1,948,289 research outputs found
Dr. Lin Sun, CAU, March 2013
No full textThis video is a conversation with Dr. Lin Sun. Dr. Sun talks about an exhibit at the Woodruff Library titled "At The Boundary." Jordan Moore, AUC Woodruff Library, is the interviewer
Assessment of Self-Archiving in Institutional Repositories: Depositorship and Full-Text Availability
No full textThis research evaluates the success of open access self-archiving in several well-known institutional repositories. Two assessment factors have been applied to examine the current practice of self-archiving: depositorship and the availability of full text. This research discovers that the rate of author self-archiving is low and that the majority of documents have been deposited by a librarian or administrative staff. Similarly, the rate of full-text availability is relatively low, except for Australian repositories. By identifying different practices of self-archiving, repository managers can create new strategies for the operation of their repositories and the development of archiving policies
A Metadata Manager's Role in Collaborative Projects: The Rutgers University Libraries Experience
No full textPurpose – This article discusses the roles and responsibilities of a metadata manager in collaborative digital projects.
Methodology – It describes the general requirements for metadata management, and introduces some scenarios in the practices of digital projects by the Rutgers University Libraries to support the generalized definition. A workflow of metadata management is illustrated.
Practical implications – With an explicit definition of the roles and responsibilities of the metadata manager, many other digital libraries that need to develop a new or optimize the existing workflow may find the Rutgers experience useful as reference.
Originality – Very few articles have explored this topic although the functions of metadata in the development of digital projects have been talked extensively.Peer reviewe
Batch Loading in Metadata Creation: A Case Study the Rutgers University Libraries Experience
No full textPurpose – The purpose of this article is to describe a workflow of automated batch loading metadata from existing text to a database.
Methodology/Approach – It introduces a case for the experience of metadata creation at Rutgers University Libraries in a collaborative digital project with the Hoboken Public Library in New Jersey.
Findings – It is found that a well-designed workflow is crucial to the success of metadata batch loading. It is also found that the metadata manager needs to collaborate with people of different roles and work carefully with data reorganization and transferring.
Practical Implications – Metadata creation and management is an integrated component of any digital project. Our experience in metadata batch loading has practical significance that may be incorporated into the practice of other metadata projects. The workflow introduced in this article will provide valuable example for librarians and information professionals to consider or redesign their own digital efforts.
Originality – Based on our real exercise, this workflow has been proven to be unique and useful. It was, after the writing of this article, applied to a new collaborative digital project and once again fulfilled the requirements for another batch transferring process.Peer reviewe
Applying the NISO Metasearch Initiative Scheme to Enhance E-Resources Management at Rutgers University Library
No full textThis paper discusses problems in the management of library e-resources and attempts to identify potential solutions to the problems. By describing an e-resources enhancement project taken by Rutgers University Libraries, this paper points to the importance of providing contextually-rich metadata and reorganizing the accessibility of e-resources on a library’s website. It introduces how this Rutgers project adopted the National Information Standards Organization Metasearch Initiative to support the identification of appropriate e-collections for metaseaching. The outcomes of the project have facilitated a dynamic display of relevant e-resources to library users as an effective way of automatic access to library e-collections.Peer reviewe
