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    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Sequencing of mitochondrial genome with CRISPR/Cas9 technology and nanopore sequencing

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    Genetske spremembe v mitohondrijskem genomu so pomemben dejavnik pri razvoju mitohondrijskih bolezni. Te uvrščamo v skupino heterogenih bolezni, za katere je značilno pomanjkanje celične energije. Priprava knjižnice za sekvenciranje z uporabo CRISPR/Cas9 in tehnologija sekvenciranja DNA z nanoporo nam omogočata obogatitev mitohondrijskega genoma brez tarčnega pomnoževanja s PCR. Produkt takšnega sekvenciranja so dolgi odčitki (>10 kb), ki omogočajo sestavljanje mitohondrijskega genoma de novo in detekcijo večjih delecij ter ponovitvenih regij. Pri magistrskem delu smo dokazali, da lahko s tehnologijo CRISPR/Cas9 in sekvenciranjem z nanoporo obogatimo mitohondrijski genom in generiramo odčitke, ki pokrijejo celotno dolžino mitohondrijske DNA (mtDNA). Preverili smo različne bioinformacijske pristope, ki jih lahko uporabljamo pri analizi podatkov in rezultate med sabo primerjali za iskanje genetskih sprememb. Nato smo preverili zmožnosti tehnologije sekvenciranja z nanoporo za detekcijo nizkostopenjskih heteroplazmij, pri katerih celica vsebuje nizek delež mutirane mtDNA v primerjavi z mtDNA divjega tipa. Ugotovili smo, da lahko s to tehnologijo detektiramo do 10 % heteroplazmije. Detekcija heteroplazmije je pomembna pri diagnozi mitohondrijskih bolezni, saj lahko učinek ozkega grla med oogenezo in embriogenezo vodi do razvoja višje stopnje heteroplazmije, ki povzroči fenotipsko izražanje bolezni. Tehnologija sekvenciranja z nanoporo nam omogoča tudi identifikacijo modificiranih baz, ki so pomembne pri regulaciji izražanja genov. Pri analizi smo identificirali prisotnost 5-metilcitozinov na mtDNA in ugotovili, da je njihova frekvenca nizka. Uporaba zgoraj omenjenega pristopa bi omogočila globlje razumevanje mitohondrijske genetike in epigenetike ter posledično delovanja mitohondrija.Genetic variants of mitochondrial genome are an important driver of mitochondrial disorder pathology. Mitochondrial disorders are heterogeneous diseases characterized by a lack of cellular energy. Using targeted nanopore sequencing in combination with CRISPR/Cas9 technology enables amplification-free sequence enrichment of mitochondrial DNA (mtDNA). Nanopore sequencing produces long reads (> 10 kb), which improves de novo assembly and detection of large sporadic deletions and tandem repeats. In this study, we demonstrated that this technology enriches the mitochondrial genome and generates full-length nanopore reads of mtDNA. We tested different bioinformatics approaches for analyzing the data and compared the results of these approaches for variant calling. We verified the ability of nanopore sequencing for the detection of low-level DNA heteroplasmy, where the cell contains a low proportion of mutated mtDNA molecules compared to wild-type mtDNA. We determined that nanopore sequencing is able to detect down to 10 % heteroplasmy. Detecting a low-heteroplasmic variance is crucial for the diagnosis of mitochondrial diseases, as the bottleneck effect during oogenesis and embryogenesis can lead to the sampling and subsequent expansion of rare mutant mtDNA. Nanopore sequencing technology is also able to detect modified bases that are important for epigenetic control of gene expression. We identified the presence of 5-methylcytosines on mtDNA and observed that their frequency is low. The application of the presented approach would provide deeper understanding of mitochondrial genetics, epigenetics and consequently, of mitochondrial biology

    Research on the resistance of certain consolidants for picture layers to selected fungi

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    V magistrskem delu smo proučevali rast izbranih gliv na nekatera pogosto uporabljena sredstva v konservatorstvu-restavratorstvu za utrjevanje slikovnih plasti. Izbrali smo naravne in sintetične materiale z različnimi lastnostmi. Materiale smo nanesli na različne podlage: na vzorce lesa, platna in stekla. Vzorce na lesu smo pripravili po zgledu stratigrafije lesenih kipov, s klejno-kredno podlogo in oljno barvo. Vzorci na platnu so sledili stratigrafiji klasičnih oljnih slik. Vzorce na steklu pa smo pripravili z namenom preverjanja potrebe gliv po specifičnem substratu. Na tako pripravljene vzorce smo nanesli izbrane materiale za utrjevanje: zajčji kožni klej, ribji klej, Lascaux medij za utrjevanje 4176 (Medium for consolidation 4176), Beva 371, Paraloid B-72, Regalrez 1126 in Lascaux Hydro-Grund (Hydro-Sealer 2001), samo na stekleno podlago pa smo nanesli še Calaton, Sokrat 2804, Plextol D498 in Plextol B500. Vzorce smo razdelili v pet skupin: prva je služila kontroli (neinokulirani vzorci), ostale pa smo inokulirali s štirimi vrstami gliv: Aspergillus destruens, Bjerkandera adusta, Chaetomium globosum in Aureobasidium pullulans. Vzorce smo namestili v vlažne komore z relativno zračno vlago med 55 in 80 %) in jih inkubirali pri temperaturi 15 °C, podobni tisti v cerkvah in v depojih. Cilj poskusa je bila pridobitev podatkov o primernosti uporabe materialov v pogojih, ki morda niso idealni za umetnino, vendar podpirajo razvoj gliv. Za pridobitev širšega vpogleda na vrste gliv, ki uspevajo na lesenih predmetih kulturne dediščine, smo odvzeli vzorce z oltarja iz cerkve sv. Areha na Pohorju. Izsledki naloge so bili tudi praktično uporabljeni pri izbiri materiala za utrjevanje kipa sv. Jožefa iz cerkve sv. Danijela v Štanjelu.The Master Thesis\u27 topic presents a laboratory study of the growth of selected fungi on materials frequently used in restoration with the purpose to consolidate picture layers. Natural and synthetic materials with different properties were selected and applied on wood, canvas and glass bases. Samples on wood were prepared according to traditional stratigraphy of wooden sculptures, with a hide glue and chalk lining and oil paint. Samples on canvas followed the stratigraphy of classic oil paintings. Samples on glass contained the test material only, and were used in our experiment with the purpose of verifying the requirements of fungi for the base substrate. The following materials for consolidation were then applied to the prepared bases: rabbit skin glue, fish glue, Lascaux medium for consolidation 4176, Beva 371, Paraloid B-72, Regalrez 1126 and Lascaux Hydro-Grund (Hydro-Sealer 2001). Additional materials applied to glass base only were: Calaton, Sokrat 2804, Plextol D498 and Plextol B500. The samples were divided into five groups: the first group was for control purposes (not inoculated), the others were inoculated with representatives of four fungal species: Aspergillus destruens, Bjerkandera adusta, Chaetomium globosum and Aureobasidium pullulans. All samples were incubated in moist chambers with relative humidity between 55 and 80% at 15 °C, the temperature similar to that in churches and depots. The goal of the experiment was to evaluate the appropriateness of the use of materials in conditions that support the development of fungi but may not be ideal for the artwork itself. In order to gain a broader insight into the types of fungi that thrive on the wooden items of cultural heritage, samples were taken from the altar of the church of St. Areh from Pohorje. The results of the thesis were also practically applied in the selection of the appropriate material used for the consolidation of the statue of St. Joseph from the Church of St. Danijel in Štanjel.
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