2,999 research outputs found
Norepinephrine-induced β<sub>1</sub>-adrenergic peripheral vasodilation in conscious dogs
No full text Page H49: Stephen F. Vatner, Delvin R. Knight, and Thomas H. Hintze. “Norepinephrine-induced β1-adrenergic peripheral vasodilation in conscious dogs.” Figure 1 and Figure 4 were reversed. The figures and their correct legends should appear as follows. (See PDF) </jats:p
Textbooks designed for students’ learning in the digital age
No full textKnight, BA ORCiD: 0000-0001-6627-378XIn this paper the author challenges the thoughts, practices and assumptions related to the creation, acquisition and use of textbooks and digital learning resources in the digital age. Firstly, the discussion centres on student characteristics in the culture of the knowledge society, and then examines the efficacy of
textbooks. Sophisticated Individualised Data Delivery Systems (SIDDS) (Knight 2015) are then introduced as the new “textbooks” to utilise the benefits of digital learning resources. The chapter will describe principles underpinning a learner-centred design framework as aspects to consider when designing learning experiences for diverse learners in textbooks incorporating new media formats (Fasso, Knight & Knight 2013)
Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol
No full textPurpose: to prospectively validate two risk scores to predict mortality (4C Mortality) and in-hospital deterioration (4C Deterioration) among adults hospitalised with COVID-19.Methods: prospective observational cohort study of adults (age ≥18 years) with confirmed or highly suspected COVID-19 recruited into the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) WHO Clinical Characterisation Protocol UK (CCP-UK) study in 306 hospitals across England, Scotland and Wales. Patients were recruited between 27 August 2020 and 17 February 2021, with at least 4 weeks follow-up before final data extraction. The main outcome measures were discrimination and calibration of models for in-hospital deterioration (defined as any requirement of ventilatory support or critical care, or death) and mortality, incorporating predefined subgroups.Results: 76 588 participants were included, of whom 27 352 (37.4%) deteriorated and 12 581 (17.4%) died. Both the 4C Mortality (0.78 (0.77 to 0.78)) and 4C Deterioration scores (pooled C-statistic 0.76 (95% CI 0.75 to 0.77)) demonstrated consistent discrimination across all nine National Health Service regions, with similar performance metrics to the original validation cohorts. Calibration remained stable (4C Mortality: pooled slope 1.09, pooled calibration-in-the-large 0.12; 4C Deterioration: 1.00, –0.04), with no need for temporal recalibration during the second UK pandemic wave of hospital admissions.Conclusion: both 4C risk stratification models demonstrate consistent performance to predict clinical deterioration and mortality in a large prospective second wave validation cohort of UK patients. Despite recent advances in the treatment and management of adults hospitalised with COVID-19, both scores can continue to inform clinical decision making.Trial registration number: ISRCTN66726260
Supplemental Material - Application and Extension of the Alcohol Recovery Narratives Conceptual Framework
No full textSupplemental Material for Application and Extension of the Alcohol Recovery Narratives Conceptual Framework by Mohsan Subhani, Usman Talat, Holly Knight, Joanne R. Morling, Katy A. Jones, Guruprasad P. Aithal, Stephen D. Ryder and Stefan Rennick-Egglestone in Qualitative Health Research</p
The Knight on the Threshold: a Thematic and Anthropological Study of the English Gawain Romances
No full textReview Essay: R. B. Dobson and J. Taylor. \u3ci\u3eRymes of Robyn Hood: An Introduction to the English Outlaw\u3c/i\u3e
No full textR. B. Dobson and J. Taylor. Rymes of Robyn Hood: An Introduction to the English Outlaw. Gloucestershire: Sutton Publishing, Ltd., 1997. 332 pp.
