74 research outputs found
Local well-posedness and wave breaking results for periodic solutions of a shallow water equation for waves of moderate amplitude
No full textDuruk Mutlubas, Nilay/0000-0003-1160-9236We study the local well-posedness of a periodic nonlinear equation for surface waves of moderate amplitude in shallow water. We use an approach proposed by Kato which is based on semigroup theory for quasi-linear equations. We also show that singularities for the model equation can occur only in the form of wave breaking, in particular surging breakers. (C) 2013 Elsevier Ltd. All rights reserved.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)The author is grateful to Vienna University for their hospitality and to The Scientific and Technological Research Council of Turkey (TUBITAK) for their support
Evliyâ Çelebi‟nin seyahatnâme'sinde görsel sanat eserlerinin tasviri: ekfrastik bir yaklaşım
No full textCataloged from PDF version of article.Includes bibliographical references (leaves 246-257).As a part of the ancient Greek and Roman rhetorical practices, ekphrasis
basically means the verbalisation of a visual object, and it has become a literary tool
in time. Since the description of Achilles‘ shield in Homer‘s İlliad, ekphrasis has
been a frequently used literary practice which writers, historians, art critics apply.
Ekphrasis can be applied as the description of visual art objects through the fictional
forms such as poetry and novel as well as it occurs in the prose concerning history,
art criticism and travelogues; it is studied in order to analyse writer's handling with
the description of the object. Ekphrasis studies enable to capture the writer's
relationship between objectivity and subjectivity, the elements of his/her expressed
subjectivity, through literary tools. This study will examine Evliyâ Çelebi's
"ekphrastic" approach in describing mosques, churches and monasteries, paintings
and sculptures in Seyahatnâme (The Book of Travels), especially focusing on how
the subjective factors determining the writer‘s aesthetic appreciation occur in his
literary practice. What kind of a fictive language does ekphrasis, which is essentially
the act of making the silent image talk, show in Evliyâ Çelebi's representation? What
are the characters of the new images created by this language, which is independent
from the original objects, in other sense the images which Evliyâ created on his own
way? How does the reflection of personal taste and cultural positioning affect
aesthetic view of Evliyâ Çelebi‘s "ekphrastic" narrative? This questioning aims to
observe how the aesthetic view of Seyahatnâme's author takes shape and to be a
model of an approach to put forth the new literary qualities of Seyahatnâme's in the
light of ekphrasis study. The problem of "ekphrasis" enables Seyahatnâme which has
been already a study topic for various social sciences, to be evaluated in the
discipline of fiction more widely. As the issue concerns basically the relationship
between visuality and writing, it would bring a new interdisciplinary approach to
Seyahatnâme studies.by Nilay Kaya
DRUG UTILIZATION PATTERN AND PHARMACOECONOMIC ANALYSIS OF ANTIHYPERTENSIVE DRUGS PRESCRIBED IN SECONDARY CARE HOSPITAL IN GUJARAT, INDIA
No full textABSTRACTObjective: Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if notdetected early and treated appropriately. A large number of antihypertensive drugs alone or in various combinations are available, and physiciansneed to choose most appropriate drug for a particular patient. Pharmacoeconomic and drug utilization studies at regular intervals help physicians toprescribed rational drugs with high efficacy along with minimal cost.Methods: The prospective observational study was conducted at Seth H. J. Mahagujarat Hospital from July to December 2013. 250 hypertensivepatients, attending medicine outpatient department were included for drug utilization study and 100 hypertensive patients, attending in patientsdepartment were included for pharmacoeconomics analysis during the study period.Result: The most frequently prescribed antihypertensive drug as monotherapy, as combination therapy and in fixed dose combinations was calciumchannel blocker (Amlodipine). Generic drugs showed same efficacy as brand drug, but both drugs were significantly differed in the prize. Among 100inpatients admitted for the hypertensive condition in general ward total of direct medical cost was 65.19% and total of indirect medical cost was34.81%. β-blocker and diuretics were the most effective therapy which is followed by the clonidine, envas (Enalapril), and then, amlodipine.Conclusion: We concluded from this study that use of β-blockers and diuretics were most cost-effective for the hypertensive patients in this study.Keywords: Antihypertensive drugs, Drug utilization study, Pharmacoeconomics analysis. </jats:p
