10,622 research outputs found
Art, Biography, Sexuality: Patrick Procktor and Keith Vaughan
No full textThis critical review forms a reflection on the research published within the following publications:
Patrick Procktor: Art and Life (Unicorn Press, 2010)
Keith Vaughan: The Mature Oils 1946-1977, (Sansom & Co., 2012)
The research is on two artists, Patrick Procktor (1936-2003), and Keith Vaughan (1912-1977). The monograph on Procktor – previously one of the least documented of the generation of artists who came to prominence in London in the Sixties – positions him in a history of art from which he had been notably absent. The research on Vaughan asserts a new reading of his work, one that is both deeper and more nuanced in its analysis of the ways in which personal experience and sexuality are encoded autobiographically within his work. Crucially, in both artists biography and work are symbiotically linked; the research therefore examines the links between life and art.
Revisionary in intent, the work examines trajectories of experience of gay British (or rather, English) artists in the twentieth century, artists who sought to express themselves and forge careers within the constraints of a heteronormative society, albeit one in which attitudes to sexuality were undergoing change. As gay men, both were constrained by the social mores of their times, and each used painting as a means to affirm personal and sexual identities. A key research interest is in the ways in which sexuality and persona are reflected in critical responses to the artist’s work: in Vaughan, Procktor and other gay male artists of the period. The writing on both Procktor and Vaughan examines the relationship between their personal and professional/artistic lives, framed within a broader socio-political and art historical context. It asserts the place of biography as a means to understand and form new readings of the work. The work adds substantially to the literature and wider discourse on post-war British painting and social history
Patrick Chamoiseau Recovering Memory
No full textThis timely new book skillfully examines the work of the award-winning writer Patrick Chamoiseau. Considered by many as one of the most innovative writers to hit the French literary scene in over 40 years, Chamoiseau made his name with his book Texaco (published in 1992 and winner of the highest literary prize in France, the Prix Goncourt). His books have gone on to sell millions and his work has been translated by a number of academic presses. McCusker sets the author in context, providing a valuable contribution to 'memory studies' by looking at literary representation of memory in Martinique, a society founded on slavery but now politically assimilated to the metropolitan centre, France.Title Page -- Contents -- Introduction -- 1: Beginnings: The Enigma of Origin -- 2: 'Une tracée de survie': Autobiographical Memory -- 3: Memory Re-collected: Witnesses and Words -- 4: Memory Materialized: Traces of the Past -- 5: Flesh Made Word: Traumatic Memory in Biblique des derniers gestes -- Afterword -- Notes -- Bibliography -- IndexThis timely new book skillfully examines the work of the award-winning writer Patrick Chamoiseau. Considered by many as one of the most innovative writers to hit the French literary scene in over 40 years, Chamoiseau made his name with his book Texaco (published in 1992 and winner of the highest literary prize in France, the Prix Goncourt). His books have gone on to sell millions and his work has been translated by a number of academic presses. McCusker sets the author in context, providing a valuable contribution to 'memory studies' by looking at literary representation of memory in Martinique, a society founded on slavery but now politically assimilated to the metropolitan centre, France.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
The contribution of the Fc RIIB immunoreceptor tyrosine-based inhibitory motif (ITIM) to the modulation of antibody immunotherapy
No full textMonoclonal antibodies (mAb) are an increasingly important therapeutic tool in the treatment of cancers and autoimmunity. Many mAbs elicit their efficacy through engagement of activatory Fc gamma receptors (Fc R), resulting in target cell depletion by immune effector cells. These activatory Fc Rs are negatively influenced by the single inhibitory Fc R, Fc RIIB. Fc RIIB has been shown to reduce the efficacy of mAbs through impairment of activatory Fc R function and upregulation of Fc RIIB has been identified as a resistance mechanism of mAb therapeutics in cancer. Fc RIIB contains an intracellular immunoreceptor-tyrosine-based inhibition motif (ITIM), which delivers inhibitory signalling. Whether the ITIM is required for all Fc RIIB-mediated inhibitory activities of therapeutic mAbs is not yet clear. To address this issue, we developed and characterised a novel transgenic mouse model (NoTIM), in which the endogenous inhibitory mouse (m)Fc RII is replaced with a non-signalling ITIM mutant of human (h)Fc RIIB. Cells from mice expressing the NoTIM receptor were no longer able to elicit phosphorylation of the Fc RIIB ITIM, mediate efficient internalisation of immune complexes or prevent anti-IgM-mediated calcium flux, confirming the expected phenotype. To understand how Fc RIIB inhibitory signalling impacted mAb-mediated depletion of target cells, NoTIM mice were treated with anti-mouse CD20 mAbs. The extent of depletion was compared to mice either lacking mFc RII or where mFc RII was replaced with a signalling competent hFc RIIB (hFc RIIB Tg). B cell depletion was reduced