171 research outputs found
Umweltschutz als Wirtschaftsfaktor : Technologien zum Schutz von Klima und Umwelt haben großes Wachstumspotenzial
No full textDie Nachfrage nach Umweltschutztechnologien steigt. Der angewandten wirtschaftspolitischen Forschung kommt die Aufgabe zu, die ökonomischen Effekte des umweltpolitisch motivierten Handelns empirisch zu erfassen und auszuwerten. Dr. Birgit Gehrke, Dr. Ulrich Schasse und Prof. Stephan Thomsen vom Center für Wirtschaftspolitische Studien (CWS) und Institut für Wirtschaftspolitik zeigen, dass eine leistungsfähige Umweltschutzwirtschaft die Voraussetzung ist, damit Deutschland auch weiterhin an der wachsenden Nachfrage nach Umweltschutztechnologien partizipieren kann
Stadt-Theater in Düsseldorf / Die Gebrüder Foster, oder: Das Glück und seine Launen : Montag den 15. Januar 1855 ; Gastspiel des Herrn Hegel, vom Stadt-Theater zu Breslau ; Charactergemälde aus dem 15. Jahrhundert in 5 Aufzügen, nach einem englischen Plane
No full textvon Carl Töpfer. Personen: Herr Mädel, Herr Weidner, Frau Philippi, Herr Laschar, Stephan Foster - Herr Hegel als Gast, Frau Schindelmeißer, Herr Boden, Fräul. Hendrichs, Herr Gehrke, Herr Stotz, Herr Linden, Herr Derossi, Herr Philippi, Herr Artenbach, Herr Bürger, Herr Müller, Herr Kugler, Herr Morgenstern, Herr Pottschweid, Herr Fischer. E. Th. L'ArrongeIn Fraktu
Progress in Economics
No full textThe Author discusses the relevance of studying the progress made in economic research and how to assess the existence of different models
Representation of lattices with modal operators in two-sorted frames
No full textWe study general lattices with normal unary operators for which we prove relational representation and duality results. Similar results have appeared in print, using Urquhart's lattice representation, by the second author with Vakarelov, Radzikowska and Rewitzky. We base our approach in this article on the Hartonas and Dunn lattice duality, proven by Gehrke and Harding to deliver a canonical lattice extension, and on recent results by the first author on the relational representation of normal lattice operators. We verify that the operators at the representation level (appropriately generated by relations) are the canonical extensions of the lattice operators, in Gehrke and Harding's sense. © 2019 - IOS Press and the authors. All rights reserved
The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain.
No full textNotch (N) signaling is central to the self-renewal of neural stem cells (NSCs) and other tissue stem cells. Its deregulation compromises tissue homeostasis and contributes to tumorigenesis and other diseases. How N regulates stem cell behavior in health and disease is not well understood. Here we show that N regulates bantam (ban) microRNA to impact cell growth, a process key to NSC maintenance and particularly relied upon by tumor-forming cancer stem cells. Notch signaling directly regulates ban expression at the transcriptional level, and ban in turn feedback regulates N activity through negative regulation of the Notch inhibitor Numb. This feedback regulatory mechanism helps maintain the robustness of N signaling activity and NSC fate. Moreover, we show that a Numb-Myc axis mediates the effects of ban on nucleolar and cellular growth independently or downstream of N. Our results highlight intricate transcriptional as well as translational control mechanisms and feedback regulation in the N signaling network, with important implications for NSC biology and cancer biology
New attempts at Electronic Documents in Transport. Bolero - the end of the experiment, the beginning of the future?
