27 research outputs found
De woonvisie en de woningwet
No full textDe Woonvisie toegelicht: woningmarkt, woningbouw, woonomgevin
Leak-off of oil-based drilling fluids in saturated porous media: A CT scan-aided study
No full textThe static leak-off of oil-based drilling mud into liquid-saturated cores was studied experimentally. A simple model for the leak-off was first developed extending an earlier model for the static filtration into unsaturated core. CT scan aided static filtration experiments were performed in brine and oil and brine saturated cores, simulating reservoir saturation regimes. Formation of external filter cake and internal filtration of solid particles were visualized and leak-off volumes were determined as function of time. At the end of the experiments the formed external filter cake and internal particle deposition were characterised with the aid of an Electron Scanning Microscope. Using drilling fluids containing carbonate particles it was found that leak-off volumes for saturated cores are larger than for unsaturated cores. It was observed further that leak-off volumes increase with the particle size, i.e. consistently with a more permeable external filter cake and limited internal filtration. Leak-off volumes decreased when using smaller hematite particles or using larger range of (barite) particles sizes. The filtration volumes for the smaller sized drilling fluid components in brine saturated core experiments were found to be larger than filtration volumes found for dry core experiments in previous work.Petroleum EngineeringGeoscience & EngineeringCivil Engineering and Geoscience
The case of the golden background, a virtual restoration and a physical reconstruction of the medieval Crucifixion of the Lindau Master (c. 1425)
No full textModern and Contemporary Studie
Subacute Combined Spinal Cord Degeneration by Recreational Laughing Gas (NO) Use
No full textBackground: A few young patients were brought in with subacute combined spinal cord degeneration at the Department of Neurology in our hospital. They all have used laughing gas for recreational purposes. Case: A 30-year-old woman, known with alcohol abuse, was presented to our Department of Neurology for having paresthesia and unstable movements of arms, legs, and trunk for 9 days. She has used 50 laughing gas patterns per day. The diagnosis of laughing gas–induced combined spinal cord degeneration was evident by the low count of vitamin B 12 combined with lesions shown on magnetic resonance imaging (MRI). Abstaining from the laughing gas, weekly intramuscular injections of hydroxocobalamin and revalidation, she was fully recovered in 8 weeks. Conclusions: Recreational use of laughing gas seems to be more used in our society, however, without having any knowledge of the neurological consequences. The right diagnosis and treatment can provide full recovery in these patients. Furthermore, attention for this diagnosis can help increase social awareness
Daily negative interactions and mood among patients and partners dealing with multiple sclerosis (MS): The moderating effects of emotional support
No full textNegative interactions with intimate partners may have adverse consequences for well-being, especially for individuals dealing with chronic illness. However, it is not clear whether negative interactions affect both dimensions of positive and negative well-being and factors that may moderate this effect have not been well-described. The aim of the present study was to examine the association between daily received negative responses from the partner and end-of-day positive and negative mood in patients with multiple sclerosis (MS) and their intimate partners. Further, the moderating role of receiving emotional support from the partner on the same day was examined. Sixty-one MS patients and their intimate partners were approached via one MS centre and the neurology department of one hospital in the Netherlands and completed computerized diaries for 14 days. Both partners filled out diaries at the end of each day, recording received negative responses, emotional support and end-of-day positive and negative mood. In line with a domain specific model, patients or partners who reported receiving negative responses on a day had higher end-of-day negative mood, whereas received negative responses were unrelated to end-of-day positive mood. Further, for both patients and partners, the adverse effect of received negative responses on end-of day mood was moderated by receiving emotional support on the same day.Negative interactions Emotional support Multiple sclerosis Diary method Couples Mood
Primary cerebral immunoglobulin light chain amyloidoma in a patient with multiple sclerosis
No full textA man in his 60s, known with multiple sclerosis, presented with seizures and paresis of the left arm and leg. Brain imaging showed a white matter lesion, right parietal, which was progressive over the last 6 years and not typical for multiple sclerosis. Brain biopsy showed a B-cell infiltrate with IgA lambda monotypic plasma cell differentiation and amyloid deposits, typed as lambda immunoglobulin light chain (AL). Bone marrow biopsy and PET/CT ruled out a systemic lymphoma. Extended history taking, blood and urine testing (including cardiac biomarkers) identified no evidence of systemic amyloidosis-induced organ dysfunction.Primary cerebral AL amyloidoma is a very rare entity where optimal treatment is difficult to assess. The patient was treated with locally applied volumetric modulated arc radiotherapy, 24 Gy, divided in 12 fractions. Afterwards, the paresis of the left arm partially resolved, and the function of the left leg improved. Seizures did not occur anymore
Daily negative interactions and mood among patients and partners dealing with multiple sclerosis (MS): the moderating effects of emotional support.
No full textContains fulltext :
51991.pdf (Publisher’s version ) (Closed access)Negative interactions with intimate partners may have adverse consequences for well-being, especially for individuals dealing with chronic illness. However, it is not clear whether negative interactions affect both dimensions of positive and negative well-being and factors that may moderate this effect have not been well-described. The aim of the present study was to examine the association between daily received negative responses from the partner and end-of-day positive and negative mood in patients with multiple sclerosis (MS) and their intimate partners. Further, the moderating role of receiving emotional support from the partner on the same day was examined. Sixty-one MS patients and their intimate partners were approached via one MS centre and the neurology department of one hospital in the Netherlands and completed computerized diaries for 14 days. Both partners filled out diaries at the end of each day, recording received negative responses, emotional support and end-of-day positive and negative mood. In line with a domain specific model, patients or partners who reported receiving negative responses on a day had higher end-of-day negative mood, whereas received negative responses were unrelated to end-of-day positive mood. Further, for both patients and partners, the adverse effect of received negative responses on end-of day mood was moderated by receiving emotional support on the same day
Overview of numbers and percentages of mild, moderate, and severe adverse events according to relationship to INFb-1a treatment.
No full text<p>Overview of numbers and percentages of mild, moderate, and severe adverse events according to relationship to INFb-1a treatment.</p
Most common likely or definitely INFb-1a-related adverse events by body system in 275 patients.
No full text<p>N, number of patients; n, number of events;</p><p>*, in at least 4 patients; totalling 371 (95.6%);</p>†<p>, patients could have events in more than one category.</p
