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Retrieval analysis and principal variable analysis of 127 M2a-38 Mm™ metal on metal hip replacements
No full textBackgroundThe objective of this study was to investigate the factors which affected the material loss from 127 M2a-38 mm™ hip replacements.MethodsThe alignment and patient data was obtained for 127 patients. The explants bearings and tapers were measured to determine the level of material loss and their geometry.Results87 joints were edge wearing (EW), 28 normally wearing (NW) and 12 had edge interaction (EI). The NW joints were wearing at a mean bearing combined rate of 0.34 mm3/yr. For the NW joints, bearing clearance was linked to the bearing combined volumetric loss rate (r = 0.446). The rates of loss from the head's taper was 0.21 mm3/yr. Lower wearing and lower clearance joints had higher values of loss from the tapers. The taper loss from joints with a positive clearance were significantly higher (p = .026) than those with a negative clearance.ConclusionsThe results demonstrate that bearing loss rates for NW joints was as expected. The high number of joints showing signs of edge wearing resulted from low clearances and a low cup articular arc angle. The taper loss was lower than other similar joint designs with positive clearances resulting in greater loss.<br/
Retrieval and principle variable analysis of 127 M2a-38mm™ metal on metal hip replacements
No full textINTRODUCTION: The need to revise metal on metal (MoM) implants early due to adverse reaction to debris and corrosion products is a major concern within the orthopaedic community. However the in-vivo performance of these joints depends on a range of variables related to the patient, the joint design and the surgical positioning. These variables can impact on the performance of the bearing but also the taper interface in modular components, with both capable of metal debris and corrosion products capable of causing the adverse reactions and pain which results in the need for joint retrieval. The objective of this study was to investigate the design, alignment and patient specific factors which affected the level of material loss for the bearing surfaces and taper of a cohort of M2a-38mm™ MoM hip replacements.METHODS: The cohort consisted of 127 M2a-38mm™retrieved femoral head and acetabular components which had been paired with Bi-metric™ uncemented titanium stems. Each joint had patient specific data for the weight, height, BMI, age at Primary surgery, functional time. They also had positional data including neck angle, horizontal and vertical offset, neck length, cup inclination and version angles, the bearing clearance, the taper angle and taper clearance angle based on the perfect trunnion angle of the Bi-metric™ stem.Material loss analysis was undertaken on the femoral and acetabular bearing surfaces and the taper interface of the head using an OrthoLux (RedLux, Southampton, UK). In addition wear scar location on the bearings was analysed to differentiate the joints into one of three groups, either edge worn (EW), normally wearing (NW) or edge interaction (EI). The patient, implant and positional variables were compared to the material loss values using both Spearman and Pearson’s correlations so as to determine the variables having significant effects but also to account for linear and non-linear relationships.RESULTS SECTION: Based on the wear scar location classification the 28 joints were wearing normally, 12 had edge interaction and 87 showed signs of having been edge wearing. Table 1 shows the mean volumetric loss rates and ranges of the loss for the joints in the different classifications. The comparisons between the loss values and the independent variables showed a number of significant correlations but varied between the wear scar location groups. For the NW joints, only the bearing clearance was significantly linked to the femoral head volumetric loss rate (r = 0.419). The EW joints had a larger number of significant correlations. The femoral head volume loss was linked to both the bearing clearance (r = 0.379) and the version angle (r = 0.23) of the cup. The Acetabular cup loss was significantly correlated to the inclination and version angles of its placement (r = 0.35 and 0.44). For the EI group The Cup loss was linked to the vertical offset (r = -0.701) and the Neck length (r = -0.596).The taper loss wasn’t linked to any variables in the NW group, but was linked to the bearing clearance (r = 0.316), but also to the height (r = 0.331), weight (r = 0.29) and taper angle(r = 0.314) in the EW group and Weight (r = -0.756) in the EI group. While not showing any significance in correlation there was a visible effect of taper clearance angle on the taper failure with positive taper angles providing a higher level of loss than negative ones.DISCUSSION: This is one of the few studies to have reported the assessment of the loss from well aligned MoM bearings and demonstrates that when aligned well these M2a-38mm™ joints were wearing at the rate expected and below that of other joints1. There was only one significant correlation for the NW joints which was a positive one with the bearing clearance. This shows that the lower clearance joints had a lower level of loss than their higher clearance compatriots. This can be attributed to both the higher running in wear experienced by high clearance joints but also the potential for enhanced lubrication of the bearings at lower clearances. The highest levels of loss shown in the EW group are expected given the nature of the bearing contact. The positive correlation with clearance was maintained in this group as well. The loss values were predominantly linked to the acetabular cup positioning, however the correlations were less than r = 0.45 suggesting other factors not assessed in this study were having an effect. It was also notable that a number of joints classified as edge wearing fell within the ‘safe zone’ (Figure 1.).The levels of material loss from the tapers are lower than other comparable MoM joint designs2,3. The negativecorrelationto bearing clearancein both the EW and the cohort as a whole offsets the benefits seen to the bearing wear and suggests a transfer of load or torque to the interface as a result of the lower clearance.Taper loss was the onlyvariable which was linked to patient variable, with a weak but positive correlation to weight in the EW and whole cohort analysis.The positive taper angle effect is likely due to the production of a crevice environment and the more ready ability for the exchange of fluid and ions compared to the negative clearances. In conclusion, the NW joints showed levels of material loss which would be expected of these joints in-vivo and levels of taper loss which is below that reported from other similar joint designs. The major issue was the number of joints which exhibited edge wear or interaction which exacerbated the loss from the bearings. However, the variable analysis suggests that positioning explains only a portion of the loss values, with well aligned joints exhibiting edge wear.SIGNIFICANCE/CLINICAL RELEVANCE: This study is the largest single cohort analysis of this joint design.The control of the joint to a single design, size and stem design provided an opportunity to minimise the different variables between joints provided a unique ability to focus on those which are affecting their performance.REFERENCES:1. Morlock MM, J Bone Joint. Surg Am, Vol. 90, 2008:89-95.2.Langton DJ, Bone Joint Res 2012;1-4:56-63. 3.Matthies AK J Orthop Res 2013;31-11:1677-85..
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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