7,464 research outputs found
John Stuart Mill and the Employment of Married Women: Reconciling Utility and Justice
No full textThis paper explores the link between utilitarianism and feminism through the positions of John Stuart Mill. We try to reconcile Mill's conviction about the necessity of establishing equality between sexes with his position concerning the employment of married women. This reconciliation has already been attempted by other researchers. Our perspective is slightly different in that we seek to establish a globally coherent position by examining Mill's various writings in order to evaluate his feminism in terms of his utilitarian philosophy.John Stuart Mill ; Utilitarisme ; Feminisme ;
John Stuart Mill’s projected science of society: 1827-1848
No full textThe purpose of the thesis is to examine John Stuart Mill’s political thought from
about 1827 to 1848 as an exercise in intellectual history. It focuses, first, on Mill’s view,
formulated by the late 1830s, that contemporary society was ‘civilized’, and second, on
his project of a science of society, which he aspired to develop in the late 1830s and
early 1840s.
By the late 1830s, Mill came to the view that his contemporary society was a
‘commercial society or civilization’, dominated by the middle, commercial class. The
first part of my thesis, constituted by Chapters 2-4, discusses the way in which Mill
formed his notion of civilization, and what he meant by the term ‘civilization’. Mill paid
attention to the implications of the rise of the middle class, and regarded such
phenomena of contemporary society as the corruption of the commercial spirit and
excessive social conformity as an inevitable consequence of the rise of the middle class.
The second part of the thesis, constituted by Chapters 5-9, examines Mill’s
projected science of society. In the late 1830s and early 1840s, Mill attempted to
develop a new science of society whose subject-matter was the nature and prospects of
commercial, civilized society. This aspiration culminated in A System of Logic,
published in 1843. In examining Mill’s projected science, I pay particular attention to
the fact that he conceived new sciences of history and of the formation of character,
both of which were indispensable in his project, although he failed to give a complete
account of these sciences. My thesis shows that the implications of his interest both in
history and in the formation of character are more significant than Mill scholars have
assumed
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
George MacLeod’s open-air preaching: performance and counter-performance
No full textStuart Blythe uses the methodology of performance to analyse George MacLeod’s open-air preaching. He points out that MacLeod’s preaching was derived from a theology of the incarnation, and an understanding of the paradoxes and dichotomies of common human life. This preaching, Blythe suggests, was also a counter-performance in the context of outlooks and ideologies inimical to the gospel. The paper raises interesting issues related to preaching as performance, and the further question as to whether or not the life and work of the Church as a whole might now be better understood as a counter-performance.Publisher PD
Aholy place is the hearth-stone
No full textAn item of correspondence, including a poem titled "A holy place is the hearth-stone", in the George Woodard and Gene Smith letters collection
Global conservation outcomes depend on marine protected areas with five key features
No full textIn line with global targets agreed under the Convention on Biological Diversity, the number of marine protected areas (MPAs) is increasing rapidly, yet socio-economic benefits generated by MPAs remain difficult to predict and under debate. MPAs often fail to reach their full potential as a consequence of factors such as illegal harvesting, regulations that legally allow detrimental harvesting, or emigration of animals outside boundaries because of continuous habitat or inadequate size of reserve. Here we show that the conservation benefits of 87 MPAs investigated worldwide increase exponentially with the accumulation of five key features: no take, well enforced, old (>10 years), large (>100km2), and isolated by deep water or sand. Using effective MPAs with four or five key features as an unfished standard, comparisons of underwater survey data from effective MPAs with predictions based on survey data from fished coasts indicate that total fish biomass has declined about two-thirds from historical baselines as a result of fishing. Effective MPAs also had twice as many large (>250mm total length) fish species per transect, five timesmore large fish biomass, and fourteen times more shark biomass than fished areas. Most (59%) of the MPAs studied had only one or two key features and were not ecologically distinguishable from fished sites. Our results show that global conservation targets based on area alone will not optimize protection of marine