721 research outputs found
Hydrogeochemical investigation and groundwater quality assessment of Pratapgarh district, Uttar Pradesh
No full textAssessment of Mine Water Quality Using Heavy Metal Pollution Index in a Coal Mining Area of Damodar River Basin, India
No full textAssessment of Hydrogeochemical Processes and Mine Water Suitability for Domestic, Irrigation, and Industrial Purposes in East Bokaro Coalfield, India
No full textGIS based evaluation of fluoride contamination and assessment of fluoride exposure dose in groundwater of a district in Uttar Pradesh, India
No full textHydrogeochemical characterization and groundwater quality assessment in a coal mining area, India
No full textThe present study determines major and trace element chemistry of groundwater in the West Bokaro coalfield to assess the hydrogeochemical processes and groundwater quality for drinking and irrigation uses. For this urpose, 33 groundwater samples from different mining areas of the West Bokaro coalfield were collected and analysed for pH, electrical conductivity (EC), total dissolved solid (TDS), dissolved silica (SiO2), major cations (Ca2+, Mg2+, Na+, K+), anions (F−, Cl−, HCO3−, SO42− and NO3−) and trace metals (Mn, Cu, Pb,Zn, Ni, Co, As, Se, Al, Cd, Cr, Ba and Fe). The analytical results show the slightly acidic to alkaline nature of groundwater and dominance of HCO3− and SO42− in anionic and Ca2+ and Na+ in cationic abundance. High SO42− concentrations are attributed to the oxidative weathering of pyrite and gypsum dissolution. Supersaturation condition with respect to dolomite and calcite for most samples may result from the dissolution of gypsum after the water is saturated with respect to the carbonate minerals. The data plot on the Gibbs and Piper diagrams revealed that the groundwater chemistry is mainly controlled by rock weathering with secondary contribution from anthropogenic sources. In a majority of the groundwater samples, alkaline earth metals exceed alkalies and strong acids dominate over weak acid. Ca-Mg-HCO3, Ca-Mg-SO4-Cl and Ca-Mg-SO4 were the dominant hydrogeochemical facies. A comparison of groundwater quality parameters in relation to specified limits for drinking water shows that the concentrations of TDS, SO42−, NO3−, total hardness (TH), Fe and Ni are exceeding the desirable limits in many groundwater samples. Quality assessment for irrigation uses reveal that the groundwater is of good to suitable category. Higher salinity and magnesium hazard values at some sites restrict the suitability of groundwater for irrigation purposes
Estimation of Heavy Metal Contamination in Groundwater and Development of a Heavy Metal Pollution Index by Using GIS Technique
No full textHeavy metal (Al, As, Ba, Cr, Cu, Fe, Mn, Ni, Se and Zn) concentration in sixty-six groundwater samples of the West Bokaro coalfield were analyzed using inductively coupled plasma-mass spectroscopy for determination of seasonal fluctuation, source apportionment and heavy metal pollution index (HPI). Metal concentrations were found higher in the pre-monsoon season as compared to the post-monsoon season. Geographic information system (GIS) tool was attributed to study the metals risk in groundwater of the West Bokaro coalfield. The results show that 94 % of water samples were found as low class and 6 % of water samples were in medium class in the post-monsoon season. However, 79 % of water samples were found in low class, 18 % in medium class and 3 % in high class in the pre-monsoon season. The HPI values were below the critical pollution index value of 100. The concentrations of Al, Fe, Mn, and Ni are exceeding the desirable limits in many groundwater samples in both season
Evaluation of metal contamination and risk assessment to human health in a coal mine region of India: A case study of the North Karanpura coalfield
No full textEvaluation of hydrogeochemical processes and groundwater quality in the Jhansi district of Bundelkhand region, India
No full textBeneficial Effects of Dietary Polyphenols on Gut Microbiota and Strategies to Improve Delivery Efficiency
