1,720,969 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Διερεύνηση της ετήσιας επίπτωσης της Langerhans Cell Histiocytosis (LCH) και του επιπολασμού της γονιδιακής μετάλλαξης BRAF σε ενήλικες Έλληνες ασθενείς με LCH
Get PDFΗ ιστιοκυττάρωση Langerhans (LCH) αποτελεί μία σπάνια διαταραχή που χαρακτηρίζεται από διήθηση των ιστών από κύτταρα που προσομοιάζουν στα κύτταρα Langerhans, μία υποκατηγορία δενδριτικών κυττάρων που βρίσκεται στο δέρμα και τους βλεννογόνους. Η νόσος μπορεί να προσβάλει οποιοδήποτε όργανο εκτός από την καρδιά και τους νεφρούς και κατηγοριοποιείται ως φλεγμονώδες μυελοειδές νεόπλασμα με μεταλλάξεις στο μονοπάτι MAPK/ERK να ανευρίσκονται στο σύνολο των ιστολογικών διαγνώσεων της νόσου. Η μετάλλαξη BRAFV600E αποτελεί την συχνότερα εντοπιζόμενη με τη συχνότητα της να φτάνει το60% στους παιδιατρικούς πληθυσμούς, στους οποίους αναφέρεται συσχέτιση της με την εντόπιση, την έκταση και την βαρύτητα της νόσου.Η LCH έχει διαγνωσθεί σε όλες τις ηλικιακές ομάδες, αλλά παγκοσμίως συναντάται συχνότερα στα παιδιά με μέση ηλικία διάγνωσης τα 3 έτη, με μία εκτιμώμενη ετήσια επίπτωση έως 8.9 περιπτώσεις ανά εκατομμύριο πληθυσμού σε παιδιά κάτω των 15 ετών. Στους ενήλικες η νόσος είναι σπανιότερη και θεωρείται ''ορφανή νόσος'' με εκτιμώμενη επίπτωση από τα παιδιατρικά δεδομένα 1-2 περιπτώσεις ανά εκατομμύριο πληθυσμού ετησίως και μέση ηλικία διάγνωσης τα 33 έτη χωρίς οι ανωτέρω εκτιμήσεις να έχουν επιβεβαιωθεί μέσω μίας οργανωμένης επιδημιολογικής μελέτης στον ενήλικο πληθυσμό.Σκοπός της παρούσας διδακτορικής διατριβής είναι η προοπτική καταγραφή, για πρώτη φορά στη βιβλιογραφία, της ετήσιας επίπτωσης της LCH στους ενήλικες και η διερεύνηση του επιπολασμού της μετάλλαξης BRAFV600E στον ενήλικο Ελληνικό πληθυσμό καθώς και η συσχέτιση αυτής με κλινικό-εργαστηριακά δεδομένα, όπως η έκταση της νόσου, η ηλικία κατά τη διάγνωση, το φύλο, η προσβολή οργάνων, η ανταπόκριση στην αρχική θεραπεία (χημειοθεραπεία, χειρουργική εκτομή, διακοπή καπνίσματος, τοπική ακτινοθεραπεία ή συνδυαστική θεραπεία), η παρουσία άποιου διαβήτη, το ιστορικό κακοήθειας και ο κίνδυνος υποτροπής.Η καταγραφής των νέων περιπτώσεων LCH πραγματοποιήθηκε από την 1η Σεπτεμβρίου 2018 έως τις 31 Αυγούστου 2019 μέσω τακτικής επικοινωνίας με τα παθολογοανατομικά εργαστήρια που λειτουργούν στο Ελληνικό Σύστημα Υγείας, φθάνοντας συνολικά σε ποσοστό κάλυψης το 85%. Η ετήσια επίπτωση της LCH μεταξύ των ενηλίκων στην Ελλάδα υπολογίστηκε σε 1,58 ανά εκατομμύριο πληθυσμού ανά έτος, με μέση ηλικία διάγνωσης τα 43,5 έτη και αναλογία θήλεων / αρρένων 1.34.Η μετάλλαξη BRAF V600E ανευρέθηκε στο 39% των ασθενών της κλινικής ενηλίκων με LCH που έλαβαν μέρος στη μελέτη. Συγκεκριμένα, κατόπιν έγγραφης συγκατάθεσης, απομονώθηκε DNA από 40 κύβους παραφίνης, εκ των οποίων 31 απέδωσαν επαρκές υλικό για περαιτέρω ανάλυση με PCR. Η μετάλλαξη BRAFV600E εντοπίστηκε σε 12 ασθενείς (38.71%) με επικράτηση των γυναικών (83.3%), ενώ 13 ασθενείς (41.94%) δεν έφεραν τη μετάλλαξη. Σε 6 ασθενείς (2 άνδρες), (19.35%), η qPCR μελέτη του BRAFV600E δεν πληρούσε τα τεχνικά πρότυπα που απαιτούνται για την οριστική ερμηνεία των αποτελεσμάτων.Δεν υπήρξε στατιστικά σημαντική συσχέτιση της παρουσίας της μετάλλαξης με την ηλικία κατά τη διάγνωση, τη συμμετοχή συγκεκριμένων οργάνων, την έκταση της νόσου (μονοσυστηματική ή πολυσυστηματική), την ανταπόκριση στην αρχική θεραπεία, την ανάπτυξη άποιου διαβήτη και τον κίνδυνο υποτροπής.