547 research outputs found
A stitch in time: preserving peace on Bougainville
No full textA decade after the successful peacekeeping mission, and a year and a half before the window opens for a referendum on Bougainville’s political status, the peace process is dangerously adrift.In this paper, Peter Jennings and Karl Claxton set out a plan to help deliver a sustainable solution for next steps in the peace process. An Australian-led preventive development effort, conducted in close cooperation with our regional partners, is needed to avoid the future requirement for a larger, costlier, riskier, and more intrusive peacekeeping mission than the limited intervention appropriate in 1997-2003.The new Government’s decision to link aid more directly to our strategic interests could assist. While the initiative would require a significant initial investment, it could create a substantial longer-term cost saving and avoid serious military, diplomatic and reputational risks
"Infrastructure Investment for Tomorrow, A Financing Plan to Eliminate the Deferred Maintenance on the Nation's Roads"
No full textRegan presents a long-term public investment proposal to preserve and upgrade the nation's infrastructure system. He offers a unique financing plan to eliminate much of the backlog of deferred maintenance that plagues America's roads and bridges. The plan would allow states and municipalities to get out from under this burden with a one-time upgrading program and then attain a new capacity to maintain and improve their infrastructure networks. Regan concludes that the goal of long-term investing is "to make possible sustained growth, improved productivity, and a strengthened private sector" for the next generation. A program to upgrade the nation's infrastructure base could help the United States achieve this goal.
Approach to headaches in children
No full textCITATION: Solomons, R., Schoeman, J. & Van Toorn, R. 2011. Approach to headaches in children. Continuing Medical Education, 29(4):171-174.The original publication is available at http://www.cmej.org.zaHeadache is a common problem in childhood
– up to 25% of schoolchildren suffer from
chronic, recurrent headaches. Although
primary headaches are far more common
than those with a secondary cause, it is the
latter that result in the most anxiety for
families.1 A logical approach to investigating
and managing headaches is needed.http://www.cmej.org.za/index.php/cmej/article/view/2162Publisher's versio
Blonde Builds Suburbia: Ouida Baggett Regan and the Alternate Construction of Femininity
No full textOuida Baggett Regan (1927-2017) was a developer, from Pensacola, FL in the mid-twentieth century.
• A white woman's place was as a homemaker and mother; yet she built thousands of homes and the tallest building in the FL panhandle.
• How did she navigate gender norms, as a divorcee mother and self-made millionaire?
• Regan strategically deployed gendered tropes, at times emphasizing her domesticity and femininity, and others the bootstrap, masculine approach to a traditionally male field
Trading Justice for Peace? Reframing reconciliation in TRC processes in South Africa, Canada and Nordic countries
No full textConflict in its various manifestations continues to be a defining feature in many places throughout the world. In an attempt to address such conflict, various forms of a Truth and Reconciliation Commission (TRC) have been introduced to facilitate the transition from social conflict to a new dispensation. The introduction and subsequent proceedings of TRCs in South Africa, Canada and Norway are widely regarded as good examples of this approach. Against this background, a number of researchers from VID Specialized University and the University of the Western Cape had an exploratory meeting in Oslo in 2018 where the possibility for a joint research project under the broad theme of ‘discourses on reconciliation’ was first discussed. This led to two further research symposia in Cape Town and Tromsø in 2019. With the inclusion of specialists working on the Canadian Truth and Reconciliation process, these meetings demonstrated common ground and a shared understanding of the issues at stake. Moreover, it pointed to the differences between the South African, Canadian and Norwegian Commissions. In comparing the South African, Canadian and Norwegian experiences, researchers identified that these countries were, in fact, at different stages of their respective truth and reconciliation processes. This has prompted scholars to revisit and problematise these processes in relation to ongoing societal challenges. In all cases, it is quite apparent that reconciliation between individuals and groups remains a significant challenge
The neural instantiation of spontaneous counterfactual thought
No full textDec 2023 Revision:
This revision contains the scripts for the revised behavioral analyses, the script for the parametric modulation neuroimaging analysis (and relevant timing and behavioral files), and the parametric modulation significance testing. The neuroimaging data is available by contacting the author.
