188,425 research outputs found
Podziemne składowanie solanki z przetwórstwa potasu: studium możliwości
No full textApproaches and requirements concerning geological investigation of potash deposits for substantiation of a possibility of underground disposal of excess potash processing brines are discussed. The main stages of geological investigation are defined, and a complex of studies to be carried out at the first stage is considered in details. Mathematical modelling of the injection of excess brines has been carried out. Potential intake capacity of collector-beds has been evaluated, and necessary amount of injection wells has been justified.W artykule przedyskutowano możliwości podziemnego składowania solanki z przetwórstwa potasu. Zdefiniowano główne stadia poszukiwań geologicznych i złożoność rozpoznania. Przeprowadzono matematyczne modelowanie wtłaczania solanki oraz przeanalizowano potencjalną pojemność warstw przeznaczonych do magazynowania
Nanotechnology-based approaches for regenerative medicine and biosensing
No full textThe recent emergence of nanotechnology has set high expectations in many fields of science, especially in biology and medicine. Nanotechnology-based approaches are expected to solve key questions in the emerging field of regenerative medicine. Regenerative medicine essentially deals with regeneration of cells, ultimately leading to the formation of tissues and organs. For this purpose, stem cells, embryonic stem cells or adult stem cells, are thought to be ideal resources. However, many challenges need to be addressed before the full therapeutic potential of stem cells can be harnessed. Controlling the differentiation of stem cells into cells of a specific lineage is extremely vital and challenging. Addressing this challenge, in this work, novel nanotechnology-based approaches for controlling the differentiation of neural stem cells (NSCs) into neurons has been presented. Regeneration of damaged neurons, due to traumatic injuries or degenerative diseases, is extremely challenging. For this purpose, NSCs can be used as resources that can differentiate into neurons, thus having great potential in solving needs of many patients suffering from such conditions. For controlling the differentiation of stem cells, soluble cues (comprising of small molecules and biomolecules) and insoluble cues (cell-cell interactions and cell-microenvironment interactions) play a very important role. The delivery of soluble cues, such as genetic material, into stem cells is extremely challenging. The initial part of this work presents the use of nanomaterials for efficiently delivering soluble cues such as small molecules and small interfering RNA (siRNA) into NSCs for controlling their differentiation into neurons. However, for regenerative purposes, it is preferred that least amounts of the delivery vehicle be used. Thus, the following part of the thesis presents the development and applications of nanotechnology-based approaches for enhancing the differentiation of NSCs into neurons using insoluble cues. The cellular microenviroment, consisting for the extracellular matrix (ECM) was modified by the use of nanostructures, to deliver siRNA into NSCs to enhance neuronal differentiation. Nanotopography-mediated reverse uptake of only the siRNA molecules from the ECM was achieved by the NSCs. NSC differentiation was also controlled by the use of protein micropatterns, wherein the pattern geometry and size defined the fate of the NSCs. Lastly, graphene, in combination with nanoparticles was used as component of the ECM to not only enhance the differentiation of NSCs into neurons, but also align the axons of the differentiated NSCs, having significant implications for its use in regenerating injured spinal cords. The final portion of the thesis presents the applications of nanotechnology for developing highly sensitive and selective biosensors, for detecting biomarkers implicated in various diseases such as cancer and acute pancreatitis.Ph. D.Includes bibliographical referencesby Aniruddh P. Solank
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Material Designers. Boosting talent towards circular economies
No full textThis book provides a better understanding on how materials design can contribute to attain a more circular economy. It contains a compilation of expert articles and short interviews, a glossary of concepts, original resources, detailed finalists and winners’ projects and the full directory of material designers
Synoptic maps from two viewpoints
No full textContext. Over recent decades, various kinds of magnetic synoptic chart products have seen major improvements in observation cadence, resolution, and processing, but their creation is still limited by the 27.27 day rotation rate of the solar surface.
Aims. Co-observation from a second vantage point away from the Earth–Sun line with SO/PHI enables the creation of combined magnetic synoptic maps from observation periods that are significantly shorter than a typical Carrington rotation, and therefore provides a data product with magnetic information that is temporally more consistent.
Methods. We upgraded the SDO/HMI synoptic map pipeline in order for it to be compatible with SO/PHI observations at variable distances and a much lower and variable observation cadence. This enabled us to produce combined magnetic synoptic maps using SO/PHI data taken from the far side of the Sun.
Results. We present a pipeline to produce combined magnetic synoptic maps from simultaneous SO/PHI and SDO/HMI observations. Depending on the orbital position of SO/PHI, our combined synoptic maps can be produced up to 13 days faster than any other comparable data product currently available. This strongly reduces the time-lag between the observations that are used to build the map and thereby provides a more consistent map of the magnetic field across the solar surface
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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