16,223 research outputs found
TANDEM MAGNETIC REFRIGERATOR FOR 1.8-K
No full textA tandem magnetic refrigerator has been developed for continuous operation between 4.2 and 1.8 K. This paper presents the design, computer simulation and construction of the prototype machine. The- regenerative concept is employed in the magnetic refrigerator to obtain a cascaded magnetic Carnot cycle effect along the temperature axis from the cold end to the warm end. Entropy pumping action from the cold heat reservoir to the warm heat reservoir occurs in the active magnetic regenerator. The inherent sources of irreversibility in regenerative magnetic refrigerators, i.e. heat capacity imbalance between magnetic refrigerant and heat transport medium, helium entrainment and dead volume effect, have been minimized by design optimization of the system components. The magnetic system of the tandem refrigerator has two virtually identical units, each consisting of a gadolinium gallium garnet (GGG; Gd3Ga5O12) magnetic core, a superconducting magnet, a warm end heat exchanger and a cold end heat exchanger. These components are united by a cryogenic displacer which shuttles the heat transport medium, subatmospheric He-3 gas, between the two units. The prototype of the designed magnetic refrigerator has operated continuously, producing a net refrigeration rate of 12 mW per magnetic core at 1.8 K
quinnj/JSON3.jl: v1.14.0
No full text<h2>JSON3 v1.14.0</h2>
<p><a href="https://github.com/quinnj/JSON3.jl/compare/v1.13.2...v1.14.0">Diff since v1.13.2</a></p>
<p><strong>Merged pull requests:</strong></p>
<ul>
<li>add nested getindex to precompile (#271) (@oscardssmith)</li>
<li>support Arrow on 1.9+ via pkg extension (#274) (@palday)</li>
</ul>
<p><strong>Closed issues:</strong></p>
<ul>
<li>JSON3.read files directly (#241)</li>
</ul>
Immunohistochemical quantitation of androgen receptor expression using color video image analysis
No full textBackground: The immunostaining features of the androgen receptor (AR) have been studied in prostate cancer (CaP) to predict the outcome of androgen deprivation therapies. We have developed an automatic video color image analysis system for quantitation of AR expression in large samples of prostatic nuclei. Methods: Essential criteria of immunostaining have been examined to establish a linear relationship between AR protein content and mean optical density (MOD) of the immunoperoxidase-substrate reaction product. Titration of monoclonal AR antibody, F39.4.1, and concentration and reaction time of substrate were optimized using color video image analysis. The methodology was tested twice. First, CWR22 human CaP xenograft specimens, harvested from testosterone (T)-stimulated, castrated and T-resupplemented mice, were immunostained to demonstrate the dependence of AR expression on serum androgen levels. Second, AR expression was measured in archived clinical specimens. Results: In CWR22 tumor-bearing mice castrated for 6 days, AR MOD decreased to 57% of T-stimulated, intact mice. After 72 hrs of T treatment, AR MOD returned to the level measured in T-stimulated, intact mice. Sixteen radical prostatectomy specimens and 16 transurethral resection of prostate (TURP) specimens were double-labeled with F39.4.1 and anti-cytokeratin MAb (13 beta E12) specific for basal epithelial cells. Benign epithelial cells exhibited lower AR MOD in prostatectomy compared to TURF specimens (P < 0.01). Differences in AR immunostaining intensity may have resulted from differences in tissue fixation of whole organ versus small tissue specimens. Conclusions: AR immunostaining can be quantitated accurately using optimized immunohistochemical criteria and video image analysis. Cytometry 35:2-10, 1999. (C) 1999 Wiley-Liss, Inc
Global Map Of Trachoma Distribution: Significant Step For Preventing Blindness - 17 November 2010
No full textATLANTA - A new map showing the distribution of the eye infection trachoma promises to help overcome this leading cause of blindness, according to a report at the American Society of Tropical Medicine & Hygiene Annual Meeting in Atlanta, Georgia (November 3-7, 2010). Jennifer Smith of the London School of Hygiene and Tropical Medicine talks about the map and discusses the practical steps that can be taken to overcome trachoma
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Materials and superconducting electronics
No full textThis report consists of a dialog by Dr. James L. Smith at the Superconducting Digital Circuits and Systems Conference. (JL
Disparities in registration and use of an online patient portal among older adults: findings from the LitCog cohort
No full text(C) The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved.Financial disclosure: This project was supported by the
National Institute on Aging (R01 AG030611), the National
Center for Research Resources (5UL1RR025741), and the
National Center for Advancing Translational Sciences (Grant
8UL1TR000150). The content is solely the responsibility of the
authors and does not necessarily represent the official views of
the National Institutes of Health. Smith is currently supported
by a Cancer Research UK Fellowship
Canadian Federalism and Federation in Comparative Perspective
