196,014 research outputs found
The estensive genital warts ressembling a giant condyloma of Busche-Loewenstein: a case report.
No full textDr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
The clinical pattern variations and epidemiology of deep seated tinea capitis
No full textStandardni obrazac kliničke slike dermatomikoze vlasišta uzrokovane gljivom
vrste Microsporum canis jest površinska dermatomikoza karakterizirana
cirkumskriptnim eritemom, adherentnom deskvamacijom i poremećajem integriteta
vlasi. Zadnjih dvadesetak godina primjećuje se, međutim, da ista vrsta gljive može
biti i uzročnikom vrlo impresivne kliničke slike duboke mikoze vlasišta (kerion Celsi)
karakterizirane granulomatoznom upalom, tumoroznom masom i obilnom
pustuloznom sekrecijom, što, uzevši u obzir tipičnu pojavnost u dječjoj dobi, može
ozbiljno uticati na kvalitetu zdravlja djeteta i opravdanu zabrinutost roditelja. Razlog
pojavi da ista vrsta gljive može uzrokovati dva klinički vrlo različita obrasca kliničke
slike mikoze vlasišta nije još objašnjen.
Osnovna pretpostavka ovog istraživanja bila je da različiti genotipovi gljive
vrste M. canis uzrokuju površinsku odnosno duboku mikozu vlasišta kao dva
zasebna klinička entiteta i da genotipske razlike unutar gljive vrste M. canis su
odgovorne za pojavu različite virulentnosti gljive, te time i za pojavu različitih kliničkih
manifestacija mikrosporoze vlasišta. Primarni cilj istraživanja bio je ispitati genotipsku
varijabilnost izolata gljive vrste M. canis u ispitanika s površinskom i dubokom
mikozom vlasišta.
U ispitivanje je bilo uključeno 60 ispitanika - djeca u dobi od 2 do 12 godina
(30 ispitanika s površinskom i 30 ispitanika s dubokom mikozom vlasišta). Primjenom
metodologije mikološke obrade u svih ispitanika je identificirana vrsta M. canis.
Morfološka identifikacija je potvrđena molekularnom metodom PCR-RFLP
(Polymerase Chain Reaction-Restriction Fragment Length Polymorphism),
amplifikacijom ITS1-5.8S-ITS2 regije i primjenom HinfI restrikcijskog enzima. Za
subtipizaciju M. canis korištena je RAPD (Random Amplified Polimorphic DNA)
metoda, primjenom (ACA)5 i (GACA)4 početnica. Korištenjm (ACA)5 početnice
dobiven je jedinstveni RAPD profil. Primjenom (GACA)4 početnice identificirana su
dva RAPD profila. U epidemiološkom dijelu našeg istraživanja zaključili smo da je (i dalje) M.
canis vodeći uzročnik dermatomikoza vlasišta u Republici Hrvatskoj. Učestalost
zoofilne mikrosporoze vlasišta još je uvijek visoka, no, tijekom desetogodišnjeg
razdoblja (2006.-2015.) vidljiv je trend opadanja broja kulturom potvrđenih
dermatomikoza vlasišta u prvih pet godina istraživanja, uz stabilizaciju broja
pozitivnih kultura zadnjih 5 godina. Vidljiv je i statistički značajno veći udio
dermatomikoze vlasišta unutar svih kliničkih manifestacija dermatofitoza u zadnje 3
godine istraživanja (2013.-2015.).
Na temelju rezultata molekularno-medicinskog dijela istraživanja nije utvrđena
statistički značajna razlika raspodjele prema PCR profilu za tip kliničke slike
(površinska versus duboka dermatomikoza vlasišta). No, istraživanje je pokazalo da
M. canis nije genotipski jednoobrazan. Primjenom RAPD metode i korištenjem
(GACA)4 početnice identificirali smo dva profila među ispitanim sojevima M. canis, što
pokazuje da M. canis ipak nije „genotipski stabilan“ kako pokazuju dosadašnje
studije.
Na temelju rezultata našeg istraživanja može se, između ostalog zaključiti da
tip kliničke slike mikrosporoze vlasišta (površinska versus duboka mikoza vlasišta)
nije rezultat infekcije točno određenim genotipom gljive vrste M. canis. Oba tipa
kliničke slike mikrosporoze vlasišta mogu biti uzrokovana istim genotipom M. canis.Tinea capitis caused by Microsporum canis is usually noninflammatory.
