1,720,959 research outputs found
MSJ843055_supplemental_material – Supplemental material for Pregnancy outcomes in patients with multiple sclerosis treated with teriflunomide: Clinical study data and 5 years of post-marketing experience
No full textSupplemental material, MSJ843055_supplemental_material for Pregnancy outcomes in patients with multiple sclerosis treated with teriflunomide: Clinical study data and 5 years of post-marketing experience by Sandra Vukusic, Patricia K Coyle, Stephanie Jurgensen, Philippe Truffinet, Myriam Benamor, Salman Afsar, Annie Purvis, Elizabeth M Poole and Christina Chambers in Multiple Sclerosis Journal</p
Percentage of disabled RRMS subjects (EDSS score ≥3.5) with improvement in T25FW from best baseline walk over 30 months following randomization to natalizumab or placebo in the AFFIRM study: sensitivity analyses by consistency of improvement.
No full text<p><i>P</i> values assessing the difference between treatment groups based on two-sided Fisher exact test.</p><p>RRMS, relapsing-remitting multiple sclerosis; EDSS, Expanded Disability Status Scale; T25FW, timed 25-foot walk.</p
Percentage of T25FW responders over shorter-term (6–8 months) and longer-term (24–30 months) follow-up in disabled RRMS<sup>a</sup> and SPMS subjects during treatment with natalizumab compared with placebo or IM IFNβ-1a.
No full texta<p>Disabled RRMS subjects defined as those with EDSS ≥3.5 and T25FW >5 seconds at baseline.</p>b<p>In SENTINEL, subjects on IM IFNβ-1a for at least 12 months were randomized to adding natalizumab or placebo.</p><p>T25FW, timed 25-foot walk; RRMS, relapsing-remitting multiple sclerosis; SPMS, secondary progressive multiple sclerosis; IM, intramuscular; IFNβ-1a, interferon beta-1a; EDSS, Expanded Disability Status Scale.</p
Median change in T25FW over 2 years by baseline EDSS score in patients with SPMS.
No full text<p>Patients randomized to the placebo arm of the IMPACT study. T25FW, timed 25-foot walk; EDSS, Expanded Disability Status Scale; SPMS, secondary progressive multiple sclerosis.</p
Absolute and percentage change from baseline in T25FW between responders and nonresponders independent of treatment group over shorter-term (6–8 months) and longer-term (24–30 months) follow-up in disabled subjects with RRMS and SPMS.
No full texta<p>In seconds.</p><p>T25FW, timed 25-foot walk; RRMS, relapsing-remitting multiple sclerosis; SPMS, secondary progressive MS; SD, standard deviation.</p
Baseline subject characteristics.
No full texta<p>Number of relapses in prior 24 months for MS231.</p><p>MS, multiple sclerosis; SPMS, secondary progressive MS; RRMS, relapsing-remitting MS; IM, intramuscular; IFNβ-1a, interferon beta-1a; SD, standard deviation; EDSS, Expanded Disability Status Scale; Gd+, gadolinium enhancing; T25FW, timed 25-foot walk.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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