87,291 research outputs found
I casi pilota
No full textI paragrafi "Risorse imprenditoriali" ed "Energia grigia" (p. 72-74) sono stati scritti con Nadia Battaglio; "Produzione di energia da fonti rinnovabili" (p. 74-90) con Francesco Stassi; "Ranco Sotto, occasione di sperimentazione" (p. 91-99) con Nadia Battaglio; "Caso studio valle Varaita" (p. 100-105) con Francesco Stassi
I casi pilota
No full textI paragrafi "Risorse imprenditoriali" ed "Energia grigia" (p. 72-74) sono stati scritti con Nadia Battaglio; "Produzione di energia da fonti rinnovabili" (p. 74-90) con Francesco Stassi; "Ranco Sotto, occasione di sperimentazione" (p. 91-99) con Nadia Battaglio; "Caso studio valle Varaita" (p. 100-105) con Francesco Stassi
Il ruolo della ERCP nell’era della colecistectomia videolaparoscopica. Nostra esperienza
No full textCalorimetric investigations on the metabolism of Bacillus strains isolated from artistic stoneworks
No full textIn the study on the deterioration of artistic stoneworks the possibility to relieve the presence of deteriorative microorganisms on the alterations is becoming evermore important. The spore-forming microorganisms belonging to Bacillus genus are often present in the biological alterations; these bacteria are very common and their caracteristic habitat is the soil, but they are also isolated from different other matrices, as the altered stone of monuments. Their role in the biodeterioration is particularly important for the capability to produce resistant forms, the spores, that permit the resistance to stressing envirnmental conditions. The aim of this work is to study the calorimetric behaviour and characterize the various phases of the cellular cycle of different Bacillus strains isolated from stonework alterations (B.cereus, B.subtilis e B. alvei) and verify if it is possible to obtain from the calorimetric signals significant differences that permit the marking of the single specie. Furthermore in every test carried out using spores a fall of the calorimetric signal results more evident, compared to tests performed with vegetative cells
Imprenditorialità e contesto: il caso italiano
No full textIl saggio affronta il problema storico di collocare gli imprenditori italiani nel loro ambiente, rappresentato dal peculiare contesto sociale, economico e politico italiano
Colorectal cancer stem cells and cell death.
No full textNowadays it is reported that, similarly to other solid tumors, colorectal cancer is sustained by a rare subset of cancer stem-like cells (CSCs), which survive conventional anticancer treatments, hanks to efficient mechanisms allowing escape from apoptosis, triggering tumor recurrence. To improve patient outcomes, conventional anticancer therapies have to be replaced with specific approaches targeting CSCs. In this review we provide strong support that BMP4 is an innovative therapeutic approach to prevent colon cancer growth increasing differentiation markers expression and apoptosis. Recent data suggest that in colorectal CSCs, protection from apoptosis is achieved by interleukin-4 (IL-4) autocrine production through upregulation of antiapoptotic mediators, including survivin. Consequently, IL-4 neutralization could deregulate survivin expression and localization inducing chemosensitivity of the colon CSCs pool. © 2011 by the authors; licensee MDPI, Basel, Switzerland
Epithelial-mesenchymal transition: a new target in anticancer drug discovery
No full textThe conversion of cells with an epithelial phenotype into cells with a mesenchymal phenotype, referred to as epithelial-mesenchymal transition, is a critical process for embryonic development that also occurs in adult life, particularly during tumour progression. Tumour cells undergoing epithelial-mesenchymal transition acquire the capacity to disarm the body's antitumour defences, resist apoptosis and anticancer drugs, disseminate throughout the organism, and act as a reservoir that replenishes and expands the tumour cell population. Epithelial-mesenchymal transition is therefore becoming a target of prime interest for anticancer therapy. Here, we discuss the screening and classification of compounds that affect epithelial-mesenchymal transition, highlight some compounds of particular interest, and address issues related to their clinical application
Output field-quadrature measurements and squeezing in ultrastrong cavity-QED
No full textWe study the squeezing of output quadratures of an electro-magnetic field escaping from a resonator coupled to a general quantum system with arbitrary interaction strengths. The generalized theoretical analysis of output squeezing proposed here is valid for all the interaction regimes of cavity-quantum electrodynamics: from the weak to the strong, ultrastrong, and deep coupling regimes. For coupling rates comparable or larger then the cavity resonance frequency, the standard input–output theory for optical cavities fails to calculate the variance of output field-quadratures and predicts a non-negligible amount of output squeezing, even if the system is in its ground state. Here we show that, for arbitrary interaction strength and for general cavity-embedded quantum systems, no squeezing can be found in the output-field quadratures if the system is in its ground state. We also apply the proposed theoretical approach to study the output squeezing produced by: (i) an artificial two-level atom embedded in a coherently-excited cavity; and (ii) a cascade-type three-level system interacting with a cavity field mode. In the latter case the output squeezing arises from the virtual photons of the atom-cavity dressed states. This work extends the possibility of predicting and analyzing the results of continuous- variable optical quantum-state tomography when optical resonators interact very strongly with other quantum systems
Il progetto pilota
No full textI paragrafi "Esempio applicativo di rilievo costruttivo finalizzato al recupero antisismico" (p. 52-55) e "Indicazioni preliminari per il consolidamento" (p. 55-56) sono di Corrado Curt
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