No full textThis second edition renews the promise of the first: it offers a fresh and comprehensive exploration of the complexity of Canadian federal politics. It begins with a comprehensive section on constitutional politics, which examines topics ranging from executive federalism to multiculturalism including new chapters on judicial review and the division of powers, Aboriginal governance and federalism, and the implication of treaty rights for self-governance. This is followed by seven chapters that both provide a select survey of public policy areas and explore the impact of federal-provincial relations on policy evolution and outcomes. Updated chapters on trade policy, labour policy, the environment, regionalism, and, of course, health care are all to be found, alongside new work on social assistance and Canadian federalism and federation in comparative perspective. Throughout, the book reveals the visions that have animated Canada's longstanding constitutional debates, the role of executive federalism and the courts in relation to the evolution of federalism, and the essential dynamism of policy development. Together they demonstrate that, despite the lack of a formal constitutional agreement, important changes are occurring in the Canadian federal system
Psychosocial capacity building in response to cascading disasters: A culturally informed approach
No full textThe dominant paradigm guiding mental health professionals responding to major disasters is the field of 'disaster mental health', which historically focused more on psychological factors than social factors, privileging individual over collective interventions. However, resilience to complex events is a result of multiple drivers, such as social networks and local culture, that must be considered together in the assessment and planning process. This paper adopts a multi-disciplinary perspective for disaster response, applying a social-ecological approach to disaster risk reduction which has been developed through practice and a review of the literature. In particular, we investigated how psychosocial healing, collective efficacy and social justice as intertwined aspects of the recovery process may inhibit the escalation of cascading disasters. The article argues that psychosocial capacity building can be used in disaster preparation as well as to respond to cascading events, as the escalation of secondary emergencies caused by the loss of vital services can heavily influence collective behaviors, and hinder the response capacity of emergency services. Our research suggests that adopting a multi-systemic approach, drawing on local cultural practices, can deepen the capacity of local people to take control over their own process of healing and psychosocial restoration, enhancing a sustainable recovery process. The conclusions suggest some possible applications for responders, utilizing groups and activities, and raise questions for researchers in the field
Entomopatogen nematode exploration and virulency against Spodoptera frugiperda J.E Smith
No full textCorn (Zea mays L) is a very important food and animal feed after rice. One of the important pests that attack corn plants is Spodoptera frugiperda J.E Smith. This pest is a new pest and is a major pest in corn. In pest control, farmers generally use synthetic chemicals. In an effort to reduce these negative impacts synthetic chemical, entomopathogenic nematode (NEP) was chosen as one of the more environmentally friendly control techniques. This study aims to obtain NEP isolates, population density and virulence against S. frugiperda. This research was conducted at the Plant Protection Laboratory, Bengkulu University from December 2019 to April 2020. This study used a Factorial Completely Randomized Design (CRD) with 4 treatments and 5 replications. The treatments consisted of NEP concentrations : 0 Jl / ml; 200 Jl / 1ml; 400 Jl / 2ml; 600 Jl / 3ml originating from Bengkulu and Kepahiang isolates. Each experiment consisted of 3 S. frugiperda larvae. The results showed that the NEP obtained from each region, namely the genus Steinermatidae. Population density of 9,005 NEP / 5ml in the Kepahiang area and 6,837 NEP / 5ml in the Bengkulu region. NEP virulence test against S. frugiperda larvae showed that 200 Jl / ml concentration was able to control S. frugiperda in maize , and can kill pests within 4 days. With an LC50 value of 163.5 Jl / ml in Kepahiang isolates and 186.5 Jl / ml in Bengkulu isolates
NMR-STUDY OF THE EXCHANGE-REACTIONS BETWEEN ALLYLTRIALKYLTIN COMPOUNDS AND LEWIS-ACIDS .1. EXCHANGES WITH BORON TRIBROMIDE AND TRIFLUORIDE AND TITANIUM TETRACHLORIDE
No full textReactions between BX3 (X = F or Br) and TiCl4 with R1CHCHCH2SnR3 [I, R = Me, Bu or cyclohexyl(Cy); R1 = H or Me] have been studied by NMR spectroscopy. Allyl group-bromine exchanges occur between I and BBr3 at −60 °C; at higher temperatures (c. −10 °C) I (R = Me or Bu but not Cy) reacts further to give R2SnBr2. No allyl group-fluorine exchange products were detected from the reaction between I and BF3·Et2O below −20 °C. However, at 25 °C I (R = Me, R1 = H) reacts readily with BF3·Et2O, the predominant soluble tin product being Me4Sn. Compounds I and TiCl4 at 30 °C rapidly produce R3SnCl and [RCHCHCH2]TiCl3
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