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    The importance of obtaining a more balanced relationship between the long and short food chain in the worldwide market for farm and food produce. A contribution to the debate on the capabilities of the short chain

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    Abstract- This paper is intended as an approach to the complex matter of the co-existence of long and short chains. It introduces a stimulus to further study these questions more thoroughly, which current market situations lead us to believe will be an interesting field, and one well worthy of consideration. The potentials and limits of short chain efficiency are analyzed in different contexts, in order to help identify its correct collocation in the search for the best combination of the different ways by which products can be released on the markets, with specific reference to the coexistence of the short and long chain. On this regard, a brief examination is also made of the effects of growing wholesaler power and the possibilities of a relevant control. Amongst other aspects, the paper highlights the fact that the relationship between short and long chain need not always be one of conflict, and refers particularly to the scope of agricultural-industrial districts. Context analysis, and specifically SWOT analysis, has been used to debate two different contexts. Many different situations have been examined and summarized, and amassed into two large context groups: developed and underdeveloped countries. The connections between short chain, self-centred development and protectionism are considered. The need is highlighted, and difficulty evaluated, of construction suitable models simulating alternative agricultural-food market function both on a local and global scale, also with reference to region and international trade growth models based on heterodox rather than orthodox development theories. This involves the need to identify emblematic indicators that are able to provide a summary expression of data and information to be included in these models in order to active them. As such, as set of indicators of the short chain juxtaposed to the long chain, suitable to assessing the social and economic, as well as environmental impacts, is proposed, and its validity discussed. The results of the analyses performed contribute towards evaluating and choosing the most appropriate options for the release of the product, for the different types of agricultural companies in different settings

    Polimorfismi genetici dell'interleuchina 1 e dell'interleuchina 6 nella popolazione sarda con particolare riferimento alle fasce di età avanzata

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    Introduction.A unique approach to the science of longevity is the natural model of centenarians. Studies of this kind are particularly interesting because they offer people the opportunity to know the critical factors that lead to aging successfully. It is indeed a population that is homogeneous for longevity, this term a long life regardless of its quality. The design and subsequent implementation of a genetic study is not without obstacles and barriers, both from an organizational perspective (research of centenarians and their validation by official records) and because we live in a multiethnic society. The data reported in the literature indicate that human longevity could be related to the optimal functioning of the immune system. So one of the genetic determinants of longevity might reside in those polymorphisms that regulate immune response. Centenarians are exceptional individuals, who through a mechanism not yet clarified, have developed a level of biological homeostasis that is compatible with the maintenance of life for an exceptional period of time. The project AKeA studied for over ten years, the phenomenon of longevity in Sardinia, a region in which there are constantly 22 centenarians per 100,000 inhabitants. The AKeA project is based on the methodology of certification: one study only individuals in possession of official documents and people in life who sign the informed consent and accept the researchers 'home visit' s University of Sassari. The work done in recent years has focused on the study of some cluster polymorphisms of interleukin 1 and interleukin 6. The study of interleukin 1 genes in the cluster, which expresses three different proteins, two agonists, interleukin-1 alpha and interleukin 1 beta and an antagonist, interleukin-1 Ra Materials and methods 1038 were examined DNA samples from Sardinian residents aged 60 years, and centenarians centenaries AKeA part of the project. The DNA was extracted, after drawing blood from white blood cells with the standard method of phenol-chloroform We studied three polymorphisms in the promoter of the gene for interleukin-6, -174 G / C, -597 G / A and -574 G / C. We studied two olymorphisms in the promoter of the gene for interleukin-1, -511 C / C and -889 C / T Furthermore, we studied interleukin-1 RA polymorphism that is linked to the presence of different alleles that differ in sequence repea t (VNTR) of 86 bp present in intron 2. 1038 samples were tested for DNA testing of which 849 were valid. The genotype distribution and allele frequency was estimated by dividing the individuals in the following age groups: centenarians, nova ntacinquenni, nonagenarians, octogenarians and sixties. In addition, a comparison was made between the sexes.Results.The distribution of genotypes of polymorphisms -174 G / C and -597 G / A for interleukin 6 follows the distribution expected under the Hardy-Weinberg equilibrium and there were no significant differences between the boomers and centenarians. The results for interleukin 1 did not show a meaningful if not for the distribution of genotypes among women nonagenarians, who do not follow the Hardy-Weinberg equilibrium. This figure is still the subject of extensive studies for his confirmation through the analysis of a larger sample

    From Surveillance to Solutions: Integrating Epidemiological Analysis with Web Application Development for Combatting Zoonotic Parasites in Gennargentu - Mandrolisai, Sardinia

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    This PhD thesis aims to provide an overview of the main zoonotic parasites. The objective is to offer an epidemiological insight into zoonotic parasitosis to develop a web application for raising awareness and preventing the risk of infection among citizens and farmers in Sardinia region. This endeavour aims to establish a foundation for the development and implementation of a telemedicine tool. The thesis is composed of following chapters: Chapter 1 contains a review article that comprehend a extensive summary of main zoonotic parasite that could be handled at parasitological laboratories and summarising the standard biosecurity protocols for the infectious agents. Chapter 2 is divided into two sections: Section 2.1 focuses on the epidemiological and molecular aspects of Apicomplexa parasites (Toxoplasma gondii, Neospora caninum,Sarcocystis spp.) in sheep intended for human consumption. In Section 2.2, the epidemiological aspects of T. gondii in Sardinian wild boar are described. Both surveys conducted reveal the widespread presence of T. gondii in both species. The prevalence varies depending on age and sex, and differences in prevalence are observed between the two species, leading to distinct epidemiological dynamics between wildlife and farmed animals. Chapter 3 examines the impact of Cystic Echinococcosis (CE) edutainment on children's awareness and understanding of the disease. An education project conducted among primary school children in Sardinia resulted in increased awareness of CE following the intervention. The findings suggest that edutainment can effectively enhance awareness and reduce the transmission of CE in endemic communities. Chapter 4 delineates the web application, highlighting its various sections: individual description pages for each parasite, interlinked with other pages detailing the project team's objectives, diagnostic services, and consulting offerings.This PhD thesis aims to provide an overview of the main zoonotic parasites. The objective is to offer an epidemiological insight into zoonotic parasitosis to develop a web application for raising awareness and preventing the risk of infection among citizens and farmers in Sardinia region. This endeavour aims to establish a foundation for the development and implementation of a telemedicine tool. The thesis is composed of following chapters: Chapter 1 contains a review article that comprehend a extensive summary of main zoonotic parasite that could be handled at parasitological laboratories and summarising the standard biosecurity protocols for the infectious agents. Chapter 2 is divided into two sections: Section 2.1 focuses on the epidemiological and molecular aspects of Apicomplexa parasites (Toxoplasma gondii, Neospora caninum,Sarcocystis spp.) in sheep intended for human consumption. In Section 2.2, the epidemiological aspects of T. gondii in Sardinian wild boar are described. Both surveys conducted reveal the widespread presence of T. gondii in both species. The prevalence varies depending on age and sex, and differences in prevalence are observed between the two species, leading to distinct epidemiological dynamics between wildlife and farmed animals. Chapter 3 examines the impact of Cystic Echinococcosis (CE) edutainment on children's awareness and understanding of the disease. An education project conducted among primary school children in Sardinia resulted in increased awareness of CE following the intervention. The findings suggest that edutainment can effectively enhance awareness and reduce the transmission of CE in endemic communities. Chapter 4 delineates the web application, highlighting its various sections: individual description pages for each parasite, interlinked with other pages detailing the project team's objectives, diagnostic services, and consulting offerings
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