292 research outputs found
Revamping Legacy- The Sustainable Transformation A Case Study of Anchal Leather Company Limited (ALCL)
The leather industry plays a crucial role in the global economy, contributing significantly to employment and exports. With major production hubs in key markets such as China, India, Italy, and Brazil, the industry continues to evolve to meet shifting consumer demands and environmental challenges. Anchal Leather Company Limited (ALCL) has established itself as a prominent player in this dynamic sector, known for its commitment to premium quality, innovative designs, and sustainable practices. By blending traditional craftsmanship with modern advancements, ALCL has expanded its product range to cater to diverse industries, including fashion, automotive, and luxury accessories. The company\u27s dedication to excellence, coupled with its focus on eco-friendly solutions, positions ALCL as a forward-thinking leader in the evolving leather market. As consumer preferences increasingly prioritize ethical and high-quality leather goods, ALCL remains committed to delivering innovative products that align with modern sustainability trends
Animal biotechnology : models in discovery and translation/ Edit.: Ashish S. Verma; Anchal Singh
xxix, 638 hal.: ill, tab.; 28 cm
Animal biotechnology : models in discovery and translation/ Edit.: Ashish S. Verma; Anchal Singh
xxix, 638 hal.: ill, tab.; 28 cm
Efficacy of Transcranial Direct Current Stimulation (tDCS) on working memory in College going students : A Randomized Clinical trial
we recruited forty healthy college going students for this research to improve the working memory by the application of tdcs and working memory task training in the experimental group and in control group only conventional working memory task given to perform . The Pre and post assessment was taken by two test digit span forward and digit span backward test and trail making test A and B . And result found more significant improvement in interventional group and improved working memory by the application of tdcs with working memory task training
Potential and Prospects of Dairy Busienss in Uttarakhand: A Case Study of Uttaranchal Cooperative Dairy Federation Limited
India is the leading milk producer in the world and the dairy cooperatives are the backbone of Indian dairy industry. This study has analyzed the inefficiencies existing in improving milk production, procurement pattern, marketing channels, and price spread of a dairy cooperative, Uttaranchal Cooperative Dairy Federation Ltd (UCDFL), also known as ‘Anchal’ in the Kumaun region of Uttarakhand and has proposed a model for eliminating these inefficiencies. It has been found that UCDFL is focused mainly on liquid milk marketing and has not adopted product diversification, which is the need of the day. Nainital and Almora districts of Kumaon region have been selected for the study; these cover almost 40 per cent of cattle population in the division, except Udham Singh Nagar. It has been found that due to insufficient margins, the number of agents working for other private dairies has increased. Different marketing channels for milk have been identified and price spread has been calculated for all the channels. Lack of business development services related to dairy industry has been found leading the farmers to disassociate from Anchal. The study has suggested that Anchal should evolve a definite policy with regard to procurement of milk in both lean and regular periods and to sustain its members, incentive package should be provided. Anchal should find ways to establish fodder banks at strategic locations for providing fodder during emergencies and periods of fodder scarcity. Local sale of milk at the society level should be encouraged to increase the popularity of Anchal brand.Agribusiness, Livestock Production/Industries,
In Situ Functionalized Fluorescent WS2-QDs as Sensitive and Selective Probe for Fe3+ and a Detailed Study of Its Fluorescence Quenching
Most of the reports suggest that liquid exfoliated WS2-QDs are unstable; therefore the need of present day is to develop a novel synthesis route for producing long-term stable WS2-QDs. Herein, we report a bottom-up single-step hydrothermal growth of in situ functionalized blue fluorescent WS2-QDs with stable fluorescence in aqueous media without subsequent treatments. Presence of various functional groups over the surface of f-WS2-QDs provides high solubility and stability to f-WS2-QDs in aqueous media preserving its fluorescence. Further, photoluminescence property of f-WS2-QDs has been employed to devise an optical sensor with a high sensitivity (K-D similar to 10(4) M-1) and selectivity for ferric (Fe3+) ions. Under the optimal condition, response of the sensor is found to be linear in the range of 0-55 mu M with a limit of detection (LOD) of 1.32 mu M, which is within the maximum permissible level of Fe3+ (similar to 5.4 mu M) in human drinking water by the USEPA. Further, we have also carried out a detailed evaluation on fluorescence quenching kinetics of f-WS2-QDs. Nonlinear behavior of S-V plot and TRPL measurements suggest that quenching is a mixed phenomenon of dynamic as well as static processes. Finally we have proposed a mechanism for fluorescence quenching of f-WS2-QDs in the presence of Fe3+.
