28,057 research outputs found
Author Peter FitzSimons speaking at the National Library of Australia, Canberra, 13 November 2012 /
No full textTitle from acquisitions documentation.; Part of the collection: Portraits of author Peter FitzSimons speaking at the National Library of Australia, Canberra, 13 November 2012.; Acquired in digital format; access copy available online.; Mode of access: Online.; Photographed by a staff member of the National Library of Australia
Moral Good, the Beatific Vision, and God’s Kingdom Writings by Germain Grisez and Peter Ryan, S.J.. Edited by Peter J. Weigel
No full textFor close to half a century, the work of Germain Grisez has been highly influential, and his writings continue to receive considerable attention from philosophers and theologians of diverse viewpoints. His co-author for this work is the professor and noted moral theologian Fr. Peter Ryan, S.J., currently the executive director of the Secretariat of Doctrine and Canonical Affairs of the United States Conference of Catholic Bishops (USCCB). These two eminent scholars explore fundamental questions about Christian eschatology, moral theory, the purpose of human life, and the promise of human fulfilment. The authors examine Christian teaching on the final destiny of persons, investigating the meaning of God's kingdom, the hope of the beatific vision, and the centrality of moral goodness and divine grace in one's final end. This work is an ideal source for students, scholars, ministers and lay persons interested in basic questions of Christian theology, the philosophy of religion, ethical theory, and Catholic doctrin
Murder on the mountain: author talk with Peter J. Wosh
No full textAuthor talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.
Mechanisms to synchronize neuronal activity
No full text Temporal aspects of neuronal activity have received increasing attention in recent years. Oscillatory dynamics and the synchronization of neuronal activity are hypothesized to be of functional relevance to information processing in the brain. Here we review theoretical studies of single neurons at different levels of abstraction, with an emphasis on the implications for properties of networks composed of such units. We then discuss the influence of different types of couplings and choices of parameters to the existence of a stable state of synchronous or oscillatory activity. Finally we relate these theoretical studies to the available experimental data, and suggest future lines of research
Peter Muller (Hrsg.) : Sturm und Drang. Weltanschauliche und ästhetische Schriften, 1978
No full textKrebs Roland. Peter Muller (Hrsg.) : Sturm und Drang. Weltanschauliche und ästhetische Schriften, 1978. In: Dix-huitième Siècle, n°12, 1980. Représentations de la vie sexuelle. pp. 495-496
Thesaurus Pauperum PETRI HISPANI PONTIFICIS ROMANI, PHILOSOPHI AC MEDICI doctißimi, de Medendis morbis humani corporis Liber: Experimenta particularia per simplicia Medicamenta ex probatissimis Autoribus, et proprijs obseruationibus collecta, continens. OPERA ET STVDIO GVLIELMI Adolphi Scribonij Marpurgensis in lucem editus, & multis in locis castigatus. (IVSIVRANDVM MEdicum, quod Discipulis suis Hippocrates praescripsit.)
No full textBeiträger: Dorfheilge, Peter; Hanstein, Nikolaus von; Sturm, Kaspar aus Fritzlar; Vulteius, JustusVorlageform des Erscheinungsvermerks: FRANCOF. apud haered.Chr.Egen.|| M.D.LXXVIII.|| (impensis Adami || Loniceri, Ioannis Cnipij || Andronici secundi,|| Doctorum, & || Pauli Stein-|| meyers.||)Titelbl. in Rot- u. Schwarzdr., Druckerm
Peter Muller (Hrsg.) : Sturm und Drang. Weltanschauliche und ästhetische Schriften, 1978
No full textKrebs Roland. Peter Muller (Hrsg.) : Sturm und Drang. Weltanschauliche und ästhetische Schriften, 1978. In: Dix-huitième Siècle, n°12, 1980. Représentations de la vie sexuelle. pp. 495-496
Lunchtime Talk with Author and Attorney Peter Godwin
No full textAuthor and attorney Peter Godwin gave a lunchtime talk about the topics discussed in his book, The Fear, which focuses on the human rights situation in Zimbabwe under the rule of Robert Mugabe
A general unknown screening for drugs and toxic compounds in human serum
No full textScreening for a wide range of drugs and toxic compounds in biological samples is an
important task for forensic and clinical toxicological laboratories. Our object was to
develop a method to detect and identify a wide range of compounds by using HPLCDAD
and LC-MS.
A solid-phase extraction procedure using polymer-based columns was developed for the
HPLC-DAD procedure. The extraction method appeared very universal. Ninteyfour of
100 drugs were extracted with a recovery of more than 50%.
For the LC-MS procedure, the Prospekt solid-phase extraction was chosen for its ability
to be linked to the atmospheric pressure chemical ionisation (APCI) ion source. With this
procedure all of the tested drugs with LC-MS were successfully extracted.
Hundred compounds from a variety of classes were investigated, if they can be identified
and detected at low toxic serum concentration. Limits of detection were determined in
spiked serum samples.
It was found that HPLC-DAD was able to detect 61 out of 100 compounds with our
procedure at low toxic serum concentration. The limit of detection (LOD) for the
majority of the tested drugs (76%) was ≤ 1’000 ng/mL. Drugs and toxic compounds were
detected by comparison of the retention time and UV spectra with references compounds
stored in a library.
The LC-MS instrument was operated in the positive and in the negative mode using datadependent
acquisition. Tandem mass spectrometry (MS-MS) was applied to identify
toxicologically relevant substances in serum. An application program was created in
order to detect automatically the unknown compounds. Drugs and metabolites were
identified on the basis of their relative retention times, pseudo-molecular ions and
fragment ions. A total of more than 400 spectra of more than 350 compounds were
recorded. The corresponding relative retention times were added to the spectra in the
constructed libraries (one for the positive and the other library for the negative mode).
Eightyseven drugs of compounds were identified from serum using on-line solid-phase
extraction with LC-MS-MS. The limit of detection (LOD) for the majority of compounds
(67%) was ≤ 100 ng/mL, ranging from 10 to 4000 ng/mL.
With the presented fully automated data-dependent LC-MS-MS procedure drugs can be
analysed in serum with a high specificity and sensitivity. The LODs were sufficiently low
to detect compounds at low toxic concentrations in serum. The integrated software
drastically reduced the interpretation time. It was demonstrated that with the DDAmediated-
LC-MS-MS screening approach almost all of the drugs detected by the
conventional techniques as well as additional drugs were identified. This technique is
useful for GUS and confirmation analysis in clinical and forensic toxicology. In general,
LOD for compounds are lower with the LC-MS procedure than the HPLC procedure. For
compounds not able to detect with the LC-MS procedure such as analgesics and
barbiturates HPLC-DAD appeared to be the complement method
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