, heat loss reduction, heat recuperation enhancement and different sun-tracking mechanisms. Various types of thermal energy storage systems are also reviewed and discussed, including sensible heat storage, latent heat storage, chemical storage and cascaded storage. They are studied in terms of design criteria, material selection and different heat transfer enhancement technologies. Last but not least, existing and future solar power stations are overviewed
Soutenance de thèse de Ting Sun "La place du transport semi-collectif dans les mutations des systèmes de mobilité urbaine en Chine : le cas de Shanghai" - ENPC (Champs-sur-Marne) - 5 décembre 2016
Soutenance de thèse de Ting Sun "La place du transport semi-collectif dans les mutations des systèmes de mobilité urbaine en Chine : le cas de Shanghai" Lieu : ENPC, 6-8 avenue Blaise-Pascal, Cité Descartes (Champs-sur-Marne) Date : 5 décembre 2016 Membres du jury : Marie-Helene MASSOT, Professeure à l'Université Paris Est-Créteil, présidente du jury. Michel SAVY, Professeur émérite à l’Université Paris Est, directeur de la thèse. Jian ZHUO, Professeur à l’Université de Tongji, rapporteur. Yv..
The presence of <i>opt-</i>carrying plasmid in serotype Yv isolates, and genomic comparison with pSFxv_2 of strain 2002017 (accession No. CP001385).
<p>A, plasmid profiles of the 19 serotype Yv isolates. Plasmid DNA was separated by electrophoresis with a Chef Mapper system (Bio-Rad) on a 1% SeaKem Gold agarose gel and visualized by EB staining. Red arrow indicates the position of <i>opt-</i>carrying plasmid. Plasmids isolated from strain 2002017 were used as control. Lambda DNA cleaved with <i>Hind</i>III (TaKaRa, Japan) was used as molecular mass markers. Southern hybridization detection of the <i>opt</i> gene in serotype Yv isolates is shown beneath the gel picture. B, genomic comparison of pSFyv_2 of strain HN006 and pSFxv_2 of 2002017. ORFs were shown as thick arrows, and coding regions were marked according to the genome annotations. The base changes were indicated using blue lines.</p
Soutenance de thèse de Ting Sun "La place du transport semi-collectif dans les mutations des systèmes de mobilité urbaine en Chine : le cas de Shanghai" - ENPC (Champs-sur-Marne) - 5 décembre 2016
Soutenance de thèse de Ting Sun "La place du transport semi-collectif dans les mutations des systèmes de mobilité urbaine en Chine : le cas de Shanghai" Lieu : ENPC, 6-8 avenue Blaise-Pascal, Cité Descartes (Champs-sur-Marne) Date : 5 décembre 2016 Membres du jury : Marie-Helene MASSOT, Professeure à l'Université Paris Est-Créteil, présidente du jury. Michel SAVY, Professeur émérite à l’Université Paris Est, directeur de la thèse. Jian ZHUO, Professeur à l’Université de Tongji, rapporteur. Yv..
'Happy as in Queer' - The Affective Paradoxes of Queer Families
The restrictive legal and political regulations of queer families in Switzerland provide the basis of this paper. Within this context, Lesbians, Gays, Bisexuals, Transgender and Queers (LGBTQ's) aim to have their families recognized less through shared genetic substances and more through the public mediation of affects such as happiness. Consequently, the author attends to the affective politics of imagining and living families by LGBTQ's. The author draws upon ethnographic data to explore how happiness structures modes of relatedness in terms of family. With an affect theory stance, the paper turns to two case studies which allow to apply and eventually extend Sara Ahmed's concept of the family as a 'promise of happiness' (Ahmed 2010a). By means of the case studies, the author elaborates on how queer families are linked to a normalized, heteronormative figure of 'the family,' as well as to dissident modes of relatedness. An affect theory-based analysis leads the author finally to challenge the contrasting juxtaposition of normalized and dissident politics of LGBTQ's by concluding that such politics of affects blur the lines between assimilationist versus resisting politics and have to be understood as paradoxical
On the Stability of Nonlinear Time-Varying Systems
Concerning the absolute stability of a nonlinear time-varying feedback system, an important correction to the results of the author [1] is presented
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