1,721,048 research outputs found
On-ward observations in neonatal intensive care: Towards safer supplemental oxygen & IV therapy
The focus of this thesis is on supplemental oxygen therapy and intrave nous (IV) therapy in neonatal intensive care. Both therapies are essential, but potentially dangerous for (preterm) newborn infants.\u81 Supplemental oxygen therapy refers to the therapy where a gas mixture with >21% of oxy gen is supplied to the patient via (mechanical) ventilation to reach and maintain adequate tissue oxygenation. Unfortunately the accurate manual control of the oxygenation in newborn infants is difficult and time consuming. \u81 In IV therapy various types of nutrition, drugs, and/or fluids are administered directly into the veins of the patient. Although it is expected that the IV substances are supplied to the patient with the pre-programmed flow-rate, the actual volume delivery varies over time. Particularly in newborn infants, these sudden changes in delivered volume can have severe consequences. The objective of the research was to determine the limitations of supplemental oxygen therapy and IV therapy in current neonatal intensive care and to identify areas for improvements. To meet the objective, several studies were performed including on-ward observations. The overall conclusion is that in both therapies (unregistered) variations in clinical practice are present. It is to be expected that these unnoticed differences in care lead to differences in outcome of patients. To achieve a more standardised approach and to improve the safety of both supplemental oxygen therapy and IV therapy, in this thesis several recommendations are provided.BioMechanical EngineeringMechanical, Maritime and Materials Engineerin
The Improvement of Strabismus Surgery: The Role of the Suspension of the Human Eye
BioMechanical EngineeringMechanical, Maritime and Materials Engineerin
Quantification of deformation and sliding of orbital fat during rotation of the eye
The anatomy of the eye is well known, however the mechanical properties and behaviour of the eye are not well known. Knowing these properties could potentially be an improvement for preoperative planning in orbital surgery. To get a better understanding of the mechanical properties of the eye while it is in movement a Finite Element Model (FEM) has been developed at the TU Delft by Schutte et al. [1]. For the FEM it is important to quantify what part of movement is sliding and what part is deformation because both are modelled in a different manner. We present a complete pipeline to quantify sliding from MRI image volumes. The registration methods previously applied to the orbit are unable to deal with sliding. Therefore, two methods developed for registration problems where sliding occurs are tested for applicability to the orbit using phantoms. The method developed by Berendsen et al. [2], or sliding splines method, performs best on the phantoms, and is applied to the orbit. The results of the sliding splines method are compared to results from regular B-splines registration which has been the registration method used in the orbit up until this project. Amelon et al. [3] have developed a method to characterize sliding from displacement fields, which has never been applied to the orbit. We applied this method to the displacement field generated by the regular B-splines registration and the sliding splines method. Comparison of both registration methods, using the characterization method, shows that methods previously applied to the orbit are unable to preserve sliding in their displacement field. The sliding splines method is able to preserve sliding, but also introduces sliding in regions where it does not occur. We conclude that further study into registration methods that allow for sliding is necessary. Especially, into the sliding splines method since it is able to preserve sliding and shows promising results.Computer graphics and visualizationElectrical Engineering, Mathematics and Computer Scienc
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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