Original Submission:
This dataset contains the script and clean data for running the analyses on the relationship between the behavioral results and the within ROI multi-variate results in R. It also contains the scripts for running the single subject and group level neuroimaging analyses in AFNI, MATLAB, and R, as well as the scripts for running the experimental paradigm in MATLAB.
Additional data and scripts are available by request
Trading Justice for Peace? Reframing reconciliation in TRC processes in South Africa, Canada and Nordic countries
No full textConflict in its various manifestations continues to be a defining feature in many places throughout the world. In an attempt to address such conflict, various forms of a Truth and Reconciliation Commission (TRC) have been introduced to facilitate the transition from social conflict to a new dispensation. The introduction and subsequent proceedings of TRCs in South Africa, Canada and Norway are widely regarded as good examples of this approach. Against this background, a number of researchers from VID Specialized University and the University of the Western Cape had an exploratory meeting in Oslo in 2018 where the possibility for a joint research project under the broad theme of ‘discourses on reconciliation’ was first discussed. This led to two further research symposia in Cape Town and Tromsø in 2019. With the inclusion of specialists working on the Canadian Truth and Reconciliation process, these meetings demonstrated common ground and a shared understanding of the issues at stake. Moreover, it pointed to the differences between the South African, Canadian and Norwegian Commissions. In comparing the South African, Canadian and Norwegian experiences, researchers identified that these countries were, in fact, at different stages of their respective truth and reconciliation processes. This has prompted scholars to revisit and problematise these processes in relation to ongoing societal challenges. In all cases, it is quite apparent that reconciliation between individuals and groups remains a significant challenge
The bookseller and the basketball player: tales from the French Polonia
No full textAuthor has checked copyrightAD 09/01/201
Improving early diagnosis of tuberculous meningitis in children
No full textTutu-Furth, A.M. van [Promotor]Schoeman, J.F. [Copromotor
Utility of genetic testing in children with developmental and epileptic encephalopathy (DEE) at a tertiary hospital in South Africa: A prospective study
No full textThesis (MMed) -- Stellenbosch University, 2021.ENGLISH ABSTRACT: Introduction: The developmental and epileptic encephalopathies (DEE) are a heterogeneous group of rare neurodevelopmental disorders, characterised by early-onset seizures that are often intractable, electroencephalographic abnormalities, and developmental delay or regression. Studies have shown that 70% of epilepsy cases have a genetic basis. Next-generation sequencing (NGS) technologies have led to the identification of several epilepsy-related genes, including those responsible for DEE. The reported diagnostic yield of an NGS-based testing for patients with epilepsy ranges from 10 to 40%, depending on the test and the phenotypes among the studied cohorts. Objectives: The aim of this study was to evaluate the diagnostic yield of NGS-based epilepsy gene panel in children with DEE and to assess the value of the genetic results to the parents and managing physicians. Design: A prospective cohort study of 41 consecutive children diagnosed with DEE (onset before 3 years of age) was recruited over a 2-year period (2019-2021). Pre- and post-test genetic counselling were offered to all study participants. The results were classified into three categories: positive (pathogenic/likely pathogenic), inconclusive (variant of unknown significance), or negative. After the results were obtained, questionnaires were administered to both the physicians and the parents. Result interpretation and careful matching of the variant to the clinical phenotype was carried out with the help of a medical geneticist. Results: We found a positive genetic diagnosis in 20 of 41 (48%) children. Variants in SCN1A (n=5), KANSL1 (n=2), KCNQ2 (n=2) and CDKL5 (n=2) accounted for the greatest number of positive findings. Rarer genetic findings included IQSEC2, KCNMA1, SMC1A and STXBP. All except 1 of the pathogenic variants identified fully explained and matched the respective phenotypic description in the patient at time of diagnosis. Gene-specific treatment changes were initiated in 26% patients following the genetic diagnosis. Both parents and physicians expressed usefulness of genetic testing in patients with DEE. Conclusion: With this study, we show that an NGS gene panel is highly effective in diagnosing South African children with DDE. The study diagnostic yield (48%) is similar to previously reported paediatric cohorts, and the genetic findings proved useful for therapeutic decision making and genetic counseling. Although the diagnostic yield in this study was high, therapeutic consequences and ultimate improvement of the patient's clinical state were still limited."Geen opsomming beskikbaar."Master
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