No full textIn this thesis the author examines a 'revolution' taking place in the shipping industry brought on by the development of computerisation, electronic commerce and the change from paper documentation to electronic documentation in the carriage of goods by sea. The focus of the paper is on Bolero, a project of the European Community beginning in the early 1990s and which has been used commercially since September 1999. In this paper the author follows the Bolero project from its inception as an experiment through to its commercial application. The question is asked to what extent Bolero has become an alternative to, or in fact replaced paper documentation in the carriage of goods by sea. As an introduction the author looks at the paper bill of lading and other forms of sea transport documentation with a focus on their advantages and disadvantages. He then examines the development of EDI and paperless sea transport documentation, in particular Bolero and the history of its development. Following this is an in depth investigation of the Bolero system in its current form, the contractual relations involved and the position of Bolero in the surrounding legal framework in a South African and international context. Finally the author looks at the future of Bolero as a commercial enterprise
Lecture versus discussion in the study of sophomore library skills
No full textThe purpose of this study was to determine which method of instruction--the lecture or the small group discussion--would achieve the best learning results as far as knowledge of certain unfamiliar materials was concerned.
Specifically, the author of this research study tried to answer this questions When an instructor is teaching selected reference books to average-ability sophomores in an English 10 library skills unit at Fort Dodge Senior High School, Fort Dodge, Iowa, which method of instruction--the lecture or the small group discussion--will achieve the best learning results as measured by an author- constructed post-test?
In this research study the author predicted a null hypothesis, no significant difference in student learning achievement as measured by an author-constructed post-test in English 10 library skills unit of selected reference books will be found between the lecture and the small group discussion methods of teaching
MV-algebras, Grothendieck toposes and applications
No full text2014 - 2015This thesis is a contribution to the research program ‘toposes as bridges’ introduced in [12],
which aims at developing the unifying potential of the notion of Grothendieck topos as a means
for relating different mathematical theories to each other through topos-theoretic invariants.
The general methodology outlined therein is applied here to study already existing categorical
equivalences of particular interest arising in the field of many-valued logics and also to produce
new ones. The original content of the disseration is contained in [22], [21] and [23]... [edited by Author]XIV n.s
Monitoring of tumor burden in vivo by optical imaging in a xenograft SCID mouse model: evaluation of two fluorescent proteins of the GFP-superfamily.
No full textBackground Mouse models of human-malignant-melanoma (MM) are important tools to study tumor dynamics. The enhanced green fluorescent protein (EGFP) is widely used in molecular imaging approaches, together with optical scanners, and fluorescence imaging. Purpose Currently, there are no data available as to whether other fluorescent proteins are more suitable. The goal of this preclinical study was to analyze two fluorescent proteins of the GFP superfamily under real-time in vivo conditions using fluorescence reflectance imaging (FRI). Material and Methods The human melanoma cell line MeWo was stable transfected with one plasmid: pEGFP-C1 or pDsRed1-N1. We investigated two severe combined immunodeficiency (SCID)-mice groups: A (solid xenografts) and B (xenografts as metastases). After three weeks, the animals were weekly imaged by FRI. Afterwards the mice were euthanized and metastases were imaged in situ: to quantify the cutis-dependent reduction of emitted light, we compared signal intensities obtained by metastases in vivo with signal intensities obtained by in situ liver parenchyma preparations. Results More than 90% of cells were stable transfected. EGFP-/DsRed-xenograft tumors had identical growth kinetics. In vivo the emitted light by DsRed tumors/metastases was much brighter than by EGFP. DsRed metastases were earlier (3 vs. 5 weeks) and much more sensitive detectable than EGFP metastases. Cutis-dependent reduction of emitted light was greater in EGFP than in DsRed mice (tenfold). Autofluorescence of DsRed was lower than of EGFP. Conclusion We established an in vivo xenograft mouse model (DsRed-MeWo) that is reliable, reproducible, and superior to the EGFP model as a preclinical tool to study innovative therapies by FRI under real-time in vivo conditions
Simultaneous Improvement of Schooling and the Education of Teachers: Creating a Collaborative Consciousness
No full textBased on her experience in creating a professional development center-a school-university project to improve middle schools and create appropriate professional programs for middle school teachers-theauthor examines three dysfunctional attitudes in such collaborative efforts: the Trophy Mentality; the Education-as-Entrepreneurship Mindset; and the "I\u27m Okay, You\u27re Okay" Frame of Mind. To change the three attitudes, the author suggests using three tools: careful selection of incoming participants, education for skills and attitudes of collaboration, and socialization to the collaborative roles through role modeling and rewards
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