1,721,078 research outputs found

    Episode 5: Dr. Arjun Srinivasan

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    Runtime 23:58Listen to Dr. Arjun Srinivasan discuss his work on improving antibiotic prescribing practices through surveillance of antibiotic use.Peterson, Marnie; Srinivasan, Arjun. (2016). Episode 5: Dr. Arjun Srinivasan. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/217978

    Mechanics of Biological Systems and Materials, Volume 6

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    Microneedles provide a minimally invasive means of delivering drugs into the body via the skin. The challenge to effective microneedle penetration is to bypass the inherent elasticity of the stratum corneum, the skin’s uppermost layer. However, there are few studies in the literature which focus on optimising parameters for repeatable penetration into skin. Here, a dropped weight impact testing rig was developed to allow high-density polymethylmethacrylate (PMMA) microneedles to be applied on to neonatal porcine skin at various velocities and forces. Methylene blue and histological staining were used to determine penetration effectiveness. Whilst methylene blue staining confirmed successful penetration of the stratum corneum, subsequent histological imaging demonstrated how deeply the microneedles had breached the layers of skin. The optimal parameters of velocity and force for eproducible and predictable penetration of the skin were found to be 4.52–4.8 m/s (nominal velocity of 3 m/s) and 3.35–4.17 N

    Jt Comm J Qual Patient Saf

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    CC999999/Intramural CDC HHSUnited States

    J Infect Dis

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    Public health offers infectious disease physicians a variety of rewarding career options. Our training and skills make us well suited to a variety of roles in public health. This article summarizes some of the options for careers in public health and describes why ID physicians are so well suited to them.CC999999/Intramural CDC HHS/United State

    Cleve Clin J Med

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    Improving our antibiotic use is critical to the safety of our patients and the future of medicine. This can improve patient outcomes, save money, reduce resistance, and help prevent negative consequences such as Clostridium difficile infection. The US Centers for Disease Control and Prevention (CDC) is undertaking a nationwide effort to appropriately improve antibiotic use in inpatient and outpatient settings.CC999999/Intramural CDC HHSUnited States

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Discourse lines:visualising current policy and media storylines of opportunity and disadvantage with narrative exploration maps

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    Topics of disadvantage are often discussed in the media. The discourseof disadvantage is multidimensional and has many intersectingelements, with some issues more common than others (e.g. violence,addiction), and some tending to co-occur, like human rights,criminal justice, and health to name just a few common themes.Here, we introduce and describe “Discourse Lines”, an online interactivevisualisation to discover which co-occurring disadvantageissues are being discussed in the media, and which ones are left out and obscured. The visualisation presents an AI-assisted analysis ofnews articles on topics of discourse. Our multi-scale architecturemetro map visualisation invites users to drill down from a topicsoverview landing map to topic-specific metro maps until individualnews articles. This dynamic platform allows users to see how discourseon topics of disadvantage unfolds and how news conflates orseparates various issues over time

    Discourse lines:visualising current policy and media storylines of opportunity and disadvantage with narrative exploration maps

    No full text
    Topics of disadvantage are often discussed in the media. The discourseof disadvantage is multidimensional and has many intersectingelements, with some issues more common than others (e.g. violence,addiction), and some tending to co-occur, like human rights,criminal justice, and health to name just a few common themes.Here, we introduce and describe “Discourse Lines”, an online interactivevisualisation to discover which co-occurring disadvantageissues are being discussed in the media, and which ones are left out and obscured. The visualisation presents an AI-assisted analysis ofnews articles on topics of discourse. Our multi-scale architecturemetro map visualisation invites users to drill down from a topicsoverview landing map to topic-specific metro maps until individualnews articles. This dynamic platform allows users to see how discourseon topics of disadvantage unfolds and how news conflates orseparates various issues over time

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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