Stephen Knight and Thomas Ohlgren. Robin Hood and Other Outlaw Tales. Kalamazoo, MI: Medieval Institute Publications, 1997. 723 pp
Studies in Figured Tours of Knight in Two and Higher Dimensions
No full textTour of knight is over a millennium year old puzzle but ‘Figured tour’ of knight is a recent field of research. T. R. Dawson, an English chess problemist and the father of Fairy Chess, coined the term in 1940s. The name figured tour is appropriate for any numbered tour in which certain arithmetically related numbers are arranged in a geometrical pattern. Figured tours have been only looked into two-dimensional boards, mostly on 8x8 board. The author has constructed knight tour with square numbers in fiveleaper {3, 4} + {0, 5} path and various other figured tours on 6x6 board and extended it in three and four dimensional space. Construction of figured tours is a mathematical recreation and can also be used in pedagogy of higher mathematics
Potential use of Dicyphus hesperus Knight (Heteroptera: Miridae) for biological control of pests of greenhouse tomatoes
No full textThe potential of Dicyphus hesperus Knight as a predator of greenhouse whitefly, Trialeurodes vaporariorum (Westwood), and two-spotted spider mites, Tetranychus urticae Koch, was assessed in the laboratory and in a tomato greenhouse. D. hesperus adults fed readily upon both pest species in the laboratory, and nymphs completed development from egg to adult on either whitefly or mites. Whitefly, however, were a superior food for growth and development of D. hesperus compared to mites. Development time was shorter and resulting adult body size was larger for nymphs reared on whitefly compared to those reared on mites. In a greenhouse release, adults oriented to and oviposited on whitefly-infested sentinel plants but did not orient to mite-infested sentinel plants. D. hesperus adults oviposited on greenhouse tomatoes and their progeny completed development in a greenhouse in which both whitefly and mites were present. The results are discussed as they relate to the use of D. hesperus for biological control of pests of greenhouse vegetables.Peer reviewedFinal article publishedDicyphus hesperusgreenhouse vegetablestomatoomnivoresgeneralist predatorsHeteropterazoophytophagousTetranychus urticaeTrialeurodes vaporarioru
Wear in the prosthetic shoulder: association with design parameters
No full textTotal replacement of the glenohumeral joint provides an effective means for treating a
variety of pathologies of the shoulder. However, several studies indicate that the procedure
has not yet been entirely optimized. Loosening of the glenoid component remains the
most likely cause of implant failure, and generally this is believed to stem from either
mechanical failure of the fixation in response to high tensile stresses, or through osteolysis
of the surrounding bone stock in response to particulate wear debris. Many computational
studies have considered the potential for the former, although only few have
attempted to tackle the latter. Using finite-element analysis an investigation, taking into
account contact pressures as well as glenohumeral kinematics, has thus been conducted,
to assess the potential for polyethylene wear within the artificial shoulder. The relationships
between three different aspects of glenohumeral design and the potential for wear
have been considered, these being conformity, polyethylene thickness, and fixation type.
The results of the current study indicate that the use of conforming designs are likely to
produce slightly elevated amounts of wear debris particles when compared with less
conforming joints, but that the latter would be more likely to cause material failure of the
polyethylene. The volume of wear debris predicted was highly influenced by the rate of
loading, however qualitatively it was found that wear predictions were not influenced by
the use of different polyethylene thicknesses nor fixation type while the depth of wearing
was. With the thinnest polyethylene designs 2 mm the maximum depth of the wear scar
was seen to be upwards of 20% higher with a metal-backed fixation as opposed to a
cemented design. In all-polyethylene designs peak polymethyl methacrylate tensile
stresses were seen to reduce with increasing polyethylene thickness. Irrespective of the
rate of loading of the shoulder joint, the current study indicates that it is possible to
optimize glenoid component design against abrasive wear through the use of high conformity
designs, possessing a polyethylene thickness of at least 6 mm
Herald of Holiness Volume 40, Number 15 (1951)
No full text03 A Tribute to Our Founders By General Superintendent Williamson 04 Rev. Albert B. Riggs Assembled by Velma I. Knight 04 Spreading Scriptural Holiness By W. R. Lanpher 05 Epistle to the Ephesians IX: Sealed with the Spirit By H. Orton Wiley 05 His Messenger of Love By Frances B. Erickson 06 Thank God for Camp Meetings! By Robert E. Mortensen 06 Camp Meeting As a Pastor Sees It By James A. Young 07 Camp-Meeting Preaching By Jarrette Aycock 08 Think on These Things By F. Lincicome 08 I Seek Thy Ways By Pearl Burnside McKinney 09 God’s Remedy for Anxiety By Neil E. Hightower 10 Home Missions and Evangelism By Roy F. Smee 11 Our Students Speak 12 Editorials By Stephen S. White 14 The Sunday School Lesson by Norman R. Oke 14 Foreign Missions By Remiss Rehfeldt 15 The Question Box Conducted By Stephen S. White 16 Religious News and Comments Edited by Delbert R. Gish 16 The Home Circle Conducted by Grace Ramquist 17 News of the Churches 20 The Christian By Ora I. Clairess 23 Servicemen\u27s Cornerhttps://digitalcommons.olivet.edu/cotn_hoh/3251/thumbnail.jp
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