Καθώς οι νεότερες θεραπευτικές παρεμβάσεις στοχεύουν σε μοριακά μονοπάτια της νόσου απαιτούνται περαιτέρω μελέτες για τον εντοπισμό ολόκληρου του φάσματος μεταλλάξεων που σχετίζονται με την παθογένεια της νόσου και τις κλινικές της εκδηλώσεις.Langerhans cell histiocytosis (LCH) is a rare condition, characterized by tissue infiltration with cells that resemble Langerhans cells, a specialized subset of dendritic cells, which populates the epidermal layer of the skin and the mucosal tissues. LCH can affect any organ and is considered an inflammatory myeloid neoplasm with mutations in the MAPK/ERK pathway being found in all histological examinations. The BRAFV600E is the most common mutation, with a frequency of up to 60% in pediatric studies and an association with the disease extent, number of affected systems and severity of clinical manifestations.LCH is diagnosed in all age groups, but is most commonly seen in children with a mean age of diagnosis at 3 years old and an estimated annual incidence of up to 8.9 cases per million population in children under 15 years old. In adults the disease is rarer and is considered an ''orphan disease'' with an estimated incidence of 1-2 cases per million population and mean age at diagnosis at 33 years old. However, this estimated annual incidence hasn't been further investigated through an organized epidemiological study in the adult population.The aim of this research study is the prospective recording of the annual incidence of LCH in adults for the first time in literature and the investigation of the presence of the BRAFV600E mutation in Greek adults with LCH as well as its association with clinical parameters, such as the disease extent, age at diagnosis, gender, organ involvement, response to initial treatment (chemotherapy, surgical excision, smoking cessation, local radiotherapy or combination therapy), presence of diabetes insipidus, history of malignancy and relapse risk.The recording of new cases took place from the 1st of September 2018 until the 31st of August 2019 after frequent communication with the vast majority of pathology laboratories in theNational Health System in Greece (85%). The annual incidence of the disease in adults in Greece was estimated at 1.58 per million population with a mean age at diagnosis at 43.5 years and a female to male ratio of 1.34.The BRAF V600E mutation was found in 39% of the patients who are followed up in the LCH adult clinic and agreed to take part in the study. Upon written consent, DNA was isolated from 40 formalin fixed, paraffin-embedded tissue blocks, of which 31 yielded sufficient DNA for molecular analysis with PCR. The BRAFV600E mutation was found in 12 patients (38,71%) with the majority being females (83.3%), while 13 patients (41,94%) did not carry the mutation. In 6 patients (2 men), (19,35%), genotyping qPCR studies failed to meet the technical standards required for definitive interpretation of results.There was no statistically significant association of the presence of the mutation with age at diagnosis, organ involvement, disease extent (single system or multi-system), response to initial treatment, development of diabetes insipidus and relapse risk.As targeted therapies become more widespread in the management of LCH, further studies are needed for the discovery of the full spectrum of mutations implicated in disease pathogenesis
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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