DRUG UTILIZATION PATTERN AND PHARMACOECONOMIC ANALYSIS OF ANTIHYPERTENSIVE DRUGS PRESCRIBED IN SECONDARY CARE HOSPITAL IN GUJARAT, INDIA
No full textABSTRACTObjective: Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if notdetected early and treated appropriately. A large number of antihypertensive drugs alone or in various combinations are available, and physiciansneed to choose most appropriate drug for a particular patient. Pharmacoeconomic and drug utilization studies at regular intervals help physicians toprescribed rational drugs with high efficacy along with minimal cost.Methods: The prospective observational study was conducted at Seth H. J. Mahagujarat Hospital from July to December 2013. 250 hypertensivepatients, attending medicine outpatient department were included for drug utilization study and 100 hypertensive patients, attending in patientsdepartment were included for pharmacoeconomics analysis during the study period.Result: The most frequently prescribed antihypertensive drug as monotherapy, as combination therapy and in fixed dose combinations was calciumchannel blocker (Amlodipine). Generic drugs showed same efficacy as brand drug, but both drugs were significantly differed in the prize. Among 100inpatients admitted for the hypertensive condition in general ward total of direct medical cost was 65.19% and total of indirect medical cost was34.81%. β-blocker and diuretics were the most effective therapy which is followed by the clonidine, envas (Enalapril), and then, amlodipine.Conclusion: We concluded from this study that use of β-blockers and diuretics were most cost-effective for the hypertensive patients in this study.Keywords: Antihypertensive drugs, Drug utilization study, Pharmacoeconomics analysis.Â
Root cause analysis of medication errors at a multi-specialty hospital in Western India
No full textBackground: Medication use is a complex process in a medical setting, it starts with physician prescribing, followed by nurse transcribing, pharmacist dispensing, medication administration, and patient monitoring. There is a definite role of clinical pharmacists in reduction of Medication errors by examining and evaluating its causes and communicate the results to physicians and caregivers. The aim of the present study was study of medication errors for the safety & the health benefit of the patient visiting multi specialty hospital. Methods: The Observational study was carried out at in-patient appointments at multi specialty hospital during the period of June 2012 to April 2013 at Baroda. Results: Total of 300 patients were observed out of which medication error has occurred in 117 (39%) cases considering 62% were males & 38% female patients. Out of 117 cases 28% of transcription errors, 62% of prescription errors, 11% of dispensing errors & 16 % Administration errors. 51% of medication errors were occurring in the age group of 40-60. Root cause analysis showed that prescription error was due to Illegible handwriting, No dosage form prescribed, the Wrong Brand name prescribed; transcription error due to Wrong drug is transcribed; administrative error due to Wrong dose is administered, Drug administered through wrong route, Wrong drug is administered while dispensing error due to Urgent dispensation not done within 10 to 15 minutes, Wrong dose dispensed.Conclusion: Most common medication errors were Prescription error & Transcription error which accounts for almost 77% of the total error, which is according to Pareto 80:20 Principle
Halk kütüphaneleri: Araştırmalar ve Görüşler
No full textThis book which is a compilation of previously published (1989-2013) articles, personal opinions, observations and translations of the author underlines the significance of public libraries. While some of the articles belong to the author himself, the rest are joint works. As public libraries are discussed in all its parts, this book is believed to be an easy accessible and well-coordinated source for researchers
Multiplayer game frameworks for crowd-aware co-design of environment
No full textThis paper proposes two frameworks in the field of Games in Research. • Proposal1 Architectural design decisions stand to benefit by accounting for the presence and activities of human crowds that inhabit these spaces. Computational methods for simulating synthetic crowds provide a cost-effective means of exploring and analyzing the design search space. However, the crowd-aware architectural design is a complicated combinatorial decision process, where small changes in the design solution may affect crowds and their flow patterns in unexpected and potentially unintuitive ways. Existing solutions rely on expert intuition or automation, but are unable to account for much contradicting, and often subjective properties while optimizing designs. A single