136 research outputs found

    Denkmahl der Freundschaft. : Stammbuch A. W. F. und Julie Hoffmann

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    Enthält 32 Stammbucheinträge u.a. von Frierich Güntschmann, E. F. Kranert, Christine Kranert, Fr. Ludewig Köhler, Ottomar Rabenalt, Heinrich Röbel, Louis Schild u.a. Marie Albert, Tanni Listner Louise RaggHandschrift DE-3, GND 2024680-8, Signatur: Yg St. 39Einband: ungebundene Blätter in buntpapierbezogener Kassette, Buntpapier über Pappe, Rollenstempelprägung (Goldprägung), Rücken braun bezogen, mit Rückentitelprägung auf rotem Etikett (Goldprägung), Titelprägung auf grünen Etikett auf Vorderdeckel: A.W. Hoffmann (Goldprägung), auf Rückendeckel: 1825. Mit buntpapierbezogenem Pappumschlag. Im Pappschuber, Marmorpapier über Pappe.Zustand: Papier leicht gebräunt und fleckig32 EinzelblätterEintragungsorte: Breitungen, Dietersdorf, Hermannsacker, Lauchstädt; Roßla, Wippra u.a.1 kol. Federzeichnung Bl. 8; 2 Bleistiftzeichnungen Bl. 10v, 22; 3 farbige Miniaturen: Bl. 23, 24, 25; 1 Haarlocke Bl. 21, 2

    Validation of a cloud-based tele-stroke system reliability in determining national institutes of health stroke scale scores for acute ischemic stroke screening in the emergency department

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    Remote diagnosis; Tele-strokeDiagnóstico remoto; Tele-ictusDiagnòstic remot; Tele-ictusBackground and purpose: The National Institutes of Health Stroke Scale (NIHSS) is the most recommended tool for objectively quantifying the impairment caused by a suspected stroke. Nevertheless, it is mainly used by trained neurologists in the emergency department (ED). To bring forward the NIHSS to the pre-hospital setting, a smartphone-based Telestroke system was developed. It captures the full NIHSS by video, transmits it off-line, and enables assessment by a distant stroke physician. We aimed to compare the reliability of an NIHSS score determined by a neurologist from afar, using the platform with a standard NIHSS assessment performed in the emergency departments. Methods: A multi-center prospective study was conducted in two centers (Vall d'Hebron, Barcelona, and Rambam, Israel). Patients admitted to the ED with suspected stroke had a neurological exam based on the NIHSS, while being recorded by the system. A skilled neurologist rated the NIHSS according to the videos offline. The results were compared with the NIHSS score given by a neurologist at the bedside. Results: A total of 95 patients with suspected stroke were included. The overall intraclass correlation coefficient was 0.936 (0.99 in VdH and 0.84 in Rambam), indicating excellent and good reliability, respectively. Conclusion: Remote stroke assessment based on the NIHSS, using videos segments collected by a dedicated platform, installed on a standard smartphone, is a reliable measurement as compared with the bedside evaluation.The authors declare that this study received funding from CVAID Company. The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article, or the decision to submit it for publication

    Assessment of hemostatic profile in neonates with necrotizing enterocolitis using Rotational Thromboelastometry (ROTEM)

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    Background: This study aimed to explore the hemostatic profile of neonates with necrotizing enterocolitis (NEC) using Rotational Thromboelastometry (ROTEM) and to investigate if ROTEM parameters have the capacity to play a role in the differentiation of NEC from sepsis at the disease onset. Methods: This observational study included 62 neonates (mean gestational age 31.6 weeks and mean birth weight 1620g) hospitalized in a neonatal intensive care unit. The neonates were categorized in three groups: neonates with NEC (Bell stage II and above), neonates with sepsis and healthy neonates and they were matched 1:1:1 with regards to gestational age, delivery mode, and sex. Clinical, laboratory data as well as measurements of ROTEM parameters at disease onset were recorded. Results: ROTEM parameters differed between neonates with NEC and neonates with sepsis, indicating that NEC results in accelerated clot formation and higher clot strength compared to sepsis. The EXTEM CFT and A10 parameters demonstrated the highest diagnostic performance for NEC in terms of discrimination between NEC and sepsis (AUC, 0.997; 95% CI: 0.991–1.000 and 0.973; 95% CI: 0.932–1.000, respectively). Conclusions: Neonates with NEC manifested accelerated clot formation and higher clot strength compared to septic and healthy neonates, as these were expressed by ROTEM parameters. Impact: This work reports data on the hemostatic profile of neonates with necrotizing enterocolitis (NEC) using Rotational Thromboelastometry (ROTEM) and the capacity of ROTEM parameters in differentiating of NEC from sepsis at the disease onset. Neonates with NEC present acceleration of coagulation and exhibit a hypercoagulable profile, as this is expressed by ROTEM parameters, in comparison to septic and healthy neonates. ROTEM parameters demonstrated a good diagnostic capacity in differentiating NEC from sepsis at the disease onset. © The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc 2023

    "Simha Rotem (1924-2018): Ad memoriam. The broom and the resilience"