biodiversity. More emphasis is needed on better MPA design, durable management and compliance to ensure that MPAs achieve their desired conservation value.Fil: Graham, J. Edgar. University of Tasmania; AustraliaFil: Stuart Smith, Rick D.. University of Tasmania; AustraliaFil: Willis, Trevor J.. University of Portsmouth; Reino UnidoFil: Kininmonth, Stuart. University of Tasmania; Australia. Stockholms Universitet; SueciaFil: Baker, Susan C.. University of Tasmania; AustraliaFil: Banks, Stuart. Charles Darwin Foundation; EcuadorFil: Barrett, Neville S.. University of Tasmania; AustraliaFil: Becerro, Mikel A.. Natural Products and Agrobiology Institute; EspañaFil: Bernard, Anthony T. F.. South African Environmental Observation network; SudáfricaFil: Berkhout, Just. University of Tasmania; AustraliaFil: Buxton, Colin D.. University of Tasmania; AustraliaFil: Campbell, Stuart J.. Wildlife Conservation Society; Estados UnidosFil: Cooper, Antonia T.. University of Tasmania; AustraliaFil: Davey, Marlene. University of Tasmania; AustraliaFil: Edgar, Sophie C.. Department of Water; AustraliaFil: Försterra, Günter. Pontificia Universidad Católica de Valparaíso; ChileFil: Galvan, David Edgardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; ArgentinaFil: Irigoyen, Alejo Joaquin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; ArgentinaFil: Kushner, David J.. United States National Park Service; Estados UnidosFil: Moura, Rodrigo. Universidade Federal do Rio de Janeiro; BrasilFil: Parnell, P. Ed. University of California at San Diego. Scripps Institution of Oceanography; Estados UnidosFil: Shears, Nick T.. The University Of Auckland; Nueva ZelandaFil: Soler, German. University of Tasmania; AustraliaFil: Strain, Elisabeth M. A.. Universidad de Bologna; ItaliaFil: Thomson, Russell J.. University of Tasmania; Australi
Pre-existing trauma and COVID-19: RCPsych COVID-19 Members' Webinar
No full textThe thirteenth of our one-hour webinars took place on Thursday 25 June, focusing on COVID-19: Trauma, Containment and Recovery and included the following speakers:
Organisational containment of anxiety during the pandemic
Dr Jo O'Reilly.
Pre-existing trauma and COVID-19
Dr Jo Stubley.
Managing pandemic related stress: The benefits of gardening and connecting to nature
Dr Sue Stuart-Smith.
This was followed by a live Q&A session, facilitated by Dr Maria Eyres, Academic Secretary, Faculty of Medical Psychotherapy
Responding to accents after experiencing interactive or mediated speech
No full textVery little known is about how speakers learn
about and/or respond to speech experienced
without the possibility for interaction. This paper
reports an experiment which considers the effects
of two kinds of exposure to speech (interactive or
non-interactive mediated) on Scottish English
speakers’ responses to another accent (Southern
British English), for two processing tasks,
phonological awareness and speech production.
Only marginal group effects are found according to
exposure type. The main findings show a
difference between subjects according to exposure
type before exposure, and individual shifts in
responses to speech according to exposure type
Redemption in the work of Francis Stuart
No full textThe idea of redemption is central to an understanding of the work
of Francis Stuart. Through an examination of its development and
expression, it is possible to demonstrate the integrity of his work and
its distinctive qualities. Such a demonstration is necessary because
Stuart's writing has been subjected to comparatively little scholarly
inquiry, although reviews of his work, especially that produced since
1949, suggest that it is impressive and important.
First, a general background to Stuart's work, a discussion of the
special problems associated with reading it, and a summary of his corpus
is provided. This indicates that the idea of redemption is important to
his earliest writing. The state of redemption is shown to be a
necessary apotheosis for Stuart's outcast heroes; it involves spiritual
suffering through which may be found a sense of reintegration and a
higher reality. This is expressed through interrelated themes such as
those of gambler, artist and ordinary man; mystic and criminal; sacred
and profane love; and spirituality and the mundane. The nature of the
redemptive experience is further elaborated by distinctive, complex
motifs, especially the hare, the ark and the woman-Christ. Their
recurrence provides an important element in the unity of Stuart's work.
Because Stuart's idea of the outcast raises important biographical
questions, an examination of the relationship between Stuart's life and
his work is made. Finally, the way in which the idea of redemption
exists in the language structures of Stuart's novels is examined, with
especial reference to his most recent work, The High Consistory. The
thesis shows that the development of the these of redemption
demonstrates the integrity of Stuart's work
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