solution approach may also miss potential design solutions that achieve the desired objective specifications while meetingsubjectivecriteria. Weproposeameansofcombiningthesemethodsinagamified framework. Using our system, “players" (novice users or experts) can rapidly iterate on their designs while soliciting feedback from computer simulations of crowd movement, as well as the designs of previous players. Our approach affords a new way of thinking of the solution space in that it inherently supports competitive co-design and crowdsourced solutions. We evaluate our framework through a user study and demonstrate the potential ii of crowd-aware co-design of environments using simulation guided multiplayer games. • Proposal2 Games in research is a modern trend in the world of research. Games are being used to simulate, monitor and test occurrences in reality. However, Game development knowledge is the initial requirement to use games in research either in any non-technical or technical field. Besides, availability of existing games suited to research is very meager. Also, attracting and reaching out to enough users for proper user study is a difficult task. We propose a connected real-time website and desktop-based game application. The website is themed as a social network which will help connect researchers with gamers and keep them updated. Our application also allows a researcher to choose and modify a few configuration parameters to change the game according to his requirement as well as dedicated ownership to the collected data. The game application provides a robust Massive Multiple Online game environment for a smooth and exciting gaming experience to involve gamers to contribute to research.M.S.Includes bibliographical referencesby Nilay Chakrabort
Why Are Students Not Engaging In Online Learning? A Lecturer’s Reflection
No full text
The poster is a reflective account of practice on the author’s experiences of student engagement within online learning during Semester One of the 2020/21 academic year (September to December 2020). This was the first semester many universities prepared for a fully online semester, as opposed to the quick transition to online teaching experienced in the first UK lockdown of March 2020.
The learning and teaching practices used this semester were based on practices developed for transactional distance. Despite these adoptions, the author experienced a lack of student engagement with online learning. Student engagement is viewed as an integral part of the learning process. Further, online learning is likely to remain a core component as universities move towards hybrid teaching and learning practices post-pandemic. Thus, a better understanding of student engagement in an online learning context is needed. This will enable universities to develop curriculum design and learning and teaching approaches better suited to online and hybrid learning.
Accordingly, the author reflected on the issues impacting upon student engagement and established three key problem areas, which were related to curriculum design and learning and teaching approaches. These problem areas will be examined in the poster and the author will offer recommendations to overcome these challenges.</p
ORAL BIOAVAILABILITY ENHANCEMEMENT OF BROMOCRYPTINE MESYLATE BY SELF-MICRO EMULSIFYING DRUG DELIVERY SYSTEM (SMEDDS)
No full textObjective: The purpose of this work was to enhance oral bioavailability of Bromocryptine Mesylate by preparing SMEDDS (self-micro emulsifying drug delivery system)Methods: Screening of oils, surfactants and co-surfactants were done by solubility study & pseudo ternary diagram. The batches of Bromocryptine Mesylate (BM)–SMEDDS were prepared and evaluated for droplet size analysis, poly dispensability index (PDI), robustness to dilution, zeta potential, in vitro dissolution. The optimized batch was compared with commercially available quick release tablets of BM (Brainstar®, 0.8 mg/tablet) by in vivo study (Pharmacodynamic study in rats).Results: Based on the drug\u27s solubility study, Akoline MCM, Tween80 and PEG400 were selected as oil, surfactant and co-surfactant, respectively. By pseudo ternary diagram, the components\u27 ratios were screened. In vitro drug release of the optimized batch was lower than the commercial preparation but in in vivo study, optimized batch was similar with commercial tablets.Conclusion: From the study, it was concluded that the group treated with optimized BM-SMEDDS showed better and sustained reduction in blood sugar as compared to control group and the group treated with marketed formulation, indicated improvement in bioavailability of drug. Keywords: Bromocryptine Mesylate, Type–II Diabetes, Self micro emulsifying drug delivery system, Bioavailability, Pharmacodynamic stud
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