171,526 research outputs found
The meaning of the Kelly–Lochbaum acoustic-tube model
No full textThe scattering equations of the Kelly-Lochbaum segmented tube, including the time-varying extension, by Strube, are originally based on the assumption of uniform spatial segments and stepwise time update of the acoustic impedances. Here, it is shown that the same equations can be derived without these assumptions for a nonuniform time-varying tube from the discretization of space and time derivatives by the bilinear z transform or by centered differences along the rotated coordinates ct+/-x. Moreover, the same equations also hold for a chain of lattice circuits (or equivalents) with appropriate parameters, if time derivatives are discretized by the bilinear z transform. These circuits can also be extended to simulate uniform segments of varying length. (C) 2000 Acoustical Society of America. [S0001-4966(00)04310-1]
The mushroom body output encodes behavioral decision during sensory-motor transformation
No full textArican C, Schmitt FJ, Rössler W, Strube-Bloss M, Nawrot MP. The mushroom body output encodes behavioral decision during sensory-motor transformation. Current Biology. 2023;33(19):4217-4224.e4
August Gottlieb Spangenberg von Vergebung der Sünde
No full textAutopsie nach dem Exemplar der ULB HalleVorlage des Erscheinungsvermerks: Gnadau, Verlegt und zu finden in der Buchhandlung der evangelischen Brüder-Unität bei Christoph Ernst Senf, so wie in den Brüdergemeinden. - [Magdeburg, gedruckt bey I. C. Strube]Ill
Are conical segments useful for vocal-tract simulation? (L)
No full textA time-domain model for nonuniform tubes is considered which is of similar simplicity as the Kelly-Lochbaum model but based on conical segments. Using the bilinear transform or wave digital filters for representing the reflections at the segment boundaries, stability is proved and numerical instabilities can be overcome. The transfer functions are modeled better than with cylindrical segments but about equally well as with half-length cylinders, requiring about the same computational expense. Thus, in most cases there is no real advantage in using cones. (C) 2003 Acoustical Society of America
UV light perception is modulated by the odour element of an olfactory–visual compound in restrained honeybees
No full textBecker MC, Rössler W, Strube-Bloss M. UV light perception is modulated by the odour element of an olfactory–visual compound in restrained honeybees. The Journal of Experimental Biology. 2019;222(10): jeb201483
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
The effect of the hibernation on the larval development of Troglostrongylus brevior in the land snail Cornu aspersum
No full textTroglostrongylus brevior, a lungworm affecting wild felids, has been increasingly reported in domestic cats from Europe. Troglostrongylosis is a relevant disease that may result in a potentially life-threatening bronchopneumonia, especially in kittens. The life cycle of T. brevior is indirect with terrestrial gastropods acting as intermediate host. The widely distributed spread land snail Cornu aspersum (former Helix aspersa) is competent for T. brevior development and may transmit the nematode in natural conditions. The present study evaluated the larval development of T. brevior in C. aspersum at two different environmental temperature conditions, with a focus on the effect of hibernation. One hundred and seventy snails were infected with 500 first stage larvae (L1) of T. brevior and kept in vivaria at 25 ± 2 °C. Fifteen days post infection (p.i.), 20 specimens were digested to evaluate the overall larval developmental rate from L1 to L3 (2.5 % on days 15 p.i.) and then the snails were divided in two groups, i.e. G1 kept at 25 ± 2 °C and G2 that were hibernated at 4 ± 2 °C. The developmental rate of T. brevior was evaluated in these groups on 30 and 60 days p.i. by snail digestion at each time-point. An additional batch of 40 snails (G2-1) was hibernated on D15 and digested on D60. Larvae recovered were morphologically and morphometrically examined. The infective third larval stage (L3) was detected in the muscular foot of C. aspersum at different rates depending on the environmental temperature. In particular, T. brevior showed a higher developmental rate in hibernated snails (G2: 6.9 % and 14.1 % on days 30 and 60 p.i; G2-1: 4%; G2 + G2-1 overall mean percentage: 9%) compared to non-hibernated snails (G1: 4% and 5.2 % on days 30 and 60 p.i.), indicating that lower temperatures may positively influence the developmental in C. aspersum. These data are suggestive for a seasonal pattern of T. brevior infections under field conditions, with snails containing higher parasitic burdens after their natural hibernation occurring in winter. Studies on the larval development of T. brevior in other mollusc species in field surveys evaluating differences in developmental rates and transmission patterns in different seasons are warranted
SIM - simultaneous inverse filtering and matching of a glottal flow model for acoustic speech signals
No full textA new method "simultaneous inverse filtering and model matching" (SIM) is proposed that allows one to calculate voice source measures without any user interaction. It is based on the discrete all-pole modeling (DAP) technique for inverse filtering (IF), which is modified to include a model of the glottal flow as integral part [LF model, Fant ct al., STL-QPSR (Stockholm) 4/1985, 1-13 (1986)]. As the correct LF parameters are initially unknown, they are estimated in an iterative procedure using multi-dimensional optimization techniques that are initialized according to the results of an exhaustive search. The error criteria applied reflect how well the IF is performed after the spectral contribution of the glottal flow has been removed. The resulting optimal LF parameter constellation serves as the basis to calculate 11 voice source measures. The performance was evaluated using synthesized signals and recordings of natural utterances. For the synthesized signals, the accuracy to reproduce the original parameters was high (correlations exceeding 0.88) for measures where the starting point of the glottal cycle did not enter explicitly. Errors were smaller compared to conventional estimation methods where the measures were estimated from the IF signal. The analysis of natural utterances indicates that problems still exist with regard to robustness, but that under advantageous conditions the open quotient, the speed quotient, the closing quotient, the parabolic spectral parameter, and the negative peak amplitude of the glottal flow derivative can indeed be determined automatically by the SIM method. (C) 2001 Acoustical Society of America
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