Factors to Assess Self-Archiving in Institutional Repositories
No full textThis paper proposes a group of factors that may be used to assess the success of open access self-archiving. It concentrates on self-archiving in institutional repositories. The authors emphasize the importance of examining content materials, particularly the availability of full text versus abstracts and the deposits archived by authors versus by others.Peer reviewe
Extension of the sun-synchronous Orbit
No full textThrough careful consideration of the orbit perturbation force due to the oblate nature of the primary body a secular variation of the ascending node angle of a near-polar orbit can be induced without expulsion of propellant. Resultantly, the orbit perturbations can be used to maintain the orbit plane in, for example, a near-perpendicular (or at any other angle) alignment to the Sun-line throughout the full year of the primary body; such orbits are normally termed Sun-synchronous orbits [1, 2]. Sun-synchronous orbits about the Earth are typically near-circular Low-Earth Orbits (LEOs), with an altitude of less than 1500 km. It is normal to design a LEO such that the orbit period is synchronised with the rotation of the Earth‟s surface over a given period, such that a repeating ground-track is established. A repeating ground-track, together with the near-constant illumination conditions of the ground-track when observed from a Sun-synchronous orbit, enables repeat observations of a target over an extended period under similar illumination conditions [1, 2]. For this reason, Sun-synchronous orbits are extensively used by Earth Observation (EO) platforms, including currently the Environmental Satellite (ENVISAT), the second European Remote Sensing satellite (ERS-2) and many more. By definition, a given Sun-synchronous orbit is a finite resource similar to a geostationary orbit. A typical characterising parameter of a Sun-synchronous orbit is the Mean Local Solar Time (MLST) at descending node, with a value of 1030 hours typical. Note that ERS-1 and ERS-2 used a MLST at descending node of 1030 hours ± 5 minutes, while ENVISAT uses a 1000 hours ± 5 minutes MLST at descending node [3]. Following selection of the MLST at descending node and for a given desired repeat ground-track, the orbit period and hence the semi-major axis are fixed, thereafter assuming a circular orbit is desired it is found that only a single orbit inclination will enable a Sun-synchronous orbit [2]. As such, only a few spacecraft can populate a given repeat ground-track Sun-synchronous orbit without compromise, for example on the MLST at descending node. Indeed a notable feature of on-going studies by the ENVISAT Post launch Support Office is the desire to ensure sufficient propellant remains at end-of-mission for re-orbiting to a graveyard orbit to ensure the orbital slot is available for future missions [4]. An extension to the Sun-synchronous orbit is considered using an undefined, non-orientation constrained, low-thrust propulsion system. Initially the low-thrust propulsion system will be considered for the free selection of orbit inclination and altitude while maintaining the Sun-synchronous condition. Subsequently the maintenance of a given Sun-synchronous repeat-ground track will be considered, using the low-thrust propulsion system to enable the free selection of orbit altitude. An analytical expression will be developed to describe these extensions prior to then validating the analytical expressions within a numerical simulation of a spacecraft orbit. Finally, an analysis will be presented on transfer and injection trajectories to these orbits
Chinese media
No full textFrom an area of specialist research a decade ago China’s media has become now an important element of research and teaching worldwide, not only in specific Chinese cultural studies courses at the university level but increasingly in post-graduate research and in the domain of business consultancy.\ud
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Edited by Michael Keane and Wanning Sun, leading experts in the field, this new title is a ‘mini library’ of the foundational and the very best cutting-edge scholarship on Chinese medi
Kim, Sun-A
