171,095 research outputs found

    Frederic A. Soderberg

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    Frederic A. Soderberg was born in Lowell, Massachusetts in September 1902. He graduated from Bangor High School and completed his degree as a Chemical Engineer in 1925 from the University of Maine. Soderberg started his professional career with International Paper Company where he worked from 1925-1928. He moved on to work with General Dyestuff Corporation, 1928-1959, becoming Manager of the Industrial Division in 1949. He joined F. C. Huyck & Sons in 1953 as Vice President of Marketing and became President of the corporation in 1959. Soderberg was a charter member of the University of Maine Pulp & Paper Foundation serving as Vice President from 1960-1961 and President from 1961 to 1967. He also served on the Foundation’s Board of Directors and received an honorary degree of Doctor of Science from the University. He was a member of the Commercial Development Association, the first Chair of the Chemical Marketing and Economic Division of the American Chemical Society, and Chair of the Paper Industry Management Association Affiliates. He also served as a delegate of the American Kennel Club. He died in Albany, New York on March 27, 1993.https://digitalcommons.library.umaine.edu/ppf_images/1004/thumbnail.jp

    Letter from Carl R. Soderberg to Henry O. George, March 18, 1960

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    Letter regarding a visit to the University

    Cytomegalovirus-induced autoimmunity

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    Human cytomegalovirus (HCMV) is a ubiquitous pathogen that causes severe infections in immunocompromised patients. During active infection, the virus is able to modulate the host immune system in immunocompetent as well as immunocompromised individuals. HCMV-infected patients often develop signs of immune dysfunction, such as autoimmune phenomena. Furthermore, case reports suggest a link between primary HCMV infection and onset of autoimmune disorders. Signs of active viral infection have also been identified in a number of autoimmune diseases, which further highlights the potential role of HCMV in the genesis and/or maintenance of immunopathological phenomena. Mechanisms by which HCMV could induce host immunopathology, inflammation and autoimmunity will be discussed as well as the opportunity to administer antivirals in selected patients

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Aluminide Coating Application for Protection of Anodic Current-Supplying Pins in Soderberg Electrolytic Сell for Aluminium Production

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    Anodic current-supplying pins (ACP) made of low-carbon steel corrode intensively due to the sulfur contamination of the carbon-based Soderberg anode and iron sulfides formation in the present aluminium production technology. The aluminide coatings produced by the liquid-phase method followed by the fluoride flux treatment of the steel samples were applied for the ACP protection. The protective layer based on α-Al2O3 and FeAl2O4 was formed on the steel surface in the course of the test run in the industrial Soderberg anode during the aluminium electrolysis. The aluminized ACP wear rates calculated by the linear extrapolation of data obtained during 150 days workout were 4.0 and 5.4 cm/year for the ACP with the aluminide coating and without it, respectively. The current load on the ACP remained almost the same for the aluminized and original uncoated samples with the exception of the initial “heating” period (400-600°C).</jats:p

    Mitomycin C in highly myopic eyes - Author reply

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    Ophthalmology. 2005 Feb;112(2):208-18; discussion 219. Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E. SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy. Abstract PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes. DESIGN: Prospective, double-masked, randomized clinical trial. PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia. METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months). MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH. RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively). CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK. Comment in Ophthalmology. 2006 Feb;113(2):357; author reply 357-8

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    The novel anti-rheumatic compound Rabeximod impairs differentiation and function of human pro-inflammatory dendritic cells and macrophages.

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    Rabeximod (9-chloro-2,3-dimethyl-6-(N,N-dimethylaminoethylamino-2-oxoethyl)-6H-indolo[2,3-b]quinoxaline) is a synthetic compound that is currently being developed for the treatment of rheumatoid arthritis (RA). Here, we investigated the effects of Rabeximod on the functionality of human antigen-presenting cells (APCs) of myeloid origin. Different subsets of professional APCs were generated from human monocytes in vitro and simultaneously treated with different doses of Rabeximod. Although Rabeximod had no effect on the differentiation of monocytes into anti-inflammatory macrophages (AI-Mφs), this compound impaired monocyte differentiation into monocyte-derived dendritic cells (MDCs) and pro-inflammatory allostimulated macrophages (Allo-Mφs). MDCs that were treated with Rabeximod resulted in a significant decrease in their ability to pinocytose antigens, while no effect was exerted by the drug on the ability of Allo-Mφs and AI-Mφs to phagocytose. Furthermore, we observed a significant reduction in the allostimulatory ability of MDCs and Allo-Mφs after treatment with Rabeximod, although this compound did not affect the low immunostimulatory capacity of AI-Mφs. Conversely, the effect of Rabeximod in influencing cytokine secretion by APCs appeared to be limited. In conclusion, Rabeximod impairs differentiation of monocytes into different pro-inflammatory APCs, leading to impaired immunostimulatory abilities of these cells. Our observations shed light on the cellular mode of action and the immunomodulatory effect of Rabeximod
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