1,721,840 research outputs found
Smith-Ryan, A R, WX3453
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/418230Surname: SMITH-RYAN. Given Name(s) or Initials: A R. Military Service Number or Last Known Location: WX3453. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 33626.241687
Item: [2016.0049.50491] "Smith-Ryan, A R, WX3453
Regal's Rundown with Sam Smith: Ryan Haggstrom
Smith, Shawn. (2015). Regal's Rundown with Sam Smith: Ryan Haggstrom. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/254253
Identification, Characterization and Function of Voltage-Gated and Two-Pore-Domain Potassium Channels in the Mouse Myometrium.
I am interested in the contractility and electrical excitability in the uterus at the level of individual uterine myocytes throughout gestation. 1 believe by determining potential targets for functional changes in uterine excitability I may be able to uncover the key player(s) in the regulation of resting membrane potential, the onset of labor, and thus uterine contractility. Potassium currents play important roles in the regulation of contraction in many muscles, including cardiac and visceral smooth muscle. By virtue of their ability to set resting membrane potential and exert inhibitory effects, the alterations in outward currents carried by voltage-gated (Kv) and two-pore-domain (K2P) potassium channels are key points of regulation in many excitable cells. Despite these facts little is known about the role of Kv or K2P potassium channels in the regulation of uterine contractility, and certainly nothing is known about the possible involvement of ß subunits and accessory proteins in the regulation of Kv channels and currents in myometrium from any species.|I have observed a potent contractile effect of the Kv channel blocker 4- aminopyridine (4-AP) in nonpregnant mouse myometrium, a response which is not mediated by nerves, the endometrium, or the large-conductance, voltage-activated potassium (BK) channel, and which disappears entirely in term pregnant myometrium. I have begun to explore the possibility that Kv channels play a role in uterine contractility. I have found numerous Kv channel a subunits expressed in nonpregnant mouse myometrium, including several known to be sensitive to 4-AP blockade. Furthermore, almost all of these Kv channel a subunits are expressed in the term-pregnant myometrium, except for Kv4.3 which disappears in term pregnant tissues, coincident with a loss in transient outward current (A-type) known to be carried by certain Kv channels including Kv4.3. In addition to these findings we have also uncovered a dramatic reduction in two of the K2P potassium channel proteins, TASK-1 and TREK-1. These protein levels are dramatically reduced, although at different time points, throughout pregnancy. TREK-1 protein reductions occur within the first 7 days of gestation and remain at significantly reduced levels throughout gestation. TASK-1 protein expression occurs later in gestation than does TREK-1 protein expression and appears to be dramatically reduced between the 15lh and 20th day of pregnancy. The reductions of specific Kv and K2P proteins gives further evidence for a potential role of each of these channel families in the regulation of uterine contractility throughout gestation and parturition.ProQuest Traditional Publishing Optionxviii, 141 page
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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