in both the NoTIM and hFc RIIB Tg mice compared to those lacking mFc RII. Subsequent experiments revealed this was not due to accelerated mAb internalisation nor enhanced clearance from the serum. Using a series of adoptive transfer models we determined that the NoTIM hFc RIIB was mediating inhibition, by competing with activatory Fc Rs on the surface of myeloid cells for the Fc of the direct targeting mAb. These findings were then assessed with respect to T regulatory cell and malignant murine B cell depletion. It was found that in both cases, depletion was negatively impacted by the expression of Fc RIIB at themyeloid surface rather than by its ability to signal. These data indicate that signalling through the ITIM is not critical for the ability of hFc RIIB to prevent mAb-mediated depletion of target cells, questioning current paradigms for its mechanism of action
Book Review: <i>The Modern Stephen King Canon</i>:<i>Beyond Horror </i>by Philip L. Simpson and Patrick McAleer
No full textThe Modern Stephen King Canon: Beyond Horror by Philip L. Simpson and Patrick McAleer published by Lexington Books (2019)Book review by Lauren ChristieWinter: Issue 2: Halloween (2019): The Journal of Stephen King Studie
Book Review: <i>The Modern Stephen King Canon</i>:<i>Beyond Horror </i>by Philip L. Simpson and Patrick McAleer
No full textThe Modern Stephen King Canon: Beyond Horror by Philip L. Simpson and Patrick McAleer published by Lexington Books (2019)Book review by Lauren ChristieWinter: Issue 2: Halloween (2019): The Journal of Stephen King Studie
Replication Data for: Endogenous Price Commitment, Sticky and Leadership Pricing: Evidence from the Italian Petrol Market
No full textThe do-file contains the code to replicate "Endogenous Price Commitment, Sticky and Leadership Pricing: Evidence from the Italian Petrol Market", published in the International Journal of Industrial Organization, vol. 40(C), pages 32-48, by Patrick Andreoli-Versbach and Jens-Uwe Franck.
Contact author is Patrick Andreoli-Versbach. E-Mail: [email protected]
Replication Data for: Endogenous Price Commitment, Sticky and Leadership Pricing: Evidence from the Italian Petrol Market
No full textThe do-file contains the code to replicate "Endogenous Price Commitment, Sticky and Leadership Pricing: Evidence from the Italian Petrol Market", published in the International Journal of Industrial Organization, vol. 40(C), pages 32-48, by Patrick Andreoli-Versbach and Jens-Uwe Franck.
Contact author is Patrick Andreoli-Versbach. E-Mail: [email protected]
The investigation in "Dora Bruder" of Patrick Modiano
No full textreservedIl presente lavoro si propone di affrontare il tema dell’indagine, dell’inchiesta investigativa nel romanzo “Dora Bruder” dello scrittore francese Patrick Modiano, pubblicato nel 1997. Si tratta del più noto successo editoriale dell’autore, il quale, in una narrazione al contempo biografica ed autobiografica, si mette sulle tracce di Dora Bruder, una giovane ragazza ebrea scomparsa nel 1941, di cui si sono perse definitivamente le tracce. La presente tesi si compone di tre capitoli. Nel primo, si analizzeranno i motivi che spingono l’autore ad occuparsi della vicenda della giovane ragazza scomparsa proprio durante la seconda guerra mondiale. Successivamente, nel secondo capitolo, si passerà ad affrontare come l’autore compie la propria indagine per comprendere che cosa le sia accaduto, diventando una sorta di investigatore su un vecchio caso di scomparsa. Ed infine, nell’ultimo capitolo, si analizzerà quale sarà l’esito della sua indagine.This work proposes to deal with the subject of investigation in the novel "Dora Bruder" by French writer Patrick Modiano, published in 1997. It’s the most known publishing success of the author, which, in a narrative in the meantime biographical and autobiographical, goes on the trail of Dora Bruder, a young Jewish girl disappeared in 1941, of whom all traces have been definitively lost. This thesis is composed by three chapters. In the first, we will analyse the reasons why the author deal with the story of the young girl vanished during the Second World War. Then, in the second chapter, we will approach how the author does his own investigation to understand what happened to her, becoming sort of a detective on an old case of disappearence. Finally, in the last chapter, we focus on which it’ll be the outcome of his investigation
LIKE WILD / Ray Anthony and his Orchestra
No full textComprend : ROOM 43 / Ken Jones - FALL OUT / Henry Mancini - KUKIE BIRD / Anthony ; Simpson ; Patrick - DARK EYES / arr. par Anthony ; Simpson ; Patrick - PETER GUNN / Henry Mancini - WRONG NUMBER / Anthony ; Simpson ; Patrick - 707 / Anthony ; Simpson ; Scott - SWANEE RIVER / arr. par Ray Anthony ; Kirk Patrick - FLY NOW, PAY LATER / Anthony ; Simpson ; Scott - BUNNY HOP ROCK / Ray Anthony ; Leonard Auletti - ROCK-UMBA / Joe Weiss - WALKIN' TO MOTHER'S / Henry ManciniBnF-Partenariats, Collection sonore - BelieveContient une table des matière
On Translating Burns: A Heavenly Paradise and Two Versions of "A Red Red Rose"
No full textThis essay explores the stylistic textures and content of a key song by Robert Burns and investigates the possible translation strategies to be used for this kind of text. The in-between nature of Burns's songs - half-way between proper poetic texts written for the page and songs to be sung - represent a real challenge for the translator in any language. The author here uses some of the key translation theories and formulates his own solutions
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