Potential and Prospects of Dairy Busienss in Uttarakhand: A Case Study of Uttaranchal Cooperative Dairy Federation Limited
India is the leading milk producer in the world and the dairy cooperatives
are the backbone of Indian dairy industry. This study has analyzed the
inefficiencies existing in improving milk production, procurement pattern,
marketing channels, and price spread of a dairy cooperative, Uttaranchal
Cooperative Dairy Federation Ltd (UCDFL), also known as ‘Anchal’ in the
Kumaun region of Uttarakhand and has proposed a model for eliminating
these inefficiencies. It has been found that UCDFL is focused mainly on
liquid milk marketing and has not adopted product diversification, which
is the need of the day. Nainital and Almora districts of Kumaon region
have been selected for the study; these cover almost 40 per cent of cattle
population in the division, except Udham Singh Nagar. It has been found
that due to insufficient margins, the number of agents working for other
private dairies has increased. Different marketing channels for milk have
been identified and price spread has been calculated for all the channels.
Lack of business development services related to dairy industry has been
found leading the farmers to disassociate from Anchal. The study has
suggested that Anchal should evolve a definite policy with regard to
procurement of milk in both lean and regular periods and to sustain its
members, incentive package should be provided. Anchal should find ways
to establish fodder banks at strategic locations for providing fodder during
emergencies and periods of fodder scarcity. Local sale of milk at the society
level should be encouraged to increase the popularity of Anchal brand
Animal biotechnology : models in discovery and translation / edited by Ashish S. Verma, Amity Institute of Biotechnology, Amity University Uttar Pradesh, NOIDA (UP), India, Anchal Singh, Amity Institute of Biotechnology, Amity University Uttar Pradesh, NOIDA (UP), India.
pharmacy bookfair2016Includes bibliographical references and index.xxix, 620 pages :Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field. Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseasesProvides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering
Occupational Stress at Workplace: A Case Study of Private Colleges in Varanasi
The main focus of the study is to ascertain the stress amongst the faculties of higher education in private colleges at Varanasi. It has been found that high level of occupational stress can cause irritation, anxiety, ineffectiveness, depression and lower job satisfaction. The key objective of this study was to assess the level of occupational stress, causes and consequences among the faculties. Among the twelve occupational stressors gauged in the study, using Occupational Stress Index by A.K. Srivastava and A.P. Singh, role overload and role conflict was found to be with maximum variance among the faculties. It has also been observed that unfair distribution of work and under participation influences satisfaction and well-being of faculty members at workplace in Varanasi. Implications of this research from the perspective of better stress management among faculty members are discussed.</jats:p
Development of Fluorescence Microscopy Approaches to Study Subcellular Protein Transport and Enzymatic Activity
Understanding the subcellular localization of proteins and their activity is important in understanding their normal function in eukaryotic cells. Fluorescence cellular imaging techniques can selectively and sensitively visualize subcellular biochemistry. Using this approach, two different methods were employed in this thesis. The first focused on studying protein import into peroxisome and the other on monitoring the activity of an endoplasmic reticulum (ER)-localized enzyme, human carboxylesterase 1 (CES1).
Peroxisomes are mainly known as the center for long chain fatty acid b-oxidation as well as the production and detoxification of hydrogen peroxide. Proteins which are needed in the peroxisomes are encoded in the nucleus and synthesized in the cytosol which are then transported to the peroxisomes with the help of a sophisticated protein-transport machinery. Pex5 is one of the key transport proteins responsible for carrying proteins tagged with the peroxisome targeting sequence 1 (PTS-1). The peptide signals that target proteins to the peroxisomes, however, are poorly studied in human cell lines. While different PTS-1 targeting sequences are known to have different efficiencies in being delivered to the peroxisomes, no study has cataloged all known localization signals under the same conditions in human cells. Thus, the aim of the first part of thesis is to design a method to quantify the peroxisome targeting ability of a peptide sequence.
In second part of this thesis, ER-localized CES1 is an enzyme that plays a key role in ester-containing drug metabolism. CES1 is known to have a high degree of genetic variation through a variety of mechanisms including single nucleotide polymorphisms (SNPs) producing CES1 forms that have reduced metabolism of ester-containing drugs, such as methylphenidate (Ritalin; treats ADD), oseltamivir (Tamiflu; treats the flu), and trandolapril (Mavik; treats high blood pressure). Thus, depending on a patient’s genetics they may produce a form of CES1 that metabolizes a drug at different rate than somebody who has another genetic form of CES1. This has led to different clinical outcomes for patients. Current methods for studying CES1 typically require relatively large sample sizes and purification steps to isolate CES1 metabolites before analysis. To address this, fluorescent probes have been developed but to date there are only two well-characterized probes that can report on CES1 activity in live cells. Overall, having a variety of fluorescent CES1 probes with different properties would allow researchers to choose the one that is best suited for use in the system of their interest. To address this, Fluorescein-based CES1 Probe 1 (FCP-1) was developed and evaluated for its ability to monitor CES1 activity in living cells using epifluorescence microscopy. Studies with small molecule inhibitors and genetic manipulations indicate that FCP-1 can specifically report on CES1 activity in human cell lines. As a whole, this thesis demonstrates that fluorescence microscopy can be a powerful tool in studying subcellular biochemical processes in live cells
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