1,720,964 research outputs found
Correction: Use of the non-paretic arm reflects a habitual behaviour in chronic stroke
No full textCorrection to: Journal of NeuroEngineering and Rehabilitation (2025) 22:135 h t t p s : / / d o i. o r g / 1 0. 1 1 8 6 / s 1 2 9 8 4-0 2 5-0 1 6 6 1-5 In the sentence beginning 'Our results demonstrate that not using the ... in demanding (e.g. time-limited) situations. ' in the Conclusions heading under the Abstract section of this article [1], The word "not" needs to be deleted from the sentence. The corrected sentence is 'Our results demonstrate that using the non-paretic arm may reflect a habit response that is more readily triggered in demanding (e.g. time-limited) situations. ' The original article has been corrected. References 1. Sporn S, Bonyadi E, Fathana R, et al. Use of the non-paretic arm reflects a habitual behaviour in chronic stroke. J Neuroeng Rehabil. 2025;22:135. h t t p s : / / d o i. o r g / 1 0. 1 1 8 6 / s 1 2 9 8 4-0 2 5-0 1 6 6 1-5
High-dose high-intensity Queen Square upper-limb rehabilitation for people with chronic stroke (INTENSIVE): protocol for a single-centre, randomised controlled trial
No full textIntroduction There is currently insufficient high-quality evidence to make general recommendations about high-dose high-intensity upper-limb rehabilitation programmes. Here we describe a randomised controlled trial that will determine the efficacy of two forms of high-dose, high-intensity upper-limb rehabilitation provided in a rehabilitation unit setting.Methods and analysis Patients with moderate upper-limb impairment (n=105, at least 6 months after stroke) will be randomised to either (1) high-dose high-intensity conventional upper-limb rehabilitation, (2) high-dose high-intensity virtual reality-based upper-limb rehabilitation and (3) usual care (a waiting list control group). Groups 1 and 2 will receive a minimum of 45 hours of active time on task over 3 weeks. Outcome measures will be collected at (T1) baseline; (T2) immediately post intervention and (T3) 3 months after the intervention has finished. The primary outcome measure will be the Fugl-Meyer Upper Extremity Assessment at 3 months after the intervention. Secondary outcome measures will be clinical, kinematic and neurophysiological using transcranial magnetic stimulation and electroencephalography. Explanatory measures will include MRI-based markers for integrity of the corticospinal tract, dorsal column-medial lemniscal pathway, grey and white matter and lesion load. The aim is to detect a difference of 7.25 points on the Fugl-Meyer Upper Extremity Assessment between each treatment group and the waitlist control group, with a power of 0.9 and significance of 0.025 (to account for two primary analyses). Analysis of change in the primary and secondary outcome measures will be performed using mulitple regression analysis.Ethics and dissemination The study protocol (V.1) has been approved by the Wales Research Ethics Committee 2 Cardiff (Rec reference: 22/WA/0065) on 15 March 2022. All recruited participants will provide informed consent. Trial results will be disseminated through peer-reviewed publications, presentations at major stroke/neurorehabilitation conferences and outreach to relevant stakeholder communities.Trial registration number NCT05527262.This study is sponsored by the Joint Research Office at University College London: Mr Pushpsen Joshi. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article. This research was funded by the Stroke Association grant (Dr LTT- SA PDF 20\100007). The views expressed are those of the author(s) and not necessarily those of the funder. This research is also funded by the Jon Moulton Charity Trust
Data repository - behavioral, electrophysiological
No full textData from Sporn, Sebastian, Thomas Hein, and Maria Herrojo Ruiz. "Alterations in the amplitude and burst distribution of sensorimotor beta oscillations impair reward-dependent motor learning in anxiety." bioRxiv (2019): 442772
Data repository - behavioral, electrophysiological
No full textData from Sporn, Sebastian, Thomas Hein, and Maria Herrojo Ruiz. "Alterations in the amplitude and burst distribution of sensorimotor beta oscillations impair reward-dependent motor learning in anxiety." bioRxiv (2019): 442772
Data repository - behavioral, electrophysiological
No full textData from Sporn, Sebastian, Thomas Hein, and Maria Herrojo Ruiz. "Alterations in the amplitude and burst distribution of sensorimotor beta oscillations impair reward-dependent motor learning in anxiety." bioRxiv (2019): 442772
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Modulation of Motor Vigor by Expectation of Reward Probability Trial-by-Trial Is Preserved in Healthy Ageing and Parkinson's Disease Patients
Get PDFMotor improvements, such as faster movement times or increased velocity, have been associated with reward magnitude in determin-istic contexts. Yet whether individual inferences on reward probability influence motor vigor dynamically remains undetermined. We investigated how dynamically inferring volatile action-reward contingencies modulated motor performance trial-by-trial. We conducted three studies that coupled a reversal learning paradigm with a motor sequence task and used a validated hierarchical Bayesian model to fit trial-by-trial data. In Study 1, we tested healthy younger [HYA; 37 (24 females)] and older adults [HOA; 37 (17 females)], and medicated Parkinson's disease (PD) patients [20 (7 females)]. We showed that stronger predictions about the tendency of the action -reward contingency led to faster performance tempo, commensurate with movement time, on a trial-by-trial basis without robustly modulating reaction time (RT). Using Bayesian linear mixed models, we demonstrated a similar invigoration effect on performance tempo in HYA, HOA, and PD, despite HOA and PD being slower than HYA. In Study 2 [HYA, 39 (29 females)], we additionally showed that retrospective subjective inference about credit assignment did not contribute to differences in motor vigor effects. Last, Study 3 [HYA, 33 (27 females)] revealed that explicit beliefs about the reward tendency (confidence ratings) modulated performance tempo trial-by-trial. Our study is the first to reveal that the dynamic updating of beliefs about volatile action-reward contingencies positively biases motor performance through faster tempo. We also provide robust evidence for a preserved sensitivity of motor vigor to inferences about the action-reward mapping in aging and medicated PD
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