182 research outputs found
The EU's critical raw materials dilemma in Serbia and Bosnia-Herzegovina : taking stock and finding ways forward
No full textFrauke Seebass ; publishing department: Dialogue Southeast Europ
Strategische Anreizgestaltung
No full textDer vorliegende Beitrag untersucht die Anreizgestaltung in Unternehmen aus strategischer Perspektive. Im Vordergrund steht dabei die Frage, inwieweit unterschiedliche Anreize divergierende Interessen zwischen Mitarbeitern und mit dem Unternehmen ausgleichen können. In einem ersten Teil betrachten wir zunächst individuelle Anreize und zeigen auf, dass ein Spannungsverhältnis zwischen optimaler Anreizgestaltung und optimaler Risikoallokation besteht. Darüber hinaus wird diskutiert, warum ungünstig gewählte Bemessungsgrundlagen die Wertschöpfung eines Mitarbeiters senken können. Zudem werden weitere Aspekte individueller Anreizsetzung aufgegriffen, wie beispielsweise die Entlohnung von Managern. Im zweiten Teil des Beitrags werden dann Anreize für Gruppen vonMitarbeitern diskutiert. Wichtige Vorteile der relativen Leistungsbeurteilung werden aufgezeigt, aber auch der wesentliche Nachteil, nämlich dass Mitarbeiter keinen Anreiz mehr haben, sich gegenseitig zu helfen. Als mögliche Lösung hierfür wird die Teamentlohnung diskutiert, die allerdings zu Trittbrettfahrerproblemen führen kann
Author Commentary: Mobile Music Technology: From Innovation to Ubiquitous Use
No full textThis author commentary chapter accompanies the re-publication of my co-authored 2006 paper ‘Mobile Music Technology: Report on an Emerging Community’ - one of 30 papers selected from 1,200 NIME papers to be included in the book ‘A NIME Reader: Fifteen Years of New Interfaces for Musical Expression, published by Springer and edited by Alexander Refsum Jensenius and Michael J. Lyons
Current Approaches for Image Fusion of Histological Data with Computed Tomography and Magnetic Resonance Imaging
No full textClassical analysis of biological samples requires the destruction of the tissue’s integrity by cutting or grinding it down to thin slices for (Immuno)-histochemical staining and microscopic analysis. Despite high specificity, encoded in the stained 2D section of the whole tissue, the structural information, especially 3D information, is limited. Computed tomography (CT) or magnetic resonance imaging (MRI) scans performed prior to sectioning in combination with image registration algorithms provide an opportunity to regain access to morphological characteristics as well as to relate histological findings to the 3D structure of the local tissue environment. This review provides a summary of prevalent literature addressing the problem of multimodal coregistration of hard- and soft-tissue in microscopy and tomography. Grouped according to the complexity of the dimensions, including image-to-volume (2D ⟶ 3D), image-to-image (2D ⟶ 2D), and volume-to-volume (3D ⟶ 3D), selected currently applied approaches are investigated by comparing the method accuracy with respect to the limiting resolution of the tomography. Correlation of multimodal imaging could position itself as a useful tool allowing for precise histological diagnostic and allow the a priori planning of tissue extraction like biopsies
Author Correction: A shared neural basis underlying psychiatric comorbidity
No full textCorrection to: Nature Medicine. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Hervé Lemaître, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris and Sylvane Desrivières. The STRATIFY and ESTRA consortia are now combined to list Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Gareth J. Barker, Arun L. W. Bokde, Hervé Lemaître, Frauke Nees, Dimitri Papadopoulos Orfanos, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris, Henrik Walter, Robert Whelan, Sylvane Desrivières and Gunter Schumann as members, and the IMAGEN consortium is updated to also include Sylvane Desrivières. Affiliations, author contributions and acknowledgements have been updated to reflect the new authorship, and all changes have been made in the HTML and PDF versions of the article
Accurate Determination of Phenotypic Information from Historic Thoroughbred Horses by Single Base Extension
No full textHistoric DNA data have the potential to identify phenotypic information otherwise invisible in the historical, archaeological and palaeontological record. In order to determine whether a single nucleotide polymorphism typing protocol based on single based extension (SNaPshot?) could produce reliable phenotypic data from historic samples, we genotyped three coat colour markers for a sample of historic Thoroughbred horses for which both phenotypic and correct genotypic information were known from pedigree information in the General Stud Book. Experimental results were consistent with the pedigrees in all cases. Thus we demonstrate that historic DNA techniques can produce reliable phenotypic information from museum specimens
Zelluläre und subzelluläre Testsysteme zur Beurteilung des biologischen Gefährdungspotenzials von Chemikalien im nachhaltigen Chemikaliendesign.Konzept einer Teststrategie und ihre Anwendung in zwei Fallbeispielen
No full textGreen chemicals should display no or little toxicity for men and environment. But how can it be guaranteed that new chemicals meet these requirements? A concept was developed to assess in a quick and easy way the hazard potential of a chemical already during the design of this chemical. This assessment is based on cellular and sub-cellular test systems. In a first step the overall potential of a set of chemicals to interact with biological structures is assessed based on the T-SAR concept (thinking in terms of structure-activity relationships) and on tests with cell cultures. In a second step, specific interaction potentials are assessed. Based on the results of the first step a set of sub cellular test systems for specific interactions with biological structures such as enzyme inhibition is selected (flexible test battery). Results of both steps are included in a hazard potential profile. The concept was applied for two case studies using two biocides and a set of ionic liquids. Results show, that the concept allows a first assessment of the hazard potential of a chemical. However further test systems for specific interaction potentials need to be included
Population genetics of modern and ancient cattle
No full textTHESIS 9180The domestication of cattle was a milestone in human history. It is widely accepted
that cattle were domesticated in at least two independent domestication events; the
Fertile Crescent was the primary domestication centre for Bos taurus, while Bos indicus
was domesticated in the Indus Valley. However, a number of aspects of demographic
history, geography and timeline of cattle domestication are still unresolved
Author Correction: A shared neural basis underlying psychiatric comorbidity
No full textCorrection to: Nature Medicine https://doi.org/10.1038/s41591-023-02317-4. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Hervé Lemaître, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris and Sylvane Desrivières. The STRATIFY and ESTRA consortia are now combined to list Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Gareth J. Barker, Arun L. W. Bokde, Hervé Lemaître, Frauke Nees, Dimitri Papadopoulos Orfanos, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris, Henrik Walter, Robert Whelan, Sylvane Desrivières and Gunter Schumann as members, and the IMAGEN consortium is updated to also include Sylvane Desrivières. Affiliations, author contributions and acknowledgements have been updated to reflect the new authorship, and all changes have been made in the HTML and PDF versions of the article.</p
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