305,159 research outputs found
Rectus sheath hematoma in an 80-year-old man with venous leg ulcer infection: a case report
No full textPatients with venous leg ulcers often present with comorbidities that increase the complexity of their care. In elderly patients, acute abdominal pain is frequently caused by intestinal occlusion, gastrointestinal tumors, and abdominal ischemia. We report the case of an 80-year-old man presenting with acute abdominal pain admitted to our unit because of venous leg ulcer infection
Diabetic foot in children and adolescents: The next epidemic? A meta-analysis
No full textAim. Recent estimates of the International Diabetes Federation indicate that 8.3% of adults - 382 million people - have diabetes mellitus (DM), one in two people with diabetes have no awareness of their own disease and the number of people with the DM is set to rise beyond 592 million in 2020. An increased prevalence of type 2 DM (T2DM) in children has been reported worldwide. Foot disorders result in major long-term complications for diabetic patients. Increased risks for lower limb amputation in adults have been associated with peripheral neuropathy with loss of protective sensation, peripheral vascular disease, altered biomechanics. There are few reports concerning foot problems in any pediatric cohort. The aim of this meta-analysis was to review the current literature on foot problems in children and adolescents with DM. Methods. A systematic review was performed on all articles published from January 1980 to August 2014 and listed in MEDLINE, EMBASE, CENTRAL, and in hand-searched reference lists from all identified articles. We searched the terms: "foot" AND "pediatric" AND "children" AND "diabetes mellitus". Results. The international guidelines recommend that children with diabetes have their feet examined since puberty and then at least annually for protective sensation, pulses, skin integrity, and treatable nail problems such as ingrown toenails. Some authors have reported that many young patients with DM have foot problems and evidence of early manifestation of peripheral neuropathy in adolescents with T2DM. Conclusion. By t this research we wanted to highlight the importance of foot examination and foot care advice for children and adolescents with diabetes. Larger prospective studies are required to establish prevalence and to optimize preventive interventions
Abnormal serum alanine aminotransferase levels are associated with impaired insulin sensitivity in young women with polycystic ovary syndrome.
No full textSFX(opens in a new window)|View at Publisher| Export | Download | Add to List | More... Journal of Endocrinological Investigation Volume 32, Issue 8, September 2009, Pages 695-700 Abnormal serum alanine aminotransferase levels are associated with impaired insulin sensitivity in young women with polycystic ovary syndrome (Article) Targher, G.a , Solagna, E.a, Tosi, F.a, Castello, R.a, Spiazzi, G.a, Zoppini, G.a, Muggeo, M.a, Day, C.P.b, Moghetti, P.a a Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Piazzale Stefani 1, 37126 Verona, Italy b Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom View references (31) Abstract Background and aim: Non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) are both associated with insulin resistance. We assessed whether NAFLD is associated with impaired insulin sensitivity in PCOS women independently of age and total adiposity. Subjects and methods: We enrolled 14 young PCOS women with NAFLD, 14 women with PCOS alone and 14 healthy controls, who were matched for age, body mass index, and total body fat (by bio-impedance analyzer). NAFLD was diagnosed by the surrogate measure of abnormal serum alanine aminotransferase (ALT) concentrations (defined as ALT>19 U/l) after excluding other secondary causes of liver disease (alcohol, virus, and medications). Insulin sensitivity was measured by euglycemic hyperinsulinemic clamp. Results: Insulin sensitivity was markedly decreased (p<0.001) in PCOS women with abnormal ALT levels, whereas it was similar between PCOS women with normal ALT levels and matched healthy controls (8.3±2.5 vs 12.1±1.7 vs 13.2±1.8 mg/min x kg of fat-free mass, respectively). PCOS women with abnormal ALT levels also had higher plasma triglycerides and lower HDL-cholesterol concentrations than those with PCOS alone. There was a strong inverse association between serum ALT levels and insulin sensitivity in the whole group of PCOS women (r=-0.59, p=0.0013). Conclusions: Abnormal serum ALT levels, as surrogate measure of NAFLD, are closely associated with impaired insulin sensitivity in young PCOS women in a manner that is independent from the contribution of age and total adiposity. Early recognition of NAFLD by radiological imaging tests in this group of young patients is warranted
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Author, publisher and bookseller : a tripartite synergy in Nigerian book industry
No full textThis work is about the roles of Author, Publisher and Bookseller in Book development in
Nigeria. The paper started by delving into the history of Book Publishing in Nigeria after
which it proceeded by defining who an author, a publisher, and a bookseller is and
expatiated on the indispensable roles of these key actors in Nigerian Book Industry and in
the emerging Information Society. Furthermore, the various constraints to book
development were identified while the paper advised on how the Book Industry can be
further promoted in Nigeria. However, the paper concluded and made recommendations
on how the Book sector can help in enhancing scholarship in the country
[Report to Chief J. E. Curry, by an unknown author #2]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
[Report to Chief J. E. Curry, by an unknown author #1]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
Mining e-mail content for author identification forensics
No full textWe describe an investigation into e-mail content mining for author identification, or authorship attribution, for the purpose of forensic investigation. We focus our discussion on the ability to discriminate between authors for the case of both aggregated e-mail topics as well as across different email topics. An extended set of e-mail document features including structural characteristics and linguistic patterns were derived and, together with a Support Vector Machine learning algorithm, were used for mining the e-mail content. Experiments using a number of e-mail documents generated by different authors on a set of topics gave promising results for both aggregated and multi-topic author categorisation
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