No full textThe human intestine contains an intricate ecological community of dwelling bacteria, referred to as gut microbiota (GM), which plays a pivotal role in host homeostasis. Multiple factors could interfere with this delicate balance, including genetics, age, antibiotics, as well as environmental factors, particularly diet, thus causing a disruption of microbiota equilibrium (dysbiosis). Growing evidence support the involvement of GM dysbiosis in gastrointestinal (GI) and extra-intestinal cardiometabolic diseases, namely obesity, and diabetes. This review firstly overviews the role of GM in health and disease, then critically reviews the evidence regarding the influence of dietary polyphenols in GM based on preclinical and clinical data, ending with strategies under development to improve the efficiency of delivery. Although the precise mechanisms deserve further clarification, preclinical and clinical data suggest that dietary polyphenols present prebiotic properties and exert antimicrobial activities against pathogenic GM, having benefits in distinct disorders. Specifically, dietary polyphenols have been shown the ability to modulate GM composition and function, interfering with bacterial quorum sensing, membrane permeability, as well as sensitizing bacteria to xenobiotics. In addition, can impact gut metabolism and immunity and exert anti-inflammatory properties. In order to overcome the low bioavailability, several different approaches have been developed, aiming to improve the solubility and transport of dietary polyphenols throughout the GI tract and deliver in the targeted intestinal regions. Although more research is still needed, particularly translational and clinical studies, the biotechnological progress achieved during the last years opens up good perspectives to, in a near future, be able to improve the use of dietary polyphenols modulating GM in a broad range of disorders characterized by a dysbiotic phenotype
Investigation of Serum Pro-Inflammatory Markers and Trace Elements Among Short Stature in Eastern Uttar Pradesh and Bihar Populations
No full textAbhay Kumar Yadav,1 Nitish Kumar Singh,1 Ankur Singh,2 Ashish Ashish,3 Suchitra Singh,1 Sachchida Nand Rai,4 Santosh Kumar Singh,4 Royana Singh1 1Department of Anatomy, Institute of Medical Science, Banaras Hindu University, Varanasi, UP, 221005, India; 2Department of Pediatrics, Institute of Medical Science, Banaras Hindu University, Varanasi, UP, 221005, India; 3Multidisciplinary Research Unit, Institute of Medical Science, Banaras Hindu University, Varanasi, UP, 221005, India; 4Centre of Experimental Medicine and Surgery, Institute of Medical Science, Banaras Hindu University, Varanasi, UP, 221005, IndiaCorrespondence: Royana Singh, Department of Anatomy, Institute of Medical Science, Banaras Hindu University, Varanasi, UP, 221005, India, Email [email protected]: Short stature is prevalent among children worldwide, particularly in developing countries. Various trace elements, including zinc, magnesium, iron, copper, chromium and selenium, are crucial for proper body development. The aim of this study is to explore the relationship between trace elements and TNF-α and IL-6 to elicit and possible pathway responsible for short stature.Methods: Two hundred and twenty samples were recruited for this study, 100 short statures and 120 controls were randomly selected. Six trace elements were measured using graphite furnace atomic absorption spectrometry. The concentrations of IL-6 and TNF-α in serum were assessed utilizing the Enzyme-Linked-Immunosorbent Assay (ELISA). Superoxide dismutase was also analysed to determine the oxidative stress response.Results: The study revealed notable distinctions in serum trace element levels of short stature. They exhibited significant lower levels of zinc and magnesium, alongside higher levels of copper. The altered Cu/Zn ratio seemed to have a positive correlation with short stature. Conversely, no significant disparities were observed in iron, chromium, and selenium levels. Furthermore, a significant rise was noted in proinflammatory marker TNF-α and cytokine IL-6. Additionally, superoxide dismutase was low in the short statures In silico study shows a high affinity of Zinc with TNF alpha. It may be suggested that inflammation at any time during childhood, with the rise in TNF alpha tightly binds with zinc and may have led to a decrease in zinc serum levels, altered redox homeostasis and resulted in short stature.Conclusion: The altered Cu/Zn ratio along with high TNF alpha and IL6 may be used as a marker for short stature in the initial years of growth in children before they reach maturity at the age of 18. Thereafter, introducing zinc supplementation could potentially enhance stature by mitigating TNF-alpha level. Further experimental studies will help to establish the exact role of zinc with TNF alpha in short stature.Keywords: short stature, zinc, trace element, superoxide dismutase and inflammatio
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