4,874 research outputs found

    Letter from Carl Hayden to Roy W. James and M. J. Hanley

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    Letter from Carl Hayden to Roy James and M. J. Hanley expressing a wish to soon have a definite answer in regards to their insurance claims

    β-diversity of deep-sea holothurians and asteroids along a bathymetric gradient (NE Atlantic)

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    Measuring and understanding patterns of ?-diversity remain major challenges in community ecology. Recently, ?-diversity has been shown to consist of 2 distinct components: (1) spatial turnover and (2) species loss leading to nestedness. Both components structure deep-sea macrofaunal assemblages but vary in importance among taxa and ocean basins and with energy availability. Here, we present the first evidence for turnover and nestedness along a bathymetric gradient in 2 major megafaunal taxa, holothurians and asteroids. Turnover is the dominant component of ?-diversity throughout bathyal and abyssal zones in both taxa, despite major differences in ?-diversity and trophic composition. High spatial turnover suggests a role for evolutionary adaptation to environmental circumstances within depth bands. This pattern differs fundamentally from those in some macrofaunal groups in low-energy environments where abyssal nestedness is high and diversity low, with diversity maintained partly by source-sink dynamics

    Letter from J. E. Gavin (for Senator Hayden) to Roy W. James, Michael Hanley and H. A. Montgomery

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    Letter from J. E. Gavin on behalf of Carl Hayden writing in regards to the insurance claims filed with the National Park

    Regional integration fifty years after the treaty of Rome. The EU, Asia, Africa and the Americas.

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    The European Union has been the pioneer and undisputed leader of regional integration processes. Since its inception in the 1950s, following the Schuman Declaration that set in motion Jean Monnet’s innovative idea to join together European coal and steel industries, Europe has offered a useful model for regional integration. Strengthened by the 1957 Treaty of Rome (exactly half a century ago), this bold entity was later transformed into the European Union by the Maastricht Treaty. Having successfully accomplished its primary goal (“to make war unthinkable and materially impossible”), the EU is currently facing challenges associated with its expansion and the deepening of its pooled sovereignty. On the other hand, the effects of the EU in international relations are of paramount relevance. While the forceful transposition of national and regional structures into other regions is a historical error, the essence of the EU as a model to be adapted by other regions is a viable approach to enhance stability and welfare. In this regard, this volume examines the current challenges of the EU and the perspectives of regional integration in Africa, Asia and Latin America

    [Photograph 2012.201.B1217.0599]

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    Photograph used for a newspaper owned by the Oklahoma Publishing Company. Caption: "The Stuart football family.. . from left, Roy Stuart, U. S. Navy; father R. J. Stuart; and Bobby Jack Stuart, Tulsa football.

    Labor’s Human Rights: A Review of the Nature and Status of Core Labor Rights as Human Rights

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    © Roy J. Adams. All rights reserved. This paper may be freely circulated in electronic or hard copy provided it is not modified in any way, the rights of the author not infringed, and the paper is not quoted or cited without express permission of the author. The editors cannot guarantee a stable URL for any paper posted here, nor will they be responsible for notifying others if the URL is changed or the paper is taken off the site. Electronic copies of this paper may not be posted on any other website without express permission of the author

    DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire

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    The majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire

    Apparatus for Generating and Carbureting Hydrogen.

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    Patent for an apparatus that will improve the cost efficiency of producing gas. Specifically, this invention details a "main tank which produces hydrogen and an auxiliary tank wherein the hydrogen is mixed with crude petroleum oil and thereby given its illuminating and combustible properties" (lines 18-23)

    Genetic analysis of abiotic stress tolerance in crops

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    Abiotic stress tolerance is complex, but as phenotyping technologies improve, components that contribute to abiotic stress tolerance can be quantified with increasing ease. In parallel with these phenomics advances, genetic approaches with more complex genomes are becoming increasingly tractable as genomic information in non-model crops increases and even whole crop genomes can be re-sequenced. Thus, genetic approaches to elucidating the molecular basis to abiotic stress tolerance in crops are becoming more easily achievable.Stuart J. Roy, Elise J. Tucker and Mark Teste

    Reviews

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    The following publications have been reviewed by the mentioned authors;Welsh Crafts by Mary Eirwen Jones, reviewed by Roy NashA Source Book of Picture Making by Henry Pluckrose, reviewed by R. HartApproaches to Drawing by Leo Walmsley, reviewed by John EgglestonMoulded and Slip Cast Pottery and Ceramics by David Cowley, reviewed by Michael PaffardPainting by John Lancaster, reviewed by R. N. MacGregorDesign Resource Sheets by R. N. Billington and J. R. Jeffrey, reviewed by Dick SuttonEnamelling on Metal, Oppi. Intracht, reviewed by J. N. AtkinsProcesses by Jack Bainbridge, reviewed by Michael SayerArtists and People by Su Braden, reviewed by Roy ShawMake Your Own Musical Instrument by Stuart Dalby, reviewed by Eric DecorteDesign in General Education by John Harahan, reviewed by Bernard AylwardPainting Without a Brush by Roy Sparkes, reviewed by John LancasterBuilding Craft Equipment by A. Jay and Carol W. Abrams, reviewed by S. R. BlundellPyrography by Berhand Havez and Jean-Claude Varlet, reviewed by Paul Kin
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