1,721,011 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Advantages of robotic right colectomy over laparoscopic right colectomy beyond the learning curve: a systematic review and meta-analysis
Background: With the widespread application of robotic systems and the increasing number of studies comparing robotic right colectomy (RRC) and laparoscopic right colectomy (LRC), there is a need for an up-to-date systemic review and meta-analysis assessing the advantages of this technique. Methods: The systemic review was performed in Medline, Scopus, Embase, Cochrane Oral Health Group Specialized Register and Google Scholar databases searching for studies comparing RRC and LRC, with no date restriction but limited to English and French literature. Two independent reviewers performed data extraction and qualitative synthesis. Random-effects models were used to summarize the risk ratio (RR) and mean differences (MD) with 95% confidence interval (CI). Results: Twenty-six non-randomized clinical trials (NRCTs) and 1 RCT were included. Overall, 2,314 patients underwent RRC and 17,791 LRC. Operative time was significantly longer for RRC with a MD of 45.36 min (95% CI: 31.75-58.97; P<0.00001). Conversion rate was significantly lower in the RRC group with a RR of 0.47 (95% CI: 0.27-0.81; P=0.007, I-2=33%). Also, the number of harvested lymph node was significantly higher in the RRC group than the LRC group, with a MD of 2.03 (95% CI: 0.45-3.61; P=0.01, I-2=68%). Estimated blood loss favored RRC, with a MD of-8.68 (95% CI:-17.27 to-0.08; P=0.05, I-2=46%). There was no difference in the overall complication rate, mortality, anastomotic leakage, and time to first flatus. However, a significantly shorter hospital stay was associated with RRC, with a MD of -0.60 (95% CI:-1.01 to-0.19; P=0.004, I-2=64%). No quantitative analysis could be performed for oncological outcomes. RRC was associated with significantly higher costs (MD 3,185.50 USD; 95% CI: 720.98-5650.02; P=0.01, I-2=94%). Conclusions: RRC is a safe procedure that may offer certain advantages over LRC as lower conversion rate, blood loss, hospital stay. However, this should be balanced out with increased operative time and higher costs
Vascular complications following liver transplantation: A literature review of advances in 2015
La souffrance hépatocytaire au cours des hépatectomies n'est pas liée au clampage pédiculaire.
Introduction
L'augmentation des transaminases après hépatectomie est considérée comme un marqueur fiable de la souffrance hépatocytaire et le clampage pédiculaire comme le principal responsable de cette souffrance. Plusieurs études n'ont cependant pas trouvé de corrélation stricte entre la cytolyse postopératoire et la durée du clampage. Nous avons donc étudié de façon prospective la cinétique des transaminases durant et après une hépatectomie majeure.
Matériels et Méthodes
Entre Juin 2003 et Avril 2004, 52 patients, âgés de 53 ± 14 ans, ayant eu une hépatectomie droite élective et sans geste associé, ont été inclus dans cette étude. Deux des auteurs (VT et AB) ont réalisé des prélèvements sanguins séquentiels pour dosage des transaminases (AST et ALT) avant l'incision, avant la section parenchymateuse, avant la fermeture, puis à J1, 2, 5 et 7 postopératoires. L'hépatectomie a été réalisée sous clampage intermittent (15 à 64 minutes, moyenne 37) chez 42 patients et sans clampage chez 10 patients. Ces deux groupes de patients étaient comparables.
Résultats
Les concentrations d'AST et d'ALT étaient respectivement de 28 ± 8 et 30 ± 10 avant l'incision, de 152 ± 83 et 144 ± 116 avant la section parenchymateuse et de 304 ± 186 et 273 ± 187 avant la fermeture. Les concentrations avant la fermeture étaient comparables chez les patients ayant ou n'ayant pas eu de clampage pédiculaire (AST : 308 ± 194 vs 290 ± 156 et ALT : 273 ± 187 vs 275 ± 198). Les concentrations postopératoires de transaminases étaient également comparables chez les patients ayant ou n'ayant pas eu de clampage (AST J1 302 ± 118 vs 303 ± 133, J2 165 ± 70 vs 181 ± 85, J5 74 ± 32 vs 76 ± 43, J7 57 ± 18 vs 55 ± 17 ; ALT J1 326 ± 148 vs 286 ± 100, J2 258 ± 148 vs 215 ± 69, J5 135 ± 59 vs 114 ± 53, J7 83 ± 43 vs 84 ± 30).
Conclusion
Au cours des hépatectomies, les transaminases augmentent précocement, avant la section parenchymateuse et leur cinétique postopératoire n'est pas influencée par le clampage pédiculaire. Ces résultats suggèrent que la souffrance hépatocytaire, au cours des hépatectomies, peut avoir d'autres causes que l'ischémie reperfusion
Post-operative serum transaminase levels (TRL) is more related to the weight of resected liver rather than the injury of the remnant liver
Background. Post-operative increase of transaminase levels (TRL) is usually used as the main marker of hepatocyte injury of remnant liver after hepatectomy with vascular clamping.
Aims. In this prospective study we evaluated the level of transaminase during the peri-operative period of liver resection procedure in patients with and without vascular clamping according to the resected liver volume.
Methods. Between June and November 2005, fifty patients, aged 53±13 years, who underwent hepatectomy on normal liver were included in a prospective study. Major resection (>3 segments) was realised in 40 (80%) patients. Liver transection was performed in 25 (50%) patients under intermittent clamping for a mean duration of 38 min (range 15–64 min). All patients underwent serial blood samples assessing transaminase levels (ALT) during surgical procedure, respectively before incision, before liver transection and before abdominal closure and post-operatively, respectively on days 1, 2, 5 and 7.
Results. As shows in the table TRL which increase early, at the end of resection, remain stable on postoperative day (POD) 1, decrease thereafter and was not affected by the presence of clamping. Major hepatectomy had significant higher TRL than minor hepatectomy at the end (342±216 vs 219±102) and on day 1 (364±204 vs 231±160). TRL at the end of surgery and on POD 1 has a significant correlation with the weight of resected liver according to Sperman/rho.
Conclusions. Our results suggest that the early TRL should be considered as reflect of the damaged resected liver rather than the damage of remnant liver
INTRA-OPERATIVE LIVER INJURY IS NOT ONLY RELATED TO VASCULAR CLAMPING
INTRODUCTION AND AIM: It is widely accepted that during liver resections parenchymal ischemia is induced by vascular clamping and assessed on days 1 and 2 by the postoperative increase of serum transaminase level (ALT). This prospective study aimed to identify early changes in ALT level during resection. PATIENTS AND METHODS: From June 2003, 52 patients (aged 53±14 years) with an elective right hepatectomy, including 42 with intermittent clamping for a mean duration of 37 min (range 15–64), were included. Blood samples were collected during operation (before incision, before liver transection and before abdominal closure) and postoperatively, on days 1, 2, 5 and 7. RESULTS: During operation mean ALT level was 30±10 before incision; 144±116 before transection and 273±187 before abdominal closure. ALT level before abdominal closure was not statistically different in the groups with or without clamping (273±187 vs 275±198). Postoperative mean ALT level was 318±140 on day 1 and 249±137 on day 2 without significant difference according to the presence or not of clamping (326±148 vs 286±100 on day 1 and 258±148 vs 215±69). The mean ALT level before abdominal closure reflected the mean ALT level on day 1 (273±187 vs 318±140). CONCLUSION: During liver resection, the ALT level started to increase early, before parenchymal transection and was not affected by the presence of clamping. The peak of ALT level, which can be anticipated at the end of the procedure, seems to be related to factors other than ischemia-reperfusion injury
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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