14 research outputs found
Association Between Industry Sponsorship and Author Conflicts of Interest With Outcomes of Systematic Reviews and Meta-Analyses of Interventions for Opioid Use Disorder
Introduction: Author conflicts of interest (COI) and industry sponsorship may lead to biased research results and conclusions. Considering the direct influence that systematic reviews have on patient care, including the management of patients being treated for opioid use disorders (OUD), these studies should be free of industry bias. Thus, we sought to determine whether a relationship exists between COI and the favorability of systematic review outcomes using a sample of systematic reviews regarding OUD interventions.
Methods: We searched MEDLINE and Embase for systematic reviews and meta-analysis related to OUD treatment. The study team performed all data extraction in a masked duplicate fashion. We searched for undisclosed COI for each systematic review author in 3 databases--the CMS Open Payments database, Dollars for Profs, and the United States Patent and Trademark Office (USPTO). The research team quantified results using descriptive statistics. We evaluated associations between review characteristics using Fisher\u27s exact tests, when possible.
Results: This article includes seventeen systematic reviews and meta-analyses with 81 authors. We found that 25 authors (30.9%) had some form of COI, and 22 (of 25, 88.0%) authors had an undisclosed COI. However, no significant association existed between COI and favorability of results and conclusions. Notably, two systematic reviews (of 17; 11.76%) were industry-sponsored. Similarly, we found no association between the study sponsor source and the favorability of systematic review results and conclusions.
Conclusions: Our results suggest the favorability of systematic review results and conclusions are not influenced by author COI or industry sponsorship. However, nearly one-fourth of authors had an undisclosed COI, further emphasizing the need for standardization and adherence to COI disclosure policies within addiction medicine literature
Evidence of financial conflicts of interest in authors of opioid use disorder related systematic reviews and meta-analyses.
Evidence of financial conflicts of interest in authors of opioid use disorder related systematic reviews and meta-analyses.
Evaluation of quality of abstracts in systematic reviews related to pediatric strabismus therapies
Evaluation of quality of abstracts in systematic reviews related to pediatric strabismus therapies
Evaluation of quality of abstracts in systematic reviews related to pediatric strabismus therapies
Evidence of financial conflicts of interest in authors of opioid use disorder related systematic reviews and meta-analyses.
Literary ego-document by Jiří Orten
Práce se bude zabývat zejména deníky a korespondencí Jiřího Ortena, bude je analyzovat a následně objasňovat jejich význam v rámci celé autorovy tvorby. Deníky Jiřího Ortena jsou velice specifickou položkou v jeho díle, mají velký význam v rámci autorova uměleckého uvažování o svém psaní, ale i o literárních pracích soudobých autorů, které četl. Následně budou jeho deníky komparovány s dalšími dobovými ego-dokumenty, zejména se Šlépěji Jakuba Demla. To vše se bude odehrávat na pozadí Ortenovy životní situace a zkušenosti.This work will especially occupy with diary and correspondence of Jiří Orten, it will analyse them and afterwards clarify their meaning under the whole author creation. The diaries of Jiří Orten are very specific item in his writings, have a big meaning under the author art thinking about his writing but as well as about literary works of contemporary authors. Afterwards his diaries will be comparised with another period ego-documents. In this respect there are very distinctive Deml´s Šlépěje. That all will take place in background of Orten´s life situation and experience.Ústav historických vědPředstavení práce autorkou. Seznámení komise s posudky. Rozprava nad posudky a následná diskuse. (co je literární ego - dokument a příklady v české literatuře, Ortenovy vzory).Dokončená práce s úspěšnou obhajobo