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    Simha Rotem was born in Warsaw in 1924. He was one of the most important member of the Warsaw Ghetto uprising in April 1943. Under the cover name of Kazik. He was a leader of the young Jews who were one of the first in Europe to rebel against the Nazi occupation. His original name is Symon Rathajzer, who upon his arrival in Israel he changed in Simha Rotem to symbolize a new beginning. His heroic and history is full of anecdotes that encroach of the unbelievable. Rotem came in and out of the ghetto, through the city’s sewers, besieged and burned, to bringing news and organizing the escape of the few survivors. Thanks to him the last fighters of the ghetto succeeded in acriding the “Aryan” area of the city, finding refuge from not Jewish people connected with the Polish resistance. In 1944 Rotem fighted in the Warsaw uprising against the Nazi occupation. He was one of the leader of the Jewish exodus from Poland to Israel. He contributed to save thousands of people. The author died in Jerusalem in 2018

    Measuring message gossiping in P2P networks and providing incentives in cryptocurrencies

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    Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2018.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 47-48).In this thesis, we present Plutus, an efficient and game-theoretically proven incentive mechanism for Algorand, a proof-of-stake cryptocurrency. In order to operate, Algorand requires users to constantly propagate messages but has no mechanism to incentivize users to do so. Plutus solves this problem by keeping track of each message propagation path and rewarding the users who propagated messages using a lottery. We implemented a prototype of Plutus on top of Algorand to measure the performance and overhead of Plutus. Experimental results show that with Plutus, Algorand's block confirmation time increases by only 7% and that there is no penalty on Algorand's scalability.by Rotem Hemo.M. Eng

    Non-self RNA sensing in virus infected cells and activation of antiviral immunity

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    Colloque organisé par Jean-Luc Imler (Université de Strasbourg) et Raul Andino (UCSF, USA) du 27 août au 1er septembre 2012 Participants Shizuo Akira, Raul Andino, Bruce Beutler, Stephen Cusack, Ding Shou-Wei, Takashi Fujita, Akira Tajima-Goto, Otto Haller, Jules Hoffmann, Veit Hornung, Jean-Luc Imler, Karim Majzoub, Carine Meignin, Eric Miska, Jan Rehwinkel, Carla Saleh, Rotem Sorek, Volker Thiel, Joao Trindade Marques, Ronald van Rij, Olivier Voinnet, Friedemann Weber -- Abstract Innate imm..

    Traceable Secret Sharing Based on the Chinese Remainder Theorem

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    Traceable threshold secret sharing schemes, introduced by Goyal, Song and Srinivasan (CRYPTO\u2721), allow to provably trace leaked shares to the parties that leaked them. The authors give the first definition and construction of traceable secret sharing schemes. However, the size of the shares in their construction are quadratic in the size of the secret. Boneh, Partap and Rotem (CRYPTO\u2724) recently proposed a new definition of traceable secret sharing and the first practical constructions. In their definition, one considers a reconstruction box RR that contains ff leaked shares and, on input tft-f additional shares, outputs the secret ss. A scheme is traceable if one can find out the leaked shares inside the box RR by only getting black-box access to RR and a private tracing key. Boneh, Partap and Rotem give constructions from Shamir\u27s secret sharing and Blakley\u27s secret sharing. The constructions are efficient as the size of the secret shares is only twice the size of the secret. In this work we present the first traceable secret sharing scheme based on the Chinese remainder theorem. This was stated as an open problem by Boneh, Partap and Rotem, as it gives rise to traceable secret sharing with weighted threshold access structures. The scheme is based on Mignotte\u27s secret sharing and increases the size of the shares of the standard Mignotte secret sharing scheme only by a factor of 22. We also introduce a new definition of semi-public secret sharing that does not require a private tracing key and give a construction based on the Chinese Remainder Theorem

    A Transitional Gundi (Rodentia: Ctenodactylidae) from the Miocene of Israel

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    abstract: We describe a new species of gundi (Rodentia: Ctenodactylidae: Ctenodactylinae), Sayimys negevensis, on the basis of cheek teeth from the Early Miocene of the Rotem Basin, southern Israel. The Rotem ctenodactylid differs from all known ctenodactylid species, including Sayimys intermedius, which was first described from the Middle Miocene of Saudi Arabia. Instead, it most resembles Sayimys baskini from the Early Miocene of Pakistan in characters of the m1-2 (e.g., the mesoflexid shorter than the metaflexid, the obliquely orientated hypolophid, and the presence of a strong posterolabial ledge) and the upper molars (e.g., the paraflexus that is longer than the metaflexus). However, morphological (e.g., presence of a well-developed paraflexus on unworn upper molars) and dimensional (regarding, in particular, the DP4 and M1 or M2) differences between the Rotem gundi and Sayimys baskini distinguish them and testify to the novelty and endemicity of the former. In its dental morphology, Sayimys negevensis sp. nov. shows a combination of both the ultimate apparition of key-characters and incipient features that would be maintained and strengthened in latter ctenodactylines. Thus, it is a pivotal species that bridges the gap between an array of primitive ctenodactylines and the most derived, Early Miocene and later, gundis.The article is published at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.015180
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