405 research outputs found
De. Condictione L. Si quis Conductionis. 25. C. de locato conducto. Sub Praesidio Dn. Andreae Mylii ... Publice disputabit. Author. Johann Gottfried Schönfeld/ Zitt. Lus. die 11. Iunii. M.DC.XCVI.
No full textDE. CONDICTIONE L. SI QUIS CONDUCTIONIS. 25. C. DE LOCATO CONDUCTO. SUB PRAESIDIO DN. ANDREAE MYLII ... PUBLICE DISPUTABIT. AUTHOR. JOHANN GOTTFRIED SCHÖNFELD/ ZITT. LUS. DIE 11. IUNII. M.DC.XCVI.
De. Condictione L. Si quis Conductionis. 25. C. de locato conducto. Sub Praesidio Dn. Andreae Mylii ... Publice disputabit. Author. Johann Gottfried Schönfeld/ Zitt. Lus. die 11. Iunii. M.DC.XCVI. (1)
Titelblatt (1)
Cap. I. - IV. (3)
Cap. V. - IIX. (13
Tractatio Iuris Publici De Serenissimis Potentissimisque Ducibus Brunsvicensibus Et Luneburgensibus / D.O.M.A. Praeside ... Dn. Joh. Ulrico Pregizero ... In Illustri Collegio Ad Diem 10. Decembr. Placido Eruditorum Examini sistit Author Christian Ulrich Blum
No full textTRACTATIO IURIS PUBLICI DE SERENISSIMIS POTENTISSIMISQUE DUCIBUS BRUNSVICENSIBUS ET LUNEBURGENSIBUS / D.O.M.A. PRAESIDE ... DN. JOH. ULRICO PREGIZERO ... IN ILLUSTRI COLLEGIO AD DIEM 10. DECEMBR. PLACIDO ERUDITORUM EXAMINI SISTIT AUTHOR CHRISTIAN ULRICH BLUM
Tractatio Iuris Publici De Serenissimis Potentissimisque Ducibus Brunsvicensibus Et Luneburgensibus / D.O.M.A. Praeside ... Dn. Joh. Ulrico Pregizero ... In Illustri Collegio Ad Diem 10. Decembr. Placido Eruditorum Examini sistit Author Christian Ulrich Blum (1)
Titelblatt (1)
Prooemium. (3)
Caput I. (5)
Caput II. (9)
Caput III. (12)
Caput IV. (22)
Caput V. (29)
Caput VI. (47)
I. - V. (54
Exegesis theologico-philologica duplicis messiae theanthrōpou egressus : Mich. V. v. 1
No full textquam ... sub praesidio Dn. Samuelis Leemanni ... publicae ac placidae disquisitioni subiicit Iohannes Herport, Helv. Bernas ... author & respondens, ad diem Ianuar. ...Diss. Hohe Schule Bern, 170
Dissertatio Iuridica De Praeferentia Creditorum In Concursu, Eorundemque Privilegiis
No full textQuam ... Praeside Dn. Georgio Wernero, ICto, ... Pro virili publice tuebitur Henrich Eberhard von Anderten/ Author & Respondens Ad diem V. Augusti In Maiori Novi Iulei Auditori
Unique crack propagation of double network hydrogels under high stretch
No full textDouble network (DN) gels, consisting of two contrasting interpenetrated polymer networks, exhibit large resistances to crack initiation and propagation. For practical applications, crack resistances of materials in highly stretched states are important. In this study, we investigated the crack growth behaviors of DN gels in stretched states by inducing crack seeds into these gels under various degrees of tension. This examination enables the analysis of crack propagation for a wide range of bulk energy release rate G. The power-law elationship between G and crack growth velocity v was investigated for DN gels with different tensile behaviors. We found that for brittle and unnecking DN gels, the velocities changed from slow mode (quasi-stationary fracture) to fast mode (dynamic fracture) with an increase in G, similar to that of a single network gel; in contrast, for necking DN gels having higher crack resistances than those of the unnecking DN gels, only fast modes were observed once the G is above a threshold. Real-time birefringence observation reveals a large damage zone around the crack tip at G slightly lower than the threshold, while the damage zone is hardly observed at G higher than the threshold. The results indicate that, for the necking DN gels, crack initiation has a large energy barrier owing to the formation of the damage zone; once this barrier is overcome, the excess energy release accelerates the crack propagation and therefore the gels exhibit dynamic fracture
Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes
No full textSummaryAlternative splicing (AS) defects that adversely affect gene expression and function have been identified in diabetic hearts; however, the mechanisms responsible are largely unknown. Here, we show that the RNA-binding protein RBFOX2 contributes to transcriptome changes under diabetic conditions. RBFOX2 controls AS of genes with important roles in heart function relevant to diabetic cardiomyopathy. RBFOX2 protein levels are elevated in diabetic hearts despite low RBFOX2 AS activity. A dominant-negative (DN) isoform of RBFOX2 that blocks RBFOX2-mediated AS is generated in diabetic hearts. DN RBFOX2 interacts with wild-type (WT) RBFOX2, and ectopic expression of DN RBFOX2 inhibits AS of RBFOX2 targets. Notably, DN RBFOX2 expression is specific to diabetes and occurs at early stages before cardiomyopathy symptoms appear. Importantly, DN RBFOX2 expression impairs intracellular calcium release in cardiomyocytes. Our results demonstrate that RBFOX2 dysregulation by DN RBFOX2 is an early pathogenic event in diabetic hearts
Double Dissociation Between Severe Cipo, Mild Neurological, And Severe Neuroradiological Findings: Presentation Of 6 Cases Of Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)
No full textInhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion
No full textThe large-Maf transcription factor v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MafA) has been found to be crucial for insulin transcription and synthesis and for pancreatic beta-cell function and maturation. However, insights about the effects of small Maf factors on beta-cells are limited. Our goal was to elucidate the function of small-Maf factors on beta-cells using an animal model of endogenous small-Maf dysfunction. Transgenic (Tg) mice with beta-cell-specific expression of dominant-negative MafK (DN-MafK) experiments, which can suppress the function of all endogenous small-Mafs, were fed a high-fat diet, and their in vivo phenotypes were evaluated. Phenotypic analysis, glucose tolerance tests, morphologic examination of beta-cells, and islet experiments were performed. DN-MafK-expressed MIN6 cells were also used for in vitro analysis. The results showed that DN-MafK expression inhibited endogenous small-Maf binding to insulin promoter while increasing MafA binding. DN-MafK Tg mice under high-fat diet conditions showed improved glucose metabolism compared with control mice via incremental insulin secretion, without causing changes in insulin sensitivity or MafA expression. Moreover, up-regulation of insulin and glucokinase gene expression was observed both in vivo and in vitro under DN-MafK expression. We concluded that endogenous small-Maf factors negatively regulates beta-cell function by competing for MafA binding, and thus, the inhibition of small-Maf activity can improve beta-cell function
Quetzalcóatl.- Los dos templos que sucesivamente tuvo en Cholula, estado de Puebla.. Anales del Museo Nacional de Arqueología, Historia y Etnografía. Num. 26 Tomo I (1934) Quinta Época (1934-1938)
No full textAcosta, José de. Historia Natural y Moral de las Indias, en que se tratan las cosas notables del cielo y elementos, metales, plantas, etc. - Sevilla, 1590, en 4o.Anales de Cuauhtitlán. Anales antiguos de México y sus contornos. Traducción del Sr. Dn. Faustino Chimalpopoca y otros.Bandelier, A. F. Report of an Archaeological Tour in Mexico in 1881. - Boston, 1884 (Papers of the Archaeological lnstitute of America, American Series. II.).Cortés, Hernán. Cartas de Relación a Carlos V. Madrid, 1930.Díaz del Castillo, Bernal. Historia Verdadera de la Conquista de Nueva España. Edición Genaro García. México, 1904.Mendieta, Fray Gerónimo de. Historia Eclesiástica Indiana escrita a fines del siglo XVI y la publica por primera vez Dn. Joaquín García Icazbalceta. México, 1870, en 4o.Motolinia, Toribio de Benavente. Historia de las Indias de Nueva España. Colección de Documentos, por Dn. Joaquín García Icazbalceta. Tomo l. México, 1858.Orozco y Berra, Manuel. Historia Antigua y de la Conquista de México. 4 vols. y atlas. México, 1880.Sahagún. Fr. Bernardino de. Historia General de las Cosas de Nueva España. Edición de Dn. Carlos María Bustamante. México, 1829.Solís, Antonio de. Historia de la Conquista de México, población y progresos de la América Septentrional conocida por el nombre de Nueva España. Nueva Edición enriquecida con diversas estampas y aumentada con la vida del autor, que escribió Dn. Juan de Goyeneche. En Amberes, en casa de Juan Bautista Verdussen. 1704. Con privilegio del Rey.Peñafiel, Antonio. Ciudades Coloniales y Capitales de la República Mexicana. Las cinco ciudades coloniales de Puebla, Cholula, Huexotzingo, Tepeaca, Atlixco y Tehuacán. - México de 1914
Magnetic double-network composite capable of large recoverable deformation
No full textThis paper presents the design and fabrication of a magnetic double network (DN) composite, which consists of permanent magnet chains embedded in an elastomer matrix, and was capable of large yet fully recoverable deformation. The initially connected magnets served as reusable sacrificial components in the composite. The strong magnetic attraction between neighboring magnetics endowed the composite with the high strength while the compliance of the elastomer matrix provided the high extensibility. Having a similar mechanism as DN gels, the composite was found to be significantly tougher than either of the constituents. The nonlinear behavior in the composite separated it into two coexisting phases - a softer phase with separated magnet links and a stiffer phase with connected magnet links - which led to the stress plateau on the tensile curve. Further stretching was manifested by the growth of the disconnected softer phase at the expense of the linked stiffer phase, until all magnets were separated. The unloading curves appeared drastically different from the loading curves, as the force needed to separate two magnets was much higher than the force at which two separated magnets snapped back. Such asymmetry between loading and unloading was the main cause of the hysteresis in the stress-strain curve and the energy dissipation. To further understand the physical mechanism and the damage process of the magnetic DN composite, a simple model was developed to examine the deformation and damage dissipation process of composite. With very few parameters, the model predictions agree qualitatively with the measured properties of the material, and the difference can be further reduced by accounting for the interfacial friction/adhesion, a second means of energy dissipation. With a combination of desired properties including high stretchability, self-healing, and high toughness, the magnetic DN composite is a viable candidate for various applications
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