No full text학위논문(석사)--아주대학교 일반대학원 :분자과학기술학과,2011. 2인체의 뼈는 분해와 생성을 반복하면서 항상성이 유지된다. 뼈의 생성이 증가되면 골의 석회화가 이루어지는 반면, 뼈의 손실이 증가되면 골다공증, 관절염 등의 다양한 질병을 유발된다. 이러한 뼈의 항상성 조절에 있어 뼈의 분해를 조절하는 방법으로 osteoclasts 의 분화나 활성 억제에 대한 연구가 진행 중이다. Osteoclast는 골수 유래의 hematopoietic monocyte / macrophage에서 분화되는 세포로써 cell fusion을 통해 다핵세포가 만들어지며 TRAP발현이 증가되는 특징을 갖는다. 주로 RANKL나 M-CSF에서 분화된다고 알려지지만 최근에 LPS와 같은 염증유발물질에 의해서도 osteoclastogenesis가 유발된다고 보고됐다. 최근 연구에 따르면 지방의 섭취가 뼈의 turnover를 줄이거나 fatty acid가 osteoclast 형성을 억제한다는 내용의 연구들이 보고됐다. Fatty acid는 carbon chain의 길이와 functional group에 따라 그 종류가 다양하다. 이러한 fatty acid는 주로 에너지원으로 사용될 뿐만 아니라, 다양한 생체내에 process를 조절한다. 따라서 본 연구에서는 면역보강제로 사용되는 medium chain fatty acid중 하나인 capric acid를 RAW 264.7 cell에 처리하여 LPS에 의해 유도되는 osteoclastogenesis에 대한 효과와 그 기전을 알아보고자 하였고, TRAP assay결과 LPS에 의해 증가된 TRAP 활성이 capric acid에 의해 감소됨을 확인하였다. 세포의 분화나 증식에 관여한다고 알려진 STAT3 activation이 capric acid에 의해 억제됐다. 또한 cell fusion을 유도한다고 알려진 iNOS 와 MCP-1발현이 감소됨을 관찰하였다. 따라서, capric acid는 STAT3 활성을 억제시킴으로써 cell fusion을 유발하는 NO나 MCP-1의 생성을 감소시키고 결국 LPS에 의해 유발되는 osteoclastogenesis에 대한 억제효과를 나타내고 있음을 보여준다. 이러한 결과는 뼈 손실과 관련된 다양한 질환의 치료에서 유용성 있는 가능성 있는 하나의 후보물질로서의 가능성을 제시해 주고 있다.INTRODUCTION 1
MATERIALS AND METHODS 4
RESULTS 9
DISCUSSION 21
CONCLUSION 24
REFERENCES 25
국문요약 32MasterOsteoclastogenesis is mainly derived from bone marrow hematopoietic monocytes/macrophages. Substantial increase in the concentration of osteoclastogenesis, leads to bone diseases such as rheumatoid arthritis, osteoporosis and periodotitis. Therefore, regulation of osteoclastogenesis must be tightly regulated in the context of bone homeostasis. Previous studies have shown that fatty acids are related to bone density and reduces bone turnover. We have hypothesized that fatty acids might have a direct effect on bones, and we have extended this approach to assess the effects of fatty acid in osteoclastogenesis. Capric acid is one of the medium chain fatty acids and is an important ingredient of coconut oil and bovine milk. This study demonstrates that capric acid mediated inhibitory effects on osteoclastogenesis in LPS induced RAW 264.7 cells. Additionally, effects of capric acid cause inhibition of STAT3 activation thereby decreasing the production of NO and MCP-1
A grounded theory of female adolescent behaviour in the sun: comfort matters.
No full textThe aim of the research was to generate a grounded theory to explain the behaviour of young women in the sun. The study sought to explore the sun-related experiences of
young women in order to gain new insights into the influences upon them. The study was qualitative by design and utilised grounded theory method as developed by Glaser.
Twenty female participants, aged 14 to 17 years old were included in the study. They formed six groups. Thirteen interviews were carried out with the groups and six one-to one interviews took place with individuals. All interviews were semi-structured and were based upon the participants' experiences of being in the sun. Data was analysed using the
constant comparative method of data analysis, concordant with Glaserian grounded theory method. Five explanatory categories emerged from the data; Fitting In, Being Myself,
Being Physically Comfortable, Slipping Up and a core category of Being Comfortable. One of the issues that emerged was that some young women believed their social
acceptance depended on their appearance and they conformed to this end. The theory, derived from the categories, proposes that when in the sun, young women direct their
activities toward meeting physical and psychosocial comfort needs. Comfort matters to them because it has implications for their wellbeing. This thesis contributes to the literature about the behaviours of young women in the sun.
By increasing understanding of the factors that influence them, it also adds to the body of knowledge related to the primary prevention of skin cancer with teenage girls in the United Kingdom. The outcome of the research and its contribution to knowledge is a grounded theory, which explains the basis of the behaviours of young women in the sun. It appears that no other study has explored the experiences of UK adolescent females specifically, in
a qualitative way and with the intention of producing a theory to explain them
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