However, progressive number of severe kerion like tinea capitis (TC) due to M. canis
has been recently registered. Providing that the same fungal species might evoke
different clinical patterns, interspecies polymorphism within M. canis isolates might
have been responsible for this phenomenon.
The aim of this study was to examine genotypic variability among isolates of
M. canis from patients with superficial and deep seated tinea capitis.
Sixty strains of M. canis from patients with both superficial and deep seated
tinea capitis have been isolated and identified to the species level using standard and
advanced mycological procedure techniques. Morphological identification was
confirmed by molecular methods PCR-RFLP (Polymerase Chain Reaction-Restriction
Fragment Length Polymorphism). After amplification of ITS1-5.8S-ITS2 region, the
PCR product was exposed to restriction enzyme HinfI. All strains of M. canis had
identical pattern on gel electrophoresis. For sub typing of M. canis isolates the RAPD
(Random Amplified Polimorphic DNA) has been perfomed using (ACA)5 and (GACA)4
primers. After RAPD amplification with (ACA)4 primer, among all M. canis isolates
only one RAPD profile was determined, whereas using (GACA)4 primer two different
band patterns were confirmed.
According to the results of the epidemiological part of our study M. canis
remained the main causative agent of TC in Croatia. The incidence of TC remained
high during the ten-years period (2006-2015), but decrease in the incidence of TC
was observed in the first 5 years, with stable incidence of TC during the last 5 years
of the study period. A statistically significant increase of TC among all fungal skin
infections during the last 3 years was observed. The association between RAPD profiles and certain clinical type of tinea
capitis was not determined by the use of GACA4 primer . Results of most molecular
studies show that there is no clonal differentiation within M. canis. Moreover, using
the same (GACA)4 primer M. canis was found not to be genotypically unique.
However, furhter investigations on larger group of patiens might be required in order
to elucidate this problem more precisely
The clinical pattern variations and epidemiology of deep seated tinea capitis
No full textStandardni obrazac kliničke slike dermatomikoze vlasišta uzrokovane gljivom
vrste Microsporum canis jest površinska dermatomikoza karakterizirana
cirkumskriptnim eritemom, adherentnom deskvamacijom i poremećajem integriteta
vlasi. Zadnjih dvadesetak godina primjećuje se, međutim, da ista vrsta gljive može
biti i uzročnikom vrlo impresivne kliničke slike duboke mikoze vlasišta (kerion Celsi)
karakterizirane granulomatoznom upalom, tumoroznom masom i obilnom
pustuloznom sekrecijom, što, uzevši u obzir tipičnu pojavnost u dječjoj dobi, može
ozbiljno uticati na kvalitetu zdravlja djeteta i opravdanu zabrinutost roditelja. Razlog
pojavi da ista vrsta gljive može uzrokovati dva klinički vrlo različita obrasca kliničke
slike mikoze vlasišta nije još objašnjen.
Osnovna pretpostavka ovog istraživanja bila je da različiti genotipovi gljive
vrste M. canis uzrokuju površinsku odnosno duboku mikozu vlasišta kao dva
zasebna klinička entiteta i da genotipske razlike unutar gljive vrste M. canis su
odgovorne za pojavu različite virulentnosti gljive, te time i za pojavu različitih kliničkih
manifestacija mikrosporoze vlasišta. Primarni cilj istraživanja bio je ispitati genotipsku
varijabilnost izolata gljive vrste M. canis u ispitanika s površinskom i dubokom
mikozom vlasišta.
U ispitivanje je bilo uključeno 60 ispitanika - djeca u dobi od 2 do 12 godina
(30 ispitanika s površinskom i 30 ispitanika s dubokom mikozom vlasišta). Primjenom
metodologije mikološke obrade u svih ispitanika je identificirana vrsta M. canis.
Morfološka identifikacija je potvrđena molekularnom metodom PCR-RFLP
(Polymerase Chain Reaction-Restriction Fragment Length Polymorphism),
amplifikacijom ITS1-5.8S-ITS2 regije i primjenom HinfI restrikcijskog enzima. Za
subtipizaciju M. canis korištena je RAPD (Random Amplified Polimorphic DNA)
metoda, primjenom (ACA)5 i (GACA)4 početnica. Korištenjm (ACA)5 početnice
dobiven je jedinstveni RAPD profil. Primjenom (GACA)4 početnice identificirana su
dva RAPD profila. U epidemiološkom dijelu našeg istraživanja zaključili smo da je (i dalje) M.
canis vodeći uzročnik dermatomikoza vlasišta u Republici Hrvatskoj. Učestalost
zoofilne mikrosporoze vlasišta još je uvijek visoka, no, tijekom desetogodišnjeg
razdoblja (2006.-2015.) vidljiv je trend opadanja broja kulturom potvrđenih
dermatomikoza vlasišta u prvih pet godina istraživanja, uz stabilizaciju broja
pozitivnih kultura zadnjih 5 godina. Vidljiv je i statistički značajno veći udio
dermatomikoze vlasišta unutar svih kliničkih manifestacija dermatofitoza u zadnje 3
godine istraživanja (2013.-2015.).
Na temelju rezultata molekularno-medicinskog dijela istraživanja nije utvrđena
statistički značajna razlika raspodjele prema PCR profilu za tip kliničke slike
(površinska versus duboka dermatomikoza vlasišta). No, istraživanje je pokazalo da
M. canis nije genotipski jednoobrazan. Primjenom RAPD metode i korištenjem
(GACA)4 početnice identificirali smo dva profila među ispitanim sojevima M. canis, što
pokazuje da M. canis ipak nije „genotipski stabilan“ kako pokazuju dosadašnje
studije.
Na temelju rezultata našeg istraživanja može se, između ostalog zaključiti da
tip kliničke slike mikrosporoze vlasišta (površinska versus duboka mikoza vlasišta)
nije rezultat infekcije točno određenim genotipom gljive vrste M. canis. Oba tipa
kliničke slike mikrosporoze vlasišta mogu biti uzrokovana istim genotipom M. canis.Tinea capitis caused by Microsporum canis is usually noninflammatory.
However, progressive number of severe kerion like tinea capitis (TC) due to M. canis
has been recently registered. Providing that the same fungal species might evoke
different clinical patterns, interspecies polymorphism within M. canis isolates might
have been responsible for this phenomenon.
The aim of this study was to examine genotypic variability among isolates of
M. canis from patients with superficial and deep seated tinea capitis.
Sixty strains of M. canis from patients with both superficial and deep seated
tinea capitis have been isolated and identified to the species level using standard and
advanced mycological procedure techniques. Morphological identification was
confirmed by molecular methods PCR-RFLP (Polymerase Chain Reaction-Restriction
Fragment Length Polymorphism). After amplification of ITS1-5.8S-ITS2 region, the
PCR product was exposed to restriction enzyme HinfI. All strains of M. canis had
identical pattern on gel electrophoresis. For sub typing of M. canis isolates the RAPD
(Random Amplified Polimorphic DNA) has been perfomed using (ACA)5 and (GACA)4
primers. After RAPD amplification with (ACA)4 primer, among all M. canis isolates
only one RAPD profile was determined, whereas using (GACA)4 primer two different
band patterns were confirmed.
According to the results of the epidemiological part of our study M. canis
remained the main causative agent of TC in Croatia. The incidence of TC remained
high during the ten-years period (2006-2015), but decrease in the incidence of TC
was observed in the first 5 years, with stable incidence of TC during the last 5 years
of the study period. A statistically significant increase of TC among all fungal skin
infections during the last 3 years was observed. The association between RAPD profiles and certain clinical type of tinea
capitis was not determined by the use of GACA4 primer . Results of most molecular
studies show that there is no clonal differentiation within M. canis. Moreover, using
the same (GACA)4 primer M. canis was found not to be genotypically unique.
However, furhter investigations on larger group of patiens might be required in order
to elucidate this problem more precisely
Simulation of thermal plant optimization and hydraulic aspects of thermal distribution loops for large campuses
No full textFollowing an introduction, the author describes Texas A&M University and its utilities system. After that, the author presents how to construct simulation models for chilled water and heating hot water distribution systems. The simulation model was used in a $2.3 million Ross Street chilled water pipe replacement project at Texas A&M University. A second project conducted at the University of Texas at San Antonio was used as an example to demonstrate how to identify and design an optimal distribution system by using a simulation model. The author found that the minor losses of these closed loop thermal distribution systems are significantly higher than potable water distribution systems. In the second part of the report, the author presents the latest development of software called the Plant Optimization Program, which can simulate cogeneration plant operation, estimate its operation cost and provide optimized operation suggestions. The author also developed detailed simulation models for a gas turbine and heat recovery steam generator and identified significant potential savings. Finally, the author also used a steam turbine as an example to present a multi-regression method on constructing simulation models by using basic statistics and optimization algorithms. This report presents a survey of the author??s working experience at the Energy Systems Laboratory (ESL) at Texas A&M University during the period of January 2002 through March 2004. The purpose of the above work was to allow the author to become familiar with the practice of engineering. The result is that the author knows how to complete a project from start to finish and understands how both technical and nontechnical aspects of a project need to be considered in order to ensure a quality deliverable and bring a project to successful completion. This report concludes that the objectives of the internship were successfully accomplished and that the requirements for the degree of Degree of Engineering have been satisfied
The clinical pattern variations and epidemiology of deep seated tinea capitis
No full textStandardni obrazac kliničke slike dermatomikoze vlasišta uzrokovane gljivom
vrste Microsporum canis jest površinska dermatomikoza karakterizirana
cirkumskriptnim eritemom, adherentnom deskvamacijom i poremećajem integriteta
vlasi. Zadnjih dvadesetak godina primjećuje se, međutim, da ista vrsta gljive može
biti i uzročnikom vrlo impresivne kliničke slike duboke mikoze vlasišta (kerion Celsi)
karakterizirane granulomatoznom upalom, tumoroznom masom i obilnom
pustuloznom sekrecijom, što, uzevši u obzir tipičnu pojavnost u dječjoj dobi, može
ozbiljno uticati na kvalitetu zdravlja djeteta i opravdanu zabrinutost roditelja. Razlog
pojavi da ista vrsta gljive može uzrokovati dva klinički vrlo različita obrasca kliničke
slike mikoze vlasišta nije još objašnjen.
Osnovna pretpostavka ovog istraživanja bila je da različiti genotipovi gljive
vrste M. canis uzrokuju površinsku odnosno duboku mikozu vlasišta kao dva
zasebna klinička entiteta i da genotipske razlike unutar gljive vrste M. canis su
odgovorne za pojavu različite virulentnosti gljive, te time i za pojavu različitih kliničkih
manifestacija mikrosporoze vlasišta. Primarni cilj istraživanja bio je ispitati genotipsku
varijabilnost izolata gljive vrste M. canis u ispitanika s površinskom i dubokom
mikozom vlasišta.
U ispitivanje je bilo uključeno 60 ispitanika - djeca u dobi od 2 do 12 godina
(30 ispitanika s površinskom i 30 ispitanika s dubokom mikozom vlasišta). Primjenom
metodologije mikološke obrade u svih ispitanika je identificirana vrsta M. canis.
Morfološka identifikacija je potvrđena molekularnom metodom PCR-RFLP
(Polymerase Chain Reaction-Restriction Fragment Length Polymorphism),
amplifikacijom ITS1-5.8S-ITS2 regije i primjenom HinfI restrikcijskog enzima. Za
subtipizaciju M. canis korištena je RAPD (Random Amplified Polimorphic DNA)
metoda, primjenom (ACA)5 i (GACA)4 početnica. Korištenjm (ACA)5 početnice
dobiven je jedinstveni RAPD profil. Primjenom (GACA)4 početnice identificirana su
dva RAPD profila. U epidemiološkom dijelu našeg istraživanja zaključili smo da je (i dalje) M.
canis vodeći uzročnik dermatomikoza vlasišta u Republici Hrvatskoj. Učestalost
zoofilne mikrosporoze vlasišta još je uvijek visoka, no, tijekom desetogodišnjeg
razdoblja (2006.-2015.) vidljiv je trend opadanja broja kulturom potvrđenih
dermatomikoza vlasišta u prvih pet godina istraživanja, uz stabilizaciju broja
pozitivnih kultura zadnjih 5 godina. Vidljiv je i statistički značajno veći udio
dermatomikoze vlasišta unutar svih kliničkih manifestacija dermatofitoza u zadnje 3
godine istraživanja (2013.-2015.).
Na temelju rezultata molekularno-medicinskog dijela istraživanja nije utvrđena
statistički značajna razlika raspodjele prema PCR profilu za tip kliničke slike
(površinska versus duboka dermatomikoza vlasišta). No, istraživanje je pokazalo da
M. canis nije genotipski jednoobrazan. Primjenom RAPD metode i korištenjem
(GACA)4 početnice identificirali smo dva profila među ispitanim sojevima M. canis, što
pokazuje da M. canis ipak nije „genotipski stabilan“ kako pokazuju dosadašnje
studije.
Na temelju rezultata našeg istraživanja može se, između ostalog zaključiti da
tip kliničke slike mikrosporoze vlasišta (površinska versus duboka mikoza vlasišta)
nije rezultat infekcije točno određenim genotipom gljive vrste M. canis. Oba tipa
kliničke slike mikrosporoze vlasišta mogu biti uzrokovana istim genotipom M. canis.Tinea capitis caused by Microsporum canis is usually noninflammatory.
However, progressive number of severe kerion like tinea capitis (TC) due to M. canis
has been recently registered. Providing that the same fungal species might evoke
different clinical patterns, interspecies polymorphism within M. canis isolates might
have been responsible for this phenomenon.
The aim of this study was to examine genotypic variability among isolates of
M. canis from patients with superficial and deep seated tinea capitis.
Sixty strains of M. canis from patients with both superficial and deep seated
tinea capitis have been isolated and identified to the species level using standard and
advanced mycological procedure techniques. Morphological identification was
confirmed by molecular methods PCR-RFLP (Polymerase Chain Reaction-Restriction
Fragment Length Polymorphism). After amplification of ITS1-5.8S-ITS2 region, the
PCR product was exposed to restriction enzyme HinfI. All strains of M. canis had
identical pattern on gel electrophoresis. For sub typing of M. canis isolates the RAPD
(Random Amplified Polimorphic DNA) has been perfomed using (ACA)5 and (GACA)4
primers. After RAPD amplification with (ACA)4 primer, among all M. canis isolates
only one RAPD profile was determined, whereas using (GACA)4 primer two different
band patterns were confirmed.
According to the results of the epidemiological part of our study M. canis
remained the main causative agent of TC in Croatia. The incidence of TC remained
high during the ten-years period (2006-2015), but decrease in the incidence of TC
was observed in the first 5 years, with stable incidence of TC during the last 5 years
of the study period. A statistically significant increase of TC among all fungal skin
infections during the last 3 years was observed. The association between RAPD profiles and certain clinical type of tinea
capitis was not determined by the use of GACA4 primer . Results of most molecular
studies show that there is no clonal differentiation within M. canis. Moreover, using
the same (GACA)4 primer M. canis was found not to be genotypically unique.
However, furhter investigations on larger group of patiens might be required in order
to elucidate this problem more precisely
2020 European guideline on the management of genital molluscum contagiosum
No full textMolluscum contagiosum is a benign viral epidermal infection associated with high risk of transmission. The guideline is focused on the sexually transmitted molluscum contagiosum. The diagnosis is clinical with characteristic individual lesions, termed ‘mollusca’, seen as dome-shaped, smooth-surfaced, pearly, firm, skin-coloured, pink, yellow or white papules, 2 - 5 mm in diameter with central umbilication. Dermoscopy may facilitate diagnosis. Therapeutic options are numerous, including physical treatments (cautery, curettage and cryotherapy), topical chemical treatments (e.g. podophyllotoxin and imiquimod) or waiting for spontaneous resolution in immunocompetent patients. In pregnancy, it is safe to use physical procedures (e.g. cryotherapy). Immunosuppressed patients develop severe and recalcitrant molluscum lesions that may require treatment with cidofovir, imiquimod or interferon. Patients with molluscum contagiosum infection should be offered to be screened